
Organism
Test Type
Route
Reported Dose (Normalized Dose)
Effect
Source
monkey
LD50
oral
> 250mg/kg (250mg/kg)
SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSIONArzneimittel-Forschung. Drug Research. Vol. 42, Pg. 365, 1992.
mouse
LD50
oral
1803mg/kg (1803mg/kg)
SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSIONArzneimittel-Forschung. Drug Research. Vol. 42, Pg. 365, 1992.
rat
LD50
oral
1478mg/kg (1478mg/kg)
SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSIONArzneimittel-Forschung. Drug Research. Vol. 42, Pg. 365, 1992.
women
TDLo
oral
122mg/kg/10D- (122mg/kg)
MUSCULOSKELETAL: OTHER CHANGES
Annals of Pharmacotherpy. Vol. 33, Pg. 792, 1999.
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Hazard Codes:?
Xn
Risk Statements: 22-42/43-68-20/21/22
R22:Harmful if swallowed.?
R42/43:May cause sensitization by inhalation and skin contact.?
R68:Possible risk of irreversible effects.?
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.
Safety Statements: 26-36/37/39-36?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.?
S36:Wear suitable protective clothing.
WGK Germany: 3
RTECS of Levofloxacin (CAS NO.100986-85-4): UU8815550