S-budesonide (cas 51333-22-3) Molecular Structure

CAS No. 51333-22-3 (S-budesonide )

Molecular Formula: C25H34O6Molecular Weight: 430.54

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    DetailDesc: Budesonide Formula: C25H34O6 Synonyms: Budeson;Respules;16-alpha,17-alpha- Molecular Weight: 430.59 EINECS: 257-139-7 CAS No.: 51333-22-3 Melting Point: 221-232 °C (dec.) Boiling Point: 599.7 °C at 760 mmHg Appearance: white crystalline powder Storage: Room temperature A...

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    DetailDesc: CAS: 51333-22-3 Precise quality: 430.23600 Molecular formula: C25H34O6 logP: 2.71680 Molecular weight: 430.53400 PSA: 93.06000 Enquiries to check the supplier immediately Using WeChat scan, pay attention to the encyclopedia Basic information about error correction Chinese name: ...

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References of S-budesonide cas 51333-22-3

} Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 subcutaneous 173mg/kg (173mg/kg) GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"

BLOOD: CHANGES IN SPLEEN
Kiso to Rinsho. Clinical Report. Vol. 19, Pg. 4377, 1985.
man TCLo inhalation 34ug/kg (0.034mg/kg) SKIN AND APPENDAGES (SKIN): "DERMATITIS, ALLERGIC: AFTER SYSTEMIC EXPOSURE" Australian and New Zealand Journal of Medicine. Vol. 22, Pg. 511, 1992.
mouse LD50 intraperitoneal 179mg/kg (179mg/kg) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Kiso to Rinsho. Clinical Report. Vol. 19, Pg. 4377, 1985.
mouse LD50 intravenous 124mg/kg (124mg/kg) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Kiso to Rinsho. Clinical Report. Vol. 19, Pg. 4377, 1985.
mouse LD50 oral 4750mg/kg (4750mg/kg) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Kiso to Rinsho. Clinical Report. Vol. 19, Pg. 4377, 1985.
mouse LD50 subcutaneous 53600ug/kg (53.6mg/kg) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Kiso to Rinsho. Clinical Report. Vol. 19, Pg. 4377, 1985.
rat LD50 intraperitoneal 138mg/kg (138mg/kg) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

BLOOD: CHANGES IN SPLEEN
Kiso to Rinsho. Clinical Report. Vol. 19, Pg. 4377, 1985.
rat LD50 intravenous 98900ug/kg (98.9mg/kg) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Kiso to Rinsho. Clinical Report. Vol. 19, Pg. 4377, 1985.
rat LD50 oral > 3200mg/kg (3200mg/kg) ? Kiso to Rinsho. Clinical Report. Vol. 19, Pg. 4377, 1985.
rat LD50 subcutaneous 58400ug/kg (58.4mg/kg) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

BLOOD: CHANGES IN SPLEEN
Kiso to Rinsho. Clinical Report. Vol. 19, Pg. 4377, 1985.

Safety

Hazard Codes:?HarmfulXn
Risk Statements: 40-36/37/38-20/21/22?
R40: Limited evidence of a carcinogenic effect.?
R36/37/38: Irritating to eyes, respiratory system and skin.?
R20/21/22: Harmful by inhalation, in contact with skin and if swallowed.
Safety Statements: 22-36-26?
S22: Do not breathe dust.?
S36: Wear suitable protective clothing.?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany: 3
RTECS: TU3723000
Poison by subcutaneous, intravenous, and intraperitoneal routes. Moderately toxic by ingestion. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits acrid smoke and fumes.