Retinol (cas 68-26-8) Molecular Structure

CAS No. 68-26-8 (Retinol )

Molecular Formula: C20H30OMolecular Weight: 286.452

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    DetailDesc:Name: Retinol Synonyms: Retinol,all-trans- (8CI);2,4,6,8-Nonatetraen-1-ol, 3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-,(all-E)-;A-Mulsal;A-Vi-Pel;Acon;Agiolan;Alcovit A;Alphalin;Anatola;Anti-Infective vitamin;Aoral;Apostavit;Aquasol A Parenteral;Avibon;Avitol;Axerophthol;...

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    DetailDesc: Retinol(Vitamin A) Synonyms:Agiolan;Alcovit A;Alphalin;Anatola;Anti-Infective vitamin;Aoral;Apostavit;Aquasol A Parenteral;Avibon;Avitol;Axerophthol;trans-VitaminA alcohol CAS:68-26-8 Formula:C20H30O Molecular Weight:286.50 EINECS:200-683-7 Assay:99% by HPLC Appearance:Retinol i...

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References of Retinol cas 68-26-8

} Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
child TDLo oral 912ku/kg/2Y-I (912000iu/kg) SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE

LIVER: OTHER CHANGES

SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"
New England Journal of Medicine. Vol. 294, Pg. 805, 1976.
child TDLo oral 5475ku/kg/1Y- (5475000iu/kg) LUNGS, THORAX, OR RESPIRATION: PLEURAL EFFUSION

GASTROINTESTINAL: OTHER CHANGES

MUSCULOSKELETAL: OTHER CHANGES
Clinical Pediatrics Vol. 21, Pg. 435, 1982.
infant LDLo oral 442ku/kg/11D- (442000iu/kg) BEHAVIORAL: ANOREXIA (HUMAN

BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)

KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)"
Archives of Pathology and Laboratory Medicine. Vol. 108, Pg. 838, 1984.
man TDLo oral 1217ku/kg/1Y- (1217000iu/kg) LIVER: "HEPATITIS, FIBROUS (CIRRHOSIS, POST-NECROTIC SCARRING)"

BLOOD: HEMORRHAGE

BLOOD: CHANGES IN SPLEEN
Liver Annual. Vol. 12, Pg. 381, 1992.
mouse LD50 intraperitoneal 1510mg/kg (1510mg/kg) ? Journal of the American Academy of Dermatology. Vol. 6, Pg. 652, 1982.
mouse LD50 oral 1510mg/kg (1510mg/kg) ? "The Retinoids, Vol.2," Sporn, M.B., et al., eds., New York, Academic Press, Inc., 1984Vol. 2, Pg. 287, 1984.
rat LD50 oral 2gm/kg (2000mg/kg) ? Acta Dermato-Venereologica, Supplementum. Vol. 74, Pg. 29, 1975.
women TDLo oral 91000iu/kg/26 (91000iu/kg) BEHAVIORAL: ANOREXIA (HUMAN

LIVER: "JAUNDICE, OTHER OR UNCLASSIFIED"

SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"
American Journal of Medicine. Vol. 97, Pg. 523, 1994.

Safety

Moderately toxic by ingestion. Human teratogenic effects by ingestion: developmental abnormalities of the craniofacial area and urogenital system. An experimental teratogen. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes.
Hazard Codes:?XnNF
Risk Statements: 22-38-67-65-62-51/53-48/20-11?
R22: Harmful if swallowed
R38: Irritating to skin
R67: Vapours may cause drowsiness and dizziness
R65: Harmful: may cause lung damage if swallowed
R62: Risk of impaired fertility
R51/53: Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment
R48/20: Harmful: danger of serious damage to health by prolonged exposure through inhalation
R11: Highly flammable
Safety Statements: 36/37-61-62?
S36/37: Wear suitable protective clothing and gloves
S61: Avoid release to the environment. Refer to special instructions / safety data sheets
S62: If swallowed, do not induce vomitting; seek medical advice immediately and show this container or label
RIDADR: UN 1208 3/PG 2
WGK Germany: 3
RTECS: VH6750000
F: 8-10-16-23?
F 8: Photosensitive
F 10: Keep under argon
F 16: Decomposes easily
F 23: Sensitive to air