5-Isobenzofurancarbonitrile,1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro- (cas 59729-33-8) Molecular Structure

CAS No. 59729-33-8 (5-Isobenzofurancarbonitrile,1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro- )

Molecular Formula: C20H21FN2OMolecular Weight: 324.391943

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References of 5-Isobenzofurancarbonitrile,1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro- cas 59729-33-8

} Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
human TDLo oral 4571ug/kg/8D- (4.571mg/kg) BEHAVIORAL: SLEEP

BEHAVIORAL: HEADACHE

GASTROINTESTINAL: NAUSEA OR VOMITING
Human Psychopharmacology. Vol. 12, Pg. 119, 1997.
man LDLo oral 56mg/kg (56mg/kg) CARDIAC: ARRHYTHMIAS (INCLUDING CHANGES IN CONDUCTION) Lancet. Vol. 348, Pg. 339, 1996.
mouse LD50 intraperitoneal 179mg/kg (179mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) Journal of Pharmacy and Pharmacology. Vol. 49, Pg. 1019, 1997.

Safety

RIDADR: 3249
HazardClass: 6.1(b)
PackingGroup: III