Fasudil hydrochloride (cas 105628-07-7) Molecular Structure

CAS No. 105628-07-7 (Fasudil hydrochloride )

Molecular Formula: C14H18ClN3O2SMolecular Weight: 327.82962

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  • Hydrochloride Fasudil

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    DetailDesc:CAS: 105628-07-7 M.F.:C14H17N3O2S稨Cl M.W.:327.83

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  • Fasudil Hydrochloride

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    DetailDesc: Name:Fasudil Hydrochloride Cas No.:105628-07-7 Molecular Formula: C 14 H 17 N 3 O 2 S.HCl Formula Weight: 327.83

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    DetailDesc:Name: Fasudil hydrochloride Synonyms: Isoquinoline,5-[(hexahydro-1H-1,4-diazepin-1-yl)sulfonyl]-, hydrochloride (1:1);1H-1,4-Diazepine,hexahydro-1-(5-isoquinolinylsulfonyl)-, monohydrochloride (9CI);1-(5-Isoquinolinesulfonyl)homopiperazine hydrochloride;Fasudilhydrochloride; CAS ...

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    DetailDesc: Keywords 1-(5-Isoquinolinesulfonyl)homopiperazine hydrochloride 5-(1,4-DIAZEPAN-1-YLSULFONYL)ISOQUINOLINE HYDROCHLORIDE (5-ISOQUINOLINESULFONYL)HOMOPIPERAZINE, 2HCL Quick Details ProName: Fasudil Hydrochloride CasNo: 105628-07-7 Molecular Formula: C14H18ClN3O2S Appearance: White...

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  • CAS No. 105628-07-7 (Fasudil hydrochloride )

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    DetailDesc: Identification of 105628-07-7 Name: Fasudil hydrochloride (Related Reference) Molecular Formula: C 14 H 18 ClN 3 O 2 S CAS Registry Number: 105628-07-7 Synonyms: Isoquinoline,5-[(hexahydro-1H-1,4-diazepin-1-yl)sulfonyl]-, hydrochloride (1:1); 1H-1,4-Diazepine,hexahydro-1-(5-isoq...

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    DetailDesc: 【Name】 Fasudil hydrochloride 【CAS】 105628-07-7 【Synonyms】 1-(5-ISOQUINOLINESULFONYL)-1H-HEXAHYDRO-1,4-DIAZEPINE, DIHYDROCHLORIDE 1-(5-ISOQUINOLINESULFONYL)HOMOPIPERAZINE 2HCL 1-(5-ISOQUINOLINESULFONYL)-HOMOPIPERAZINE DIHYDROCHLORIDE 1-(5-ISOQUINOLINESULFONYL)-HOMOPIPERAZIN...

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    DetailDesc: English name: Fasudil Hydrochloride CAS: 105628-07-7 Molecular Formula: C14H19Cl2N3O2S Molecular weight: 364.29100

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References of Fasudil hydrochloride cas 105628-07-7

} Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
monkey LD50 intravenous 20mg/kg (20mg/kg) ? Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 26, Pg. 740, 1995.
mouse LD50 intravenous 67600ug/kg (67.6mg/kg) SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
BEHAVIORAL: STRAUB TAIL
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 20(Suppl,
mouse LD50 oral 274mg/kg (274mg/kg) SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE
BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 20(Suppl,
mouse LD50 subcutaneous 124mg/kg (124mg/kg) SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 20(Suppl,
rat LD50 intravenous 59900ug/kg (59.9mg/kg) SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 20(Suppl,
rat LD50 oral 335mg/kg (335mg/kg) SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE
BEHAVIORAL: TREMOR
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 20(Suppl,
rat LD50 subcutaneous 123mg/kg (123mg/kg) SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE
BEHAVIORAL: TREMOR
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 20(Suppl,