Methyl salicylate (cas 119-36-8) Molecular Structure

CAS No. 119-36-8 (Methyl salicylate )

Molecular Formula: C8H8O3Molecular Weight: 152.15

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References of Methyl salicylate cas 119-36-8

} Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
child LDLo oral 228mg/kg (228mg/kg) LUNGS, THORAX, OR RESPIRATION: DYSPNEA

GASTROINTESTINAL: NAUSEA OR VOMITING
American Journal of Diseases of Children. Vol. 69, Pg. 37, 1945.
child LDLo oral 700mg/kg (700mg/kg) PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE)

LUNGS, THORAX, OR RESPIRATION: DYSPNEA

BEHAVIORAL: GENERAL ANESTHETIC
Archives of Disease in Childhood. Vol. 28, Pg. 475, 1953.
dog LD50 oral 2100mg/kg (2100mg/kg) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES

GASTROINTESTINAL: NAUSEA OR VOMITING

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
Food and Cosmetics Toxicology. Vol. 16, Pg. 821, 1978.
dog LDLo subcutaneous 2250mg/kg (2250mg/kg) ? Food and Cosmetics Toxicology. Vol. 16, Pg. 821, 1978.
guinea pig LD50 oral 700mg/kg (700mg/kg) ? "Industrial Hygiene and Toxicology," 2nd ed., Patty, F.A., ed., New York, John Wiley & Sons, Inc., 1958-63Vol. 2, Pg. 1897, 1963.
guinea pig LDLo subcutaneous 1500mg/kg (1500mg/kg) ? FAO Nutrition Meetings Report Series. Vol. 44A, Pg. 63, 1967.
human LDLo oral 506mg/kg (506mg/kg) ? "Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals", 11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989Vol. 11, Pg. 961, 1989.
infant LDLo oral 1480mg/kg (1480mg/kg) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION

GASTROINTESTINAL: NAUSEA OR VOMITING
American Journal of the Medical Sciences. Vol. 193, Pg. 772, 1937.
man LDLo oral 101mg/kg (101mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

GASTROINTESTINAL: NAUSEA OR VOMITING
American Journal of the Medical Sciences. Vol. 193, Pg. 772, 1937.
man LDLo oral 1329mg/kg (1329mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: COMA

BLOOD: HEMORRHAGE
Clinical Toxicology. Vol. 6, Pg. 189, 1973.
man LDLo unreported 522mg/kg (522mg/kg) ? "Poisoning; Toxicology, Symptoms, Treatments," 2nd ed., Arena, J.M., Springfield, IL, C.C. Thomas, 1970Vol. 2, Pg. 73, 1970.
mouse LD50 oral 1110mg/kg (1110mg/kg) ? Journal of Pharmacology and Experimental Therapeutics. Vol. 132, Pg. 207, 1961.
rabbit LD50 oral 1300mg/kg (1300mg/kg) ? Food and Cosmetics Toxicology. Vol. 16, Pg. 821, 1978.
rabbit LDLo subcutaneous 4250mg/kg (4250mg/kg) ? Food and Cosmetics Toxicology. Vol. 16, Pg. 821, 1978.
rat LD50 oral 887mg/kg (887mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) Food and Cosmetics Toxicology. Vol. 2, Pg. 327, 1964.
women LDLo oral 355mg/kg (355mg/kg) BEHAVIORAL: COMA

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION

GASTROINTESTINAL: NAUSEA OR VOMITING
American Journal of the Medical Sciences. Vol. 193, Pg. 772, 1937.
RTECS:? VO4725000

Safety

Hazard Codes:?HarmfulXn
Risk Statements: 22-36/38-36/37/38?
R22:Harmful if swallowed.?
R36/38:Irritating to eyes and skin.?
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36-24/25
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S36:Wear suitable protective clothing.?
S24/25:Avoid contact with skin and eyes.
RIDADR: 3082
WGK Germany: 1
RTECS: VO4725000
F: 8
HazardClass: 6.1(b)
PackingGroup: III
Hazardous Substances Data: 119-36-8(Hazardous Substances Data)