L(+)-Ascorbic acid (cas 50-81-7) Molecular Structure

CAS No. 50-81-7 (L(+)-Ascorbic acid )

Molecular Formula: C6H8O6Molecular Weight: 176.12

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    DetailDesc: Item Index Molecular Formula C6H8O6 Molecular weight 176.12 Specification USP/CP/EP Appearance white to slightly yellow Density 1.65 g/cm3 Melting point 190-194 °C (dec.) Specific rotation 20.5 º (C=10,H2O) Refractive index 21 ° (C=10, H2O) Solubility( in water), at...

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    DetailDesc: Product Identification.: Product name: Ascorbic acid Synonyms: L-Ascorbic acid; vitamin C; VC Molecular Formula: C 6 H 8 O 6 Molecular Weight: 176.12 CAS No: 50-81-7 Quality standard.: ( see table ) The quality conforms to BP/USP. Ascorbic Acid Quality standard Item Index Charac...

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    DetailDesc:176.12,C6H8O6

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    DetailDesc: Specification ITEM STANDARD Appearance White or almost white crystal or crystalline powder Identification Positive Melting point 191 ℃ ~ 192℃ pH (5%, w/v) 2.2 ~ 2.5 pH (2%,w/v) 2.4 ~ 2.8 Specific optical rotation +20.5° ~ +21.5° Clarity of solution Clear Heavy metals =...

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References of L(+)-Ascorbic acid cas 50-81-7

} Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
man TDLo intravenous 2300mg/kg/2D (2300mg/kg) BLOOD: OXIDANT RELATED (GPD DEFICIENT) ANEMIA Annals of Internal Medicine. Vol. 82, Pg. 810, 1975.
mouse LD50 intraperitoneal 643mg/kg (643mg/kg) ? Progress in Mutation Research. Vol. 1, Pg. 682, 1981.
mouse LD50 intravenous 518mg/kg (518mg/kg) ? Research Progress in Organic-Biological and Medicinal Chemistry. Vol. 2, Pg. 269, 1970.
mouse LD50 oral 3367mg/kg (3367mg/kg) ? National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program. Vol. JAN1986,
rat LD50 intravenous > 4gm/kg (4000mg/kg) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Oyo Yakuri. Pharmacometrics. Vol. 12, Pg. 131, 1976.
rat LD50 oral 11900mg/kg (11900mg/kg) SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
Oyo Yakuri. Pharmacometrics. Vol. 12, Pg. 131, 1976.
rat LD50 subcutaneous > 10gm/kg (10000mg/kg) ? Oyo Yakuri. Pharmacometrics. Vol. 12, Pg. 131, 1976.
women LDLo intravenous 900mg/kg (900mg/kg) KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)" Archives of Internal Medicine. Vol. 145, Pg. 950, 1985.

Safety

Hazard Codes of?L-Ascorbate (CAS NO.50-81-7):?Xn
Risk Statements: 20/21/22-36/37/38?
R20/21/22: Harmful by inhalation, in contact with skin and if swallowed.?
R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements: 24/25-36-26?
S24/25: Avoid contact with skin and eyes.?
S36: Wear suitable protective clothing.?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany: 1
RTECS: CI7650000
HS Code: 29362700