Indapamide (cas 26807-65-8) Molecular Structure

CAS No. 26807-65-8 (Indapamide )

Molecular Formula: C16H16ClN3O3SMolecular Weight: 365.83

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    DetailDesc: Identification of 26807-65-8 Name: Indapamide (Related Reference) EINECS: 248-012-7 Molecular Formula: C 16 H 16 ClN 3 O 3 S CAS Registry Number: 26807-65-8 Synonyms: Lozol (TN); Natrix; Tertensif; 4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-3-yl)-3-sulfamoyl-benzamide; Indapamide...

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References of Indapamide cas 26807-65-8

} Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LD50 intraperitoneal 347mg/kg (347mg/kg) ? Arzneimittel-Forschung. Drug Research. Vol. 25, Pg. 1491, 1975.
guinea pig LD50 intravenous 272mg/kg (272mg/kg) ? Arzneimittel-Forschung. Drug Research. Vol. 25, Pg. 1491, 1975.
guinea pig LD50 oral > 3gm/kg (3000mg/kg) ? Arzneimittel-Forschung. Drug Research. Vol. 25, Pg. 1491, 1975.
mouse LD50 intraperitoneal 410mg/kg (410mg/kg) ? Arzneimittel-Forschung. Drug Research. Vol. 25, Pg. 1491, 1975.
mouse LD50 intravenous 577mg/kg (577mg/kg) ? Arzneimittel-Forschung. Drug Research. Vol. 25, Pg. 1491, 1975.
mouse LD50 oral > 3gm/kg (3000mg/kg) ? Arzneimittel-Forschung. Drug Research. Vol. 25, Pg. 1491, 1975.
mouse LD50 subcutaneous > 10gm/kg (10000mg/kg) ? Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 12, Pg. 1110, 1981.
rabbit LD50 intravenous 337mg/kg (337mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: ATAXIA

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 12, Pg. 1110, 1981.
rat LD50 intraperitoneal 393mg/kg (393mg/kg) ? Arzneimittel-Forschung. Drug Research. Vol. 25, Pg. 1491, 1975.
rat LD50 intravenous 394mg/kg (394mg/kg) ? Arzneimittel-Forschung. Drug Research. Vol. 25, Pg. 1491, 1975.
rat LD50 oral > 3gm/kg (3000mg/kg) ? Arzneimittel-Forschung. Drug Research. Vol. 25, Pg. 1491, 1975.
rat LD50 subcutaneous > 5gm/kg (5000mg/kg) ? Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 12, Pg. 1110, 1981.

Safety

Poison by intravenous and intraperitoneal routes. Experimental teratogenic and reproductive effects. When heated to decomposition it emits toxic fumes of Cl?, SOx, and NOx.