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Metformin hydrochloride (cas 1115-70-4) Molecular Structure

Metformin hydrochloride(CAS No. 1115-70-4)

  • Molecular Formula: C4H12ClN5
  • Molecular Weight: 165.62

Identification of 1115-70-4

  • Name:Metformin hydrochloride
  • EINECS:214-230-6
  • Molecular Formula:C4H12ClN5
  • CAS Registry Number:1115-70-4
  • Synonyms: Diaformin;Dialon;Diformin;Diformin Retard;Dimefor;Fornidd;Geamet;Glucomin;Glucomine;Gluconil;Glucophage;Glucophage 850;Glucophage Forte;Glucophage Retard;Glucophage SR;Glufor;Gluformin;Glumeformin;Glumetza;Glumin;Glupermin;Glyceriphage;Glyciphage;Glycon;Metomin;Miformin;N,N-Dimethylbiguanide hydrochloride;N,N-Dimethylbiguanidinium chloride;N1,N1-Dimethylbiguanide hydrochloride;Orabet;Siamformet;Walaphage;Biguanide, 1,1-dimethyl-, monohydrochloride(8CI);Imidodicarbonimidic diamide, N,N-dimethyl-, monohydrochloride (9CI);1,1-Dimethylbiguanide hydrochloride;
  • InChI：InChI=1/C4H11N5.ClH/c1-9(2)4(7)8-3(5)6;/h1-2H3,(H5,5,6,7,8);1H
  • Molecular Structure:Metformin hydrochloride C4H12ClN5 (cas 1115-70-4) Molecular Structure
  • This structure is also available as a 2d Mol file.

Chemical Properties

  • Molecular Weight:165.62
  • Boiling Point:224.1 °C at 760 mmHg
  • Melting Point:223-226℃
  • Flash Point:89.3 °C
  • Biological Activity:Antidiabetic agent; lowers plasma glucose levels and improves insulin sensitivity. Inhibits hepatic gluconeogenesis via activation of the LKB1/AMPK pathway. Displays antiproliferative effects in cancer cell lines.
  • Usage:

    An oral hypoglycemic agent

Safety Data of 1115-70-4

Raw materials
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ChinaDiamond member Hangzhou Dayangchem Co., Ltd.
Dimethyldiguanide hydrochloride
Tel: 86-571-88938639
Fax: 86-571-88938652
Address: B/2601 Fuli Building, 328# WenEr Rd. Hangzhou City 310012 China China
ChinaDiamond member shanghai raise chemical technology Co.,Ltd
RS chemical technology Co.,Ltd is specialized in the synthesis and sales all kinds of chemicals. We have broad experience in the synthesis of intermediates, and every year we provide hundreds of compounds to our customer..
Tel: 86-21-33847795
Fax: 021-33847795
Address: east huaxia road pudong shanghai china China
ChinaDiamond member Shanghai P&T Fine Chemical Co., Ltd.
Founded by a group of veterans from the US biopharmaceutical industry in 2010, P&T is now a leading Shanghai-based CRO company providing drug discovery and development services worldwide. With our technical expertise and..
Tel: 86-21-51601795
Fax: +86-21-33250189
Address: Lane No.36, Zhongke road 2195, Zhangjiang high-tech park, Pudong new area Shanghai, China China
ChinaSilver member Nanjing Chemlin Chemical Co., Ltd.
Purity:98% , 1,1-Dimethylbiguanide hydrochloride 
Tel: 86-25-83697070
Fax: 86-25-83453275
Address: Rm.902 Longyin Plaza, No. 217 Zhongshan Rd.(N) Nanjing 210009,China China
ChinaSilver member NINGBO PANGS CHEM INT'L CO.,LTD.
Our company was established in 1996,through more than 10 years development,our company have already become a very credible and mature supplier,we cooperated with more than 5000 factories in China,and meanwhile,we coopera..
Tel: 86-574-27666845
Address: FLOOR 21 BUILDING 11 XINTIANDI NO.689,SHIJIROAD,NINGBO,CHINA China
China Chifeng Wedge Pharmaceutical Co., Ltd
Purity:BP2009 , Moceular Formula:C4H12CIN5 Moceular Weight:165.6246 CAS No.:1115-70-4 Usage:Lowering blood suger drug STANDARD: BP
Tel: 86-476-8210622
Fax: 86-476-8210827
Address: No.3 Road Wedge, Hongshan Ecnomic Development Zone, Chifeng, Inner Mongolia, China China
China Hangzhou Flying Technology Co., Ltd.
Tel: +86-571-87389059
Fax: +86-571-87389060
Address: Office B-1604,NewYouth Plaza, GongShu Area, HangZhou,ZheJiang,P.R.China China
China Jinan Dingxin Chemical Co.,ltd
Purity:》99% , Metformin Hydrochloride Molecular formula: C 4 H 11 N 5 HCL Molecular weight: 165.63 Characteristics: White crystal or white crystal powder, no smell, easily dissolved in water, dissolved in carbinol, slightly dissolved..
Tel: 86-531-84876767
Fax: 86-0531-84867676
Address: room 1109,fortune square,shanghe county China
China Weihai Disu Pharmaceutical Co., Ltd.
Purity:99.5% , Metformin HCL,CAS No. 1115-70-4 Assay: >99.5%, Pharmaceutical use, diabetes treatment, Lowest price and best quality from CHINA, GMP certified manufacturing.
Tel: 86-631-5991164
Fax: 86-631-5924785
Address: 55 Qilu Avenue, Eco.&Tech. Development Zone China
China WuhanYuanchengTechCo.,Ltd
Alias: Metformin hydrochloride; Metformin; 1, 1 - two methyl guanidine hydrochloride CAS No.: 1115-70-4 MF: C4H11N5 ?HCl MW: 165.63 Packing detail: 25kg/ barrel Physical Character: Metformin hydrochloride is a kind of h..
Tel: 86-27-88730822
Fax: 86-027-68886696
Address: 496 Zhongshan Road ,Wuchang,Wuhan China
China tianjin yaofu chemicals CO., LTD
Purity:99% , CAS#: 1115-70-4 Packing: 25kg/TIN Standard: EP4 BP2002 USP30 Our productions of chemical industry can be devided as follows: 1. Steriods: Triamcinolone Acetonide, Flocinolone Acetonide, Triamcinolone, Dexamethasone Acet..
Tel: 86-22-15620127854
Address: nankai district,tianjin China
China HangZhou Peak Chemical Co.,Ltd
Tel: +86-571-88233073
Fax: +86 571 8542 0855
Address: Rm. 3-502,Building 3 Tucuiyuan,Lakeside Garden,No.176 Wenyi West Road, HangZhou,China China
China Ningbo Fengrui Fine Chemical Ltd.
Tel: +86-574-87720208
Fax: +86-574-87737319
Address: Caihong North Road China
China Wuhan Yuancheng Pharmaceutical Company
Metformin Hydrochloride CAS No.: 1115-70-4 MF: C4H11N5 hCl MW: 165.63 Packing detail: 25kg/ barrel Physical Character: Metformin hydrochloride is a kind of hypoglycemic drugs, is enhanced in patients with type 2 diabete..
Tel: 86-27-88311002
Fax: 86-027-88048077
Address: Zhanshan Road 496 Wuchang District Wuhan China
China Wuxi Hexia Chemical Company
Tel: 0086-510-82740369,82321139
Fax: 0086-510-82729494
Address: 1109, CEPA Center, 16 North JiefangRoad, Wuxi, China China
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References of Metformin hydrochloride

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LD50 intramuscular 200mg/kg (200mg/kg) ? Toxicology and Applied Pharmacology. Vol. 2, Pg. 474, 1960.
guinea pig LD50 intraperitoneal 200mg/kg (200mg/kg) ? Toxicology and Applied Pharmacology. Vol. 2, Pg. 474, 1960.
guinea pig LD50 oral 500mg/kg (500mg/kg) ? Drugs in Japan Vol. -, Pg. 1193, 1990.
guinea pig LD50 subcutaneous 150mg/kg (150mg/kg) ? Drugs in Japan Vol. -, Pg. 1193, 1990.
mouse LD50 intraperitoneal 420mg/kg (420mg/kg) ? Drugs in Japan Vol. 6, Pg. 841, 1982.
mouse LD50 intravenous 180mg/kg (180mg/kg) ? U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#04012,
mouse LD50 oral 1450mg/kg (1450mg/kg) ? Drugs in Japan Vol. 6, Pg. 841, 1982.
mouse LD50 subcutaneous 225mg/kg (225mg/kg) ? Drugs in Japan Vol. -, Pg. 1193, 1990.
rabbit LD50 oral 350mg/kg (350mg/kg) ? Drugs in Japan Vol. -, Pg. 1193, 1990.
rabbit LD50 subcutaneous 150mg/kg (150mg/kg) ? Drugs in Japan Vol. -, Pg. 1193, 1990.
rat LD50 intraperitoneal 500mg/kg (500mg/kg) ? French Demande Patent Document. Vol. #2220256,
rat LD50 oral 1gm/kg (1000mg/kg) ? "Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals", 11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989Vol. 11, Pg. 934, 1989.
rat LD50 subcutaneous 300mg/kg (300mg/kg) ? "Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals", 11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989Vol. 11, Pg. 934, 1989.

Safety

Hazard Codes:?HarmfulXn
Risk Statements: 22-36/38
R22:Harmful if swallowed.?
R36/38:Irritating to eyes and skin.
Safety Statements: 26-36
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S36:Wear suitable protective clothing.
WGK Germany: 3
RTECS: DU1800000

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