N,N-Diethyl-3-methylbenzamide (cas 134-62-3) Molecular Structure

CAS No. 134-62-3 (N,N-Diethyl-3-methylbenzamide )

Molecular Formula: C12H17NOMolecular Weight: 191.27

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References of N,N-Diethyl-3-methylbenzamide cas 134-62-3

} Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
child TDLo oral 4750mg/kg (4750mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: STIFFNESS

BEHAVIORAL: COMA
JAMA, Journal of the American Medical Association. Vol. 258, Pg. 1509, 1987.
human TDLo skin 35mg/kg/5D (35mg/kg) SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE" Toxicology and Applied Pharmacology. Vol. 1, Pg. 97, 1959.
mammal (species unspecified) LD50 oral 1800mg/kg (1800mg/kg) ? United States Patent Document. Vol. #3594481,
man LDLo oral 679mg/kg (679mg/kg) ? JAMA, Journal of the American Medical Association. Vol. 258, Pg. 1509, 1987.
mouse LD50 oral 1170mg/kg (1170mg/kg) ? Yakkyoku. Pharmacy. Vol. 36, Pg. 1671, 1985.
mouse LD50 skin 3170uL/kg (3.17mL/kg) ? Yakkyoku. Pharmacy. Vol. 31, Pg. 309, 1980.
rabbit LD50 oral 1584mg/kg (1584mg/kg) ? National Technical Information Service. Vol. AD-A082-131,
rabbit LD50 oral 1584mg/kg (1584mg/kg) ? National Technical Information Service. Vol. AD-A082-131,
rabbit LD50 skin 3180uL/kg (3.18mL/kg) ? Toxicology and Applied Pharmacology. Vol. 28, Pg. 313, 1974.
rabbit LDLo intravenous 75mg/kg (75mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES

BEHAVIORAL: TREMOR
Toxicology and Applied Pharmacology. Vol. 1, Pg. 97, 1959.
rat LC50 inhalation 5950mg/m3 (5950mg/m3) ? National Technical Information Service. Vol. AD-079-960,
rat LD50 oral 1950mg/kg (1950mg/kg) ? Special Publication of the Entomological Society of America. Vol. 78-1, Pg. 53, 1978.
rat LD50 skin 5gm/kg (5000mg/kg) ? Meditsinskaya Parazitologiya i Parazitarnye Bolezni. Medical Parasitology and Parasitic Diseases. Vol. 45, Pg. 65, 1976.
women LDLo oral 950mg/kg (950mg/kg) BEHAVIORAL: COMA

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES

GASTROINTESTINAL: NAUSEA OR VOMITING
JAMA, Journal of the American Medical Association. Vol. 258, Pg. 1509, 1987.
women TDLo oral 300ug/kg (0.3mg/kg) CARDIAC: EKG CHANGES NOT DIAGNOSTIC OF ABOVE

CARDIAC: PULSE RATE INCREASE WITHOUT FALL IN BP

VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION
Journal of Analytical Toxicology. Vol. 19, Pg. 197, 1995.
women TDLo oral 950mg/kg (950mg/kg) SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE

BEHAVIORAL: COMA

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
JAMA, Journal of the American Medical Association. Vol. 258, Pg. 1509, 1987.
?

Safety

Safety Information about N,N-Diethyl-m-toluamide (CAS NO.134-62-3):
Hazard Codes:?HarmfulXn
Risk Statements: 22-36/38-52/53
R22: Harmful if swallowed.?
R36/38: Irritating to eyes and skin.?
R52/53: Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Safety Statements: 61
S21:When using do not smoke.
RIDADR: 2810
WGK Germany: 2
RTECS: XS3675000
HazardClass: 6.1(b)
PackingGroup: III
HS Code: 29242995
Poison by intravenous route. Moderately toxic by ingestion and skin contact. Human systemic effects: coma, convulsions, dermatitis, mydriasis (pupillary dilation), nausea or vomiting, stiffness. An eye and skin irritant. Experimental reproductive effects by skin contact. Mutation data reported. Can cause central nervous system disturbances. A pesticide. DEET is the active ingredient in most commercial insect repellents. When heated to decomposition DIETHYL-m-TOLUAMIDE?(134-62-3) emits toxic fumes of NOx.