Losartan potassium (cas 124750-99-8) Molecular Structure

CAS No. 124750-99-8 (Losartan potassium )

Molecular Formula: C22H22ClKN6OKMolecular Weight: 461.01

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    DetailDesc:Name: Losartan potassium (Related Reference) Molecular Formula: C22H22ClKN6OK CAS Registry Number: 124750-99-8 Synonyms: Lotim; L-158086; Ocsaar; Losacor; Tenopres; Lortaan; Losaprex; Hyzaar; Niten; DuP 753; Losartan monopotassium salt; MK 954; Lorzaan; Cozaar; Llosartan; Losarta...

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    DetailDesc: English name: Losartan potassium CAS: 124750-99-8 Molecular Formula: C22H22ClKN6O Molecular weight: 461.00100

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References of Losartan potassium cas 124750-99-8

} Toxicity

dog LD oral > 320mg/kg (320mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"

GASTROINTESTINAL: NAUSEA OR VOMITING
Kiso to Rinsho. Clinical Report. Vol. 28, Pg. 3959, 1994.
man TDLo oral 10mg/kg/2W-I (10mg/kg) BLOOD: HEMORRHAGE

SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"
Archives of Internal Medicine. Vol. 158, Pg. 191, 1998.
mouse LDLo intraperitoneal 400mg/kg (400mg/kg) BEHAVIORAL: TREMOR

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Kiso to Rinsho. Clinical Report. Vol. 28, Pg. 3959, 1994.
mouse LDLo oral 1gm/kg (1000mg/kg) SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE

BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

BEHAVIORAL: ATAXIA
Kiso to Rinsho. Clinical Report. Vol. 28, Pg. 3959, 1994.
rat LDLo intraperitoneal 200mg/kg (200mg/kg) BEHAVIORAL: ATAXIA

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Kiso to Rinsho. Clinical Report. Vol. 28, Pg. 3959, 1994.
rat LDLo oral 2gm/kg (2000mg/kg) SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
Kiso to Rinsho. Clinical Report. Vol. 28, Pg. 3959, 1994.
women TDLo oral 1mg/kg/1D-I (1mg/kg) BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS" Archives of Internal Medicine. Vol. 158, Pg. 2063, 1998.

Safety

Hazard Codes:?IrritantXi
Risk Statements: 36/37/38?
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36/37/39?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
RTECS: NI6755100