Benzeneethanamine,N-ethyl-a-methyl-3-(trifluoromethyl)-,hydrochloride (1:1) (cas 404-82-0) Molecular Structure

CAS No. 404-82-0 (Benzeneethanamine,N-ethyl-a-methyl-3-(trifluoromethyl)-,hydrochloride (1:1) )

Molecular Formula: C12H16 F3 N . Cl HMolecular Weight: 267.72

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References of Benzeneethanamine,N-ethyl-a-methyl-3-(trifluoromethyl)-,hydrochloride (1:1) cas 404-82-0

} Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LD50 oral 60mg/kg (60mg/kg) BEHAVIORAL: TREMOR

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: REGIDITY
Toxicology and Applied Pharmacology. Vol. 19, Pg. 705, 1971.
child LDLo oral 70mg/kg (70mg/kg) CARDIAC: OTHER CHANGES Clinical Toxicology. Vol. 14, Pg. 97, 1979.
dog LD50 intravenous 23mg/kg (23mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: ALTERATION OF CLASSICAL CONDITIONING

BEHAVIORAL: EXCITEMENT
Toxicology and Applied Pharmacology. Vol. 14, Pg. 182, 1969.
dog LD50 oral 100mg/kg (100mg/kg) BEHAVIORAL: TREMOR

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: REGIDITY
Toxicology and Applied Pharmacology. Vol. 19, Pg. 705, 1971.
guinea pig LD50 intraperitoneal 100mg/kg (100mg/kg) BEHAVIORAL: TREMOR

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: REGIDITY
Toxicology and Applied Pharmacology. Vol. 19, Pg. 705, 1971.
human TDLo oral 7mg/kg (7mg/kg) SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE

BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)

GASTROINTESTINAL: NAUSEA OR VOMITING
British Medical Journal. Vol. 1, Pg. 740, 1967.
mouse LD50 intraperitoneal 92mg/kg (92mg/kg) BEHAVIORAL: FOOD INTAKE (ANIMAL)

BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)
Arzneimittel-Forschung. Drug Research. Vol. 28, Pg. 1561, 1978.
mouse LD50 intravenous 90mg/kg (90mg/kg) BEHAVIORAL: TREMOR

BEHAVIORAL: REGIDITY

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Toxicology and Applied Pharmacology. Vol. 19, Pg. 705, 1971.
mouse LD50 oral 170mg/kg (170mg/kg)   Therapie. Vol. 20, Pg. 297, 1965.
rabbit LD50 oral 50mg/kg (50mg/kg) BEHAVIORAL: TREMOR

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: REGIDITY
Toxicology and Applied Pharmacology. Vol. 19, Pg. 705, 1971.
rat LD50 intraperitoneal 90mg/kg (90mg/kg) BEHAVIORAL: TREMOR

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: REGIDITY
Toxicology and Applied Pharmacology. Vol. 19, Pg. 705, 1971.
rat LD50 oral 69mg/kg (69mg/kg) BEHAVIORAL: FLUID INTAKE Toxicology and Applied Pharmacology. Vol. 14, Pg. 182, 1969.
women TDLo oral 36mg/kg (36mg/kg) SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE

BEHAVIORAL: SLEEP

BEHAVIORAL: TREMOR
Journal of Toxicology, Clinical Toxicology. Vol. 33, Pg. 161, 1995.

Safety

Poison by ingestion, intravenous, and intraperitoneal routes. Human systemic effects by ingestion: mydriasis, change in motor activity, nausea. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits very toxic fumes of F, NOx, and HCl.
Hazard Codes of Fenfluramine hydrochloride (CAS NO.404-82-0): ToxicT
Risk Statements: 25 
R25: Toxic if swallowed.
Safety Statements: 7-16-36/37-45
S7: Keep container tightly closed. 
S16: Keep away from sources of ignition. 
S36/37: Wear suitable protective clothing and gloves. 
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR: UN 2811 6.1/PG 3
WGK Germany: 3
RTECS: DA0295500
HazardClass: 6.1(b)
PackingGroup: III