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Levofloxacin (cas 100986-85-4) Molecular Structure

Levofloxacin(CAS No. 100986-85-4)

  • Molecular Formula: C18H20FN3O4
  • Molecular Weight:

Identification of 100986-85-4

  • Name:Levofloxacin
  • Molecular Formula:C18H20FN3O4
  • CAS Registry Number:100986-85-4
  • Synonyms: Elequine;(-)-Ofloxacin;7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6- carboxylic acid,9-fluoro-2,3-dihydro-3- methyl-10-(4-methyl-1-piperazinyl)-7-oxo-,(3S)-;Levaquin (TN);Levofloxacino [INN-Spanish];Levofloxacin (JAN/USAN);Levaquin;Levofloxacin [USAN:INN:JAN];Levofloxacine [INN-French];(S)-Ofloxacin;Ofloxacin S-(-)-form;Iquix;(S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid;Levofloxacinum [INN-Latin];7H-Pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid, 2,3-dihydro-9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-, (S)-;(S)-(-)-Ofloxacin;8-fluoro-3-methyl-9-(4-methyl-piperazin-1-yl)-6-oxo-2,3-dihydro-6H-1-oxa-3a-aza-phenalene-5-carboxylic acid;Levoflaoxacin;Levofloxacincas;
  • Molecular Structure:Levofloxacin C18H20FN3O4 (cas 100986-85-4) Molecular Structure

Chemical Properties

  • Density:1.48 g/cm3
  • Water solubility:Insoluble
  • Boiling Point:571.5 oC at 760 mmHg
  • Melting Point:218 oC
  • Flash Point:299.4 oC
  • Storage Temperature:Store at 0-5°C
  • Solubility:Insoluble
  • Appearance:off-white to yellow crystals
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Purity:99.5% , levofloxacin English name: Ofloxacin Chemical name: (±)-9-fluorine-2, 3-2 hydrogen-3-methyl-10-(4-methyl-1-ofloxacin base)-7-oxygen generation-7 H-pyridine and [1, 2, 3-DE]-[1, 4] benzene and the evil polybenzoxa..
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CAS: 100986-85-4 MF: C 18 H 20 FN 3 O 4 MW: 361.37 Melting point : 218ºC Characters : Y ellow or light yellow clear crystal powder Specific rotation : -95°~-103° Identification : Should be Positive reactio..
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EC NO: INCHI: MF:C 18 H 20 FN 3 O 4 MW:361.37 Synonyms: Ofloxacin;(+-)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid;7H-Pyrido(1,2,3-de)-1,4-benzox..
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EC NO: MF:C18H20FN3O4 Synonyms:Ofloxacin;(+-)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid;7H-Pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid, ..
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References of Levofloxacin

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
monkey LD50 oral > 250mg/kg (250mg/kg) SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Arzneimittel-Forschung. Drug Research. Vol. 42, Pg. 365, 1992.
mouse LD50 oral 1803mg/kg (1803mg/kg) SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Arzneimittel-Forschung. Drug Research. Vol. 42, Pg. 365, 1992.
rat LD50 oral 1478mg/kg (1478mg/kg) SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Arzneimittel-Forschung. Drug Research. Vol. 42, Pg. 365, 1992.
women TDLo oral 122mg/kg/10D- (122mg/kg) MUSCULOSKELETAL: OTHER CHANGES Annals of Pharmacotherpy. Vol. 33, Pg. 792, 1999.
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Safety

Hazard Codes:?HarmfulXn
Risk Statements: 22-42/43-68-20/21/22
R22:Harmful if swallowed.?
R42/43:May cause sensitization by inhalation and skin contact.?
R68:Possible risk of irreversible effects.?
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.
Safety Statements: 26-36/37/39-36?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.?
S36:Wear suitable protective clothing.
WGK Germany: 3
RTECS of Levofloxacin (CAS NO.100986-85-4): UU8815550