Gliclazide (cas 21187-98-4) Molecular Structure

CAS No. 21187-98-4 (Gliclazide )

Molecular Formula: C15H21N3O3SMolecular Weight: 323.41054

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    DetailDesc: CAS: 21187-98-4 Precise quality: 323.13000 Molecular formula: C15H21N3O3S logP: 3.43030 Molecular weight: 323.41100 PSA: 86.89000 Enquiries to check the supplier immediately Using WeChat scan, pay attention to the encyclopedia Basic information about error correction Chinese nam...

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    DetailDesc: Product Name: Gliclazide Synonyms: BENZENESULFONAMIDE, N-[[(HEXAHYDROCYCLOPENTA[C]PYRROL-2(1H)-YL)AMINO]CARBONYL]-4-METHYL-;GLICLAZIDE;GLIMICRON;DIAMICRON;1-(3-azabicyclo[3.3.0]oct-3-yl)-3-p-tolylsulphonylurea;1-(3-AZABICYGCLO[33.0]OCT-3-YL)-3-O-TOLYLSULPHONYLUREA;AKOS NCG1-0056...

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    DetailDesc: Identification of 21187-98-4 Name: Gliclazide (Related Reference) EINECS: 244-260-5 Molecular Formula: C 15 H 21 N 3 O 3 S CAS Registry Number: 21187-98-4 Synonyms: Urea,1-(hexahydrocyclopenta[c]pyrrol-2(1H)-yl)-3-(p-tolylsulfonyl)- (8CI); Cyclopenta[c]pyrrole, benzenesulfonamid...

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    DetailDesc: English name: Gliclazide CAS: 21187-98-4 The molecular formula: C15H21N3O3S Molecular weight: 323.41100

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References of Gliclazide cas 21187-98-4

} Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal > 1gm/kg (1000mg/kg) ? European Journal of Medicinal Chemistry--Chimie Therapeutique. Vol. 17, Pg. 81, 1982.
mouse LD50 intravenous 295mg/kg (295mg/kg) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 8, Pg. 2661, 1980.
mouse LD50 oral 3gm/kg (3000mg/kg) ? Indian Drugs. Vol. 15, Pg. 161, 1978.
mouse LD50 subcutaneous 1034mg/kg (1034mg/kg) SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 8, Pg. 2661, 1980.
rat LD50 intravenous 382mg/kg (382mg/kg) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 8, Pg. 2661, 1980.
rat LD50 oral 3gm/kg (3000mg/kg) ? Indian Drugs. Vol. 15, Pg. 161, 1978.
rat LD50 subcutaneous > 1gm/kg (1000mg/kg) ? Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 8, Pg. 2661, 1980.
women TDLo oral 9600ug/kg/24D (9.6mg/kg) LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA

KIDNEY, URETER, AND BLADDER: URINE VOLUME DECREASED
Internal Medicine. Vol. 33, Pg. 163, 1994.

Safety

Hazard Codes:HarmfulXn,IrritantXi
Risk Statements:21-36/38-46-62-63
R21:Harmful in contact with skin?
R36/38:Irritating to eyes and skin
R46:May cause heritable genetic damage?
R62:Possible risk of impaired fertility?
R63:Possible risk of harm to the unborn child?
Safety Statements:25-26-36/37-53
S25:Avoid contact with eyes?
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36/37:Wear suitable protective clothing and gloves???
S53:Avoid exposure - obtain special instruction before use
WGK Germany:2
RTECS:YT4500000