betamethasone 17-valerate (cas 2152-44-5) Molecular Structure

CAS No. 2152-44-5 (betamethasone 17-valerate )

Molecular Formula: C27H37FO6Molecular Weight: 476.577483

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    DetailDesc: Betamethasone17-valerate 1.Name: Betamethasone17-valerate 2.Molecular Formula: C 27 H 37 FO 6 3.Molecular Mass: 476.58 4.CAS No.: 2152-44-5 5.Package Specification: 25 Kg/Drum 10 Kg/Drum 5 Kg/Drum 6.Quality Specification: EP/USP

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    DetailDesc: EC NO:218-439-3 INCHI:InChI=1/C27H37FO6/c1-5-6-7-23(33)34-27(22(32)15-29)16(2)12-20-19-9-8-17-13-18(30)10-11-24(17,3)26(19,28)21(31)14-25(20,27)4/h10-11,13,16,19-21,29,31H,5-9,12,14-15H2,1-4H3/t16-,19-,20-,21-,24-,25-,26-,27-/m0/s1 MF:C 27 H 37 FO 6 MW:476.58 Synonyms: betamethasone pentanoate;Betamethasone Valerate;1,4-Pregnadiene-11b,17a,21-triol-9a-fluoro-16b-methyl-3,20-dione 17-valerate;9-Fl...

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    DetailDesc: Name Betamethasone 17-valerate Synonyms 1,4-Pregnadiene-11b,17a,21-triol-9a-fluoro-16b-methyl-3,20-dione 17-valerate; 9-Fluoro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 17-valerate Molecular Structure Molecular Formula C 27 H 37 FO 6 Molecular Weight 476.58 CAS Registry Number 2152-44-5 EINECS 218-439-3

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References of betamethasone 17-valerate cas 2152-44-5

} Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 632mg/kg (632mg/kg) ? Shikoku Igaku Zasshi. Shikoku Medical Journal. Vol. 29, Pg. 153, 1973.
mouse LD50 oral 4067mg/kg (4067mg/kg) ? Shikoku Igaku Zasshi. Shikoku Medical Journal. Vol. 29, Pg. 153, 1973.
mouse LD50 subcutaneous 496mg/kg (496mg/kg) ? Shikoku Igaku Zasshi. Shikoku Medical Journal. Vol. 29, Pg. 153, 1973.
rabbit LD50 subcutaneous 61200ug/kg (61.2mg/kg) SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
Oyo Yakuri. Pharmacometrics. Vol. 28, Pg. 687, 1984.
rat LD50 intraperitoneal > 4500mg/kg (4500mg/kg) SKIN AND APPENDAGES (SKIN): HAIR: OTHER Oyo Yakuri. Pharmacometrics. Vol. 28, Pg. 687, 1984.
rat LD50 oral > 3gm/kg (3000mg/kg) SKIN AND APPENDAGES (SKIN): HAIR: OTHER Oyo Yakuri. Pharmacometrics. Vol. 28, Pg. 687, 1984.
rat LDLo subcutaneous 2gm/kg (2000mg/kg) ? Arzneimittel-Forschung. Drug Research. Vol. 27, Pg. 2102, 1977.

Safety

Poison by subcutaneous route. Moderately toxic by intraperitoneal route. Mildly toxic by ingestion. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of F?.
Hazard Codes:?HarmfulXn
Risk Statements: 48?
R48:Danger of serious damage to health by prolonged exposure.
Safety Statements: 22-24/25?
S24/25:Avoid contact with skin and eyes.?
S22:Do not breathe dust.
RIDADR: UN 2811 6.1/PG 3
WGK Germany: 2
RTECS: TU3835000