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Amoxicillin (cas 26787-78-0) Molecular Structure

Amoxicillin(CAS No. 26787-78-0)

  • Molecular Formula: C16H19N3O5S
  • Molecular Weight: 365.4

Identification of 26787-78-0

  • Name:Amoxicillin
  • EINECS:248-003-8
  • Molecular Formula:C16H19N3O5S
  • CAS Registry Number:26787-78-0
  • Synonyms: 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 6-[2-amino-2-(p-hydroxyphenyl)acetamido]-3,3-dimethyl-7-oxo-, D- (8CI);Eupensol;Excillin;Farconcil;Fisamox;Foxolin;Fullcilina;Gemox;Gimalxina;Gomcillin;Gramidil;Grunamox;Hiconcil;Hipen;Histocillin;Hosboral;Imacillin;Imaxilin;Imox;Imoxil;Intermox;Jerramcil;4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,6-[[amino(4-hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-, [2S-[2a,5a,6b(S*)]]-;6-[D-(-)-p-Hydroxy-a-aminobenzyl]penicillin;6-[D-a-Amino-a-(4-hydroxyphenyl)acetamido]penicillanicacid;A-Gram;Actimoxi;Agerpen;Alfamox;Almodan;Alphamox;Amagesen Solutab;Amodex;Amoflux;Amopenixin;Amoxa;Amoxal;Amoxapen;Amoxaren;Amoxi;Amoxi-Mast;Amoxicilina;Amoxidal;Amoxiden;Amoxil;Amoxin;Amoxipen;Amoxtrex;Amoxy;Amoxypen;Ampidroxyl;Ampy-Penyl;Anemol;Anemolin;Apitart;Apo-Amoxi;Ardine;Aspenil;Audumic;BLP1410;BRL 2333;Bactox;Betamox;Bimox;Biomox;Bioxidona;Bioxyllin;Cabermox;Cilamox;Clamox;Clamoxyl;Coamoxin;Comoxyl;D-(-)-a-Amino-p-hydroxybenzyl penicillin;D-2-Amino-2-(4-hydroxyphenyl)acetamidopenicillanic acid;D-Amoxicillin;Delacillin;Efpenix;Efpinex;Eupen;
  • InChI:InChI=1/C16H19N3O5S/c1-16(2)11(15(23)24)19-13(22)10(14(19)25-16)18-12(21)9(17)7-3-5-8(20)6-4-7/h3-6,9-11,14,20H,17H2,1-2H3,(H,18,21)(H,23,24)/t9-,10-,11+,14-/m1/s1
  • Molecular Structure:Amoxicillin C16H19N3O5S (cas 26787-78-0) Molecular Structure
  • This structure is also available as a 2d Mol file.

Chemical Properties

  • Molecular Weight:365.4
  • Density:1.54g/cm3
  • Boiling Point:743.2 °C at 760 mmHg
  • Flash Point:403.3 °C
  • Storage Temperature:2-8°C
  • Solubility:1 g soluble in about 370 ml
  • Appearance:solid
  • Stability:Stable. Incompatible with strong oxidizing agents.
  • Usage:

    Medication.

Safety Data of 26787-78-0

Material Safety Data Sheet(MSDS)

Preparation Products
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Name Amoxicillin trihydrate Molecular Formula C16H19N3O5S Appearance White or alomost white crystalline powder SPECIFICATION Testing terms Standards Results Assay 95.0%~102.0% 99.9% pH 3.5~5.5 4.6 Appearance of solution..
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References of Amoxicillin

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
child TDLo oral 300mg/kg (300mg/kg) KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)"

KIDNEY, URETER, AND BLADDER: HEMATURIA

KIDNEY, URETER, AND BLADDER: OTHER CHANGES IN URINE COMPOSITION
Clinical Pediatrics Vol. 32, Pg. 735, 1993.
child TDLo oral 682mg/kg (682mg/kg) KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)"

KIDNEY, URETER, AND BLADDER: URINE VOLUME DECREASED

KIDNEY, URETER, AND BLADDER: HEMATURIA
Clinical Pediatrics Vol. 32, Pg. 735, 1993.
man TDLo oral 7143ug/kg (7.143mg/kg) SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE" Allergy. Vol. 52(Suppl,
man TDLo oral 40mg/kg/4D (40mg/kg) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"

GASTROINTESTINAL: OTHER CHANGES
Lancet. Vol. 2, Pg. 707, 1978.
mouse LD50 intracrebral > 500mg/kg (500mg/kg) BRAIN AND COVERINGS: RECORDINGS FROM SPECIFIC AREAS OF CNS Chemotherapy Vol. 26, Pg. 196, 1980.
mouse LD50 intraperitoneal 3590mg/kg (3590mg/kg) ? Drugs in Japan Vol. -, Pg. 59, 1990.
mouse LD50 oral > 25gm/kg (25000mg/kg) ? Drugs in Japan Vol. 6, Pg. 38, 1982.
mouse LD50 subcutaneous > 20mg/kg (20mg/kg) ? Drugs in Japan Vol. -, Pg. 59, 1990.
rat LD50 intraperitoneal 2870mg/kg (2870mg/kg) ? Drugs in Japan Vol. -, Pg. 59, 1990.
rat LD50 oral > 15gm/kg (15000mg/kg) ? Drugs in Japan Vol. 6, Pg. 38, 1982.
rat LD50 subcutaneous > 8gm/kg (8000mg/kg) ? Drugs in Japan Vol. -, Pg. 59, 1990.

Safety

Hazard Codes :?HarmfulXn,IrritantXi
Risk Statements : 42/43?
R42/43:May cause sensitization by inhalation and skin contact.
Safety Statements : 22-36/37?
S22:Do not breathe dust.?
S36/37:Wear suitable protective clothing and gloves.
WGK Germany : 2
RTECS : XH8300000