p-Phenylenediamine (cas 106-50-3) Molecular Structure

CAS No. 106-50-3 (p-Phenylenediamine )

Molecular Formula: C6H8N2Molecular Weight: 108.14

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  • CAS No. 106-50-3 (p-Phenylenediamine )

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    DetailDesc: Identification of 106-50-3 Name: p-Phenylenediamine (Related Reference) EINECS: 203-404-7 Molecular Formula: C6H8N2 CAS Registry Number: 106-50-3 Synonyms: 1,4-Diaminobenzene; p-Phenylenediamine 97+ %; 1,4-Phenylenediamine; para Phenylene diamine; P-Phene Diamine; 3,4-Dichlorani...

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    DetailDesc: Product Name: p-Phenylenediamine Synonyms: 1,4-benzendiamine;1,4-Di-aminobenzol;4-phenylenediamine;Aminogen II;BASF Ursol D;basfursold;BASFUrsold,DS;benzene,1,4-diamino- CAS: 106-50-3 MF: C6H8N2 MW: 108.14 EINECS: 203-404-7 Product Categories: VARIOUSAMINE;Intermediates of Dyes ...

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    DetailDesc: p-Phenylenediamine Alias : C.I. 76060; C.I. Developer 13; C.I. Oxidation Base 10; 1,4-Benzenediamine; 1,4-Diaminobenzene; p-Phenylenediamine 97+ %; 1,4-Phenylenediamine; para Phenylene diamine; P-Phene Diamine; 3,4-Dichloraniline; 1,4-benzenediamie; benzene-1,4-diamine; P-PHENYLENE DIAMINE; P-PHENYLENE DIAMINE FLAKE; PDA Structual formul...

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    DetailDesc: Molecular Formula: C6H8N2 Molecular Weight: 108.1411 Appearance: white lump Relative Density: 1.205g /cm ³ Melting Point: 138 -143 ℃ Purity: 99.9% Solubility: Slightly soluble in cold water, soluble in ethanol, ethyl ether, chloroform and benzene. Applications: ① An impor...

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    DetailDesc: Description: Appearance: White flaky (powdery) crystal Content;≥99.9% Uses: Mainly used in producing azo dye and sulfur dye. Alias: C.I. 76060; C.I. Developer 13; C.I. Oxidation Base 10; 1,4-Benzenediamine; 1,4-Diaminobenzene; p-Phenylenediamine 97+ %; 1,4-Phenylenediamine; p...

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    DetailDesc: 1. Product name: PPD (P-Phenylenediamine, Para Phenylenediamine) 2. CAS No.:106-50-3 Appearance: White flake/white powder 3. MF: C6H8N2 Purity : 99.9% Moisture: 0.1% max Melting point: 138centigrade HS Code: 2921519090 3. Use: This compound is used in almost every hair dye on the market, regardless of brand. The darker the colour, usuall...

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References of p-Phenylenediamine cas 106-50-3

} Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
bird - wild LD50 oral 100mg/kg (100mg/kg) ? Archives of Environmental Contamination and Toxicology. Vol. 12, Pg. 355, 1983.
cat LDLo oral 100mg/kg (100mg/kg) CARDIAC: PULSE RATE INCREASE WITHOUT FALL IN BP

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION
Journal of Industrial Hygiene. Vol. 4, Pg. 386, 1923.
dog LDLo intravenous 17mg/kg (17mg/kg) ? Journal of Industrial Hygiene. Vol. 4, Pg. 386, 1923.
dog LDLo subcutaneous 100mg/kg (100mg/kg) BEHAVIORAL: COMA

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS

GASTROINTESTINAL: NAUSEA OR VOMITING
U.S. Public Health Service, Public Health Bulletin. Vol. 271, Pg. 40, 1941.
guinea pig LD50 oral 145mg/kg (145mg/kg) ? Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 53(7), Pg. 62, 1988.
guinea pig LD50 unreported 145mg/kg (145mg/kg) ? Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 31(8), Pg. 46, 1987.
man TDLo oral 71mg/kg (71mg/kg) BEHAVIORAL: MUSCLE WEAKNESS

LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Human Toxicology. Vol. 8, Pg. 345, 1989.
mouse LD50 intraperitoneal 50mg/kg (50mg/kg) ? National Technical Information Service. Vol. AD277-689,
mouse LD50 unreported 331mg/kg (331mg/kg) BRAIN AND COVERINGS: OTHER DEGENERATIVE CHANGES Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 50(6), Pg. 78, 1985.
mouse LDLo oral 100mg/kg (100mg/kg) ? Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 23(5), Pg. 14, 1958.
mouse LDLo subcutaneous 140mg/kg (140mg/kg) ? Journal of the Society of Cosmetic Chemists. Vol. 12, Pg. 500, 1961.
quail LD50 oral 100mg/kg (100mg/kg) ? Archives of Environmental Contamination and Toxicology. Vol. 12, Pg. 355, 1983.
rabbit LDLo intraperitoneal 150mg/kg (150mg/kg) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES Journal of Infectious Diseases. Vol. 42, Pg. 473, 1928.
rabbit LDLo intravenous 300mg/kg (300mg/kg) LUNGS, THORAX, OR RESPIRATION: DYSPNEA

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS
Archives of Internal Medicine. Vol. 36, Pg. 724, 1925.
rabbit LDLo oral 250mg/kg (250mg/kg) CARDIAC: PULSE RATE INCREASE WITHOUT FALL IN BP

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION
Journal of Industrial Hygiene. Vol. 4, Pg. 386, 1923.
rabbit LDLo skin 5gm/kg (5000mg/kg) ? Journal of Toxicology and Environmental Health. Vol. 2, Pg. 657, 1977.
rabbit LDLo subcutaneous 200mg/kg (200mg/kg) CARDIAC: PULSE RATE INCREASE WITHOUT FALL IN BP

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION
Journal of Industrial Hygiene. Vol. 4, Pg. 386, 1923.
rat LC50 inhalation 920mg/m3/4H (920mg/m3) BEHAVIORAL: GENERAL ANESTHETIC

KIDNEY, URETER, AND BLADDER: HEMATURIA

GASTROINTESTINAL: NAUSEA OR VOMITING
National Technical Information Service. Vol. OTS0530403,
rat LD50 intraperitoneal 37mg/kg (37mg/kg) ? Journal of Toxicology and Environmental Health. Vol. 2, Pg. 657, 1977.
rat LD50 oral 80mg/kg (80mg/kg) ? Journal of Toxicology and Environmental Health. Vol. 2, Pg. 657, 1977.
rat LD50 unreported 133mg/kg (133mg/kg) ? Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 31(8), Pg. 46, 1987.
rat LDLo intravenous 50mg/kg (50mg/kg) ? Bulletin de la Societe Royale des Sciences de Liege. Vol. 41, Pg. 302, 1972.
rat LDLo subcutaneous 170mg/kg (170mg/kg) CARDIAC: PULSE RATE INCREASE WITHOUT FALL IN BP

LUNGS, THORAX, OR RESPIRATION: DYSPNEA

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION
Journal of Industrial Hygiene. Vol. 4, Pg. 386, 1923.

Safety

When tested by the United States Environmental Protection Agency, the EPA reported that in rats and mice chronically exposed to PPD in their diet, it simply depressed body weights, but there were no other clinical signs of toxicity, as were observed in several studies.?From?1992 to 2005 years, thirty-one published articles had been investigating a causal association between PPD and cancer . Associations between personal hair dye use and non-Hodgkin's lymphoma, multiple myeloma, acute leukemia, and bladder cancer ?were observed in at least one well-designed study with detailed exposure assessment, but were not consistently observed across studies.?
Hazard Codes:?ToxicT,DangerousN,VeryT+,HarmfulXn
Risk Statements: 23/24/25-36-43-50/53-63-36/37/38-45-40?
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed.?
R36:Irritating to eyes.?
R43:May cause sensitization by skin contact.?
R50/53:Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.?
R63:Possible risk of harm to the unborn child.?
R36/37/38:Irritating to eyes, respiratory system and skin.?
R45:May cause cancer.?
R40:Limited evidence of a carcinogenic effect.
Safety Statements: 28-36/37-45-60-61-28A-24/25-23-53?
S28:After contact with skin, wash immediately with plenty of soap-suds.?
S36/37:Wear suitable protective clothing and gloves.?
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)?
S60:This material and its container must be disposed of as hazardous waste.?
S61:Avoid release to the environment. Refer to special instructions / safety data sheets.?
S24/25:Avoid contact with skin and eyes.?
S23:Do not breathe vapour.?
S53:Avoid exposure - obtain special instructions before use.
RIDADR: UN 1673 6.1/PG 3
WGK Germany: 3
RTECS: SS8050000
F: 8-10-23
HazardClass: 6.1
PackingGroup: III
HS Code: 29215119