Benzoic acid (cas 65-85-0) Molecular Structure

CAS No. 65-85-0 (Benzoic acid )

Molecular Formula: C7H6O2Molecular Weight: 122.12

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References of Benzoic acid cas 65-85-0

} Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
frog LDLo subcutaneous 100mg/kg (100mg/kg)   "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 5, Pg. 23, 1959.
guinea pig LDLo intraperitoneal 1400mg/kg (1400mg/kg)   "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 5, Pg. 23, 1959.
guinea pig LDLo oral 2gm/kg (2000mg/kg)   Muenchener Medicinische Wochenschrift. Vol. 77, Pg. 13, 1930.
human TDLo skin 6mg/kg (6mg/kg) LUNGS, THORAX, OR RESPIRATION: DYSPNEA

SKIN AND APPENDAGES (SKIN): "DERMATITIS, ALLERGIC: AFTER SYSTEMIC EXPOSURE"
Journal of Allergy. Vol. 16, Pg. 195, 1945.
man LDLo oral 500mg/kg (500mg/kg)   Food and Cosmetics Toxicology. Vol. 17, Pg. 715, 1979.
mouse LD50 intraperitoneal 1460mg/kg (1460mg/kg)   Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales. Vol. 160, Pg. 1097, 1966.
mouse LD50 oral 1940mg/kg (1940mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION

GASTROINTESTINAL: OTHER CHANGES
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 15, Pg. 359, 1984.
rabbit LD50 skin > 10gm/kg (10000mg/kg)   BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. Vol. 28-4/1973,
rabbit LDLo oral 2gm/kg (2000mg/kg)   "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 5, Pg. 23, 1959.
rabbit LDLo subcutaneous 2gm/kg (2000mg/kg)   "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 5, Pg. 23, 1959.
rat LC50 inhalation > 26mg/m3/1H (26mg/m3) SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. Vol. 28-4/1973,
rat LD50 intraperitoneal 1600mg/kg (1600mg/kg)   Bollettino Chimico Farmaceutico. Vol. 112, Pg. 53, 1973.
rat LD50 intravenous 1700mg/kg (1700mg/kg)   Acta Physiologica Polonica. Vol. 12, Pg. 173, 1961.
rat LD50 oral 1700mg/kg (1700mg/kg)   International Polymer Science and Technology. Vol. 3, Pg. 93, 1976.

Safety

Hazard Codes: Xn,T
Risk Statements: 22-36-42/43-36/37/38-40-63-43-23/24/25-45
22:  Harmful if swallowed 
36:  Irritating to the eyes 
42/43:  May cause sensitization by inhalation and skin contact 
36/37/38:  Irritating to eyes, respiratory system and skin 
40:  Limited evidence of a carcinogenic effect 
63:  In case of accident by inhalation, remove casualty to fresh air and keep at rest 
43:  In case of fire, use ... (indicate in the space the precise type of fire-fighting equipment. If water increases the risk add - Never use water) 
23/24/25:  Toxic by inhalation, in contact with skin and if swallowed 
45:  May cause cancer 
41:  Risk of serious damage to eyes 
37/38:  Irritating to respiratory system and skin 
20/21/22:  Harmful by inhalation, in contact with skin and if swallowed
Safety Statements: 26-45-37/39-24-22-36/37-24/25-23-53
26:  In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 
45:  In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) 
37/39:  Wear suitable gloves and eye/face protection 
24:  Avoid contact with skin 
22:  Do not breathe dust 
36/37:  Wear suitable protective clothing and gloves 
24/25:  Avoid contact with skin and eyes 
23:  Do not breathe gas/fumes/vapor/spray (appropriate wording to be specified by the manufacturer) 
53:  Avoid exposure - obtain special instruction before use 
36:  Wear suitable protective clothing
RIDADR: UN 3077 9/PG 3
WGK Germany: 1
RTECS: DG0875000
F: 21
Hazard Note: Harmful