3-Isoxazolidinone,4-amino-, (4R)- (cas 68-41-7) Molecular Structure

CAS No. 68-41-7 (3-Isoxazolidinone,4-amino-, (4R)- )

Molecular Formula: C3H6N2O2Molecular Weight: 102.09

Related Products Information

Page:1/6 < >
Contact Supplier
  • D-CycloserineCAS NO.: 68-41-7

    Updatetime:Oct 20 2017

    FOB Price:5600 USD/Kilogram Purity:99% Min. Order:1/Kilogram Supply Ability:10 Day/Metric Ton

    DetailDesc: CAS: 68-41-7 Precise quality: 102.04300 Molecular formula: C3H6N2O2 logP: 0.59580 Molecular weight: 102.09200 PSA: 64.35000 Enquiries to check the supplier immediately Using WeChat scan, pay attention to the encyclopedia The basic information Chinese name: D - ring serine Chines...

    Tel:86-153-73023168
    Address:NO.18TH VANKE NORTH STREET,CHENGHUA DISTRICT, CHENGDU CITY , SICHUAN PROVINCE
    chengdu yancey import& export trade co.,ltd

    Diamond member Diamond member Audited Supplier

    Country/Region:China

    Business Type: Trading Company

    Contact Supplier SkypeSkype

  • 3-Isoxazolidinone,4-amino-, (4R)- CAS 68-41-7

    Updatetime:Oct 20 2017

    FOB Price:1 USD/Gram Purity:99% Min. Order:1/Gram Supply Ability:100 Day/Kilogram

    DetailDesc: Name: Colesevelam hydrochloride Synonyms: 2-Propen-1-amine polymer with (chloromethyl)oxirane, N-2-propenyl-1-decanamine and N,N,N-trimethyl-6-(2-propenylamino)-1-hexanaminium chloride hydrochloride CAS Registry number: 182815-44-7 Molecular Formula: (C13H27N)n.(C12H27ClN2)n.(C3...

    Tel:86-27-83214668
    Address:East and West Lake District, Wuhan, China
    Hubei XinRunde Chemical Co., Ltd

    Diamond member Diamond member Audited Supplier

    Country/Region:China

    Business Type: Manufacturer

    Contact Supplier

  • D-Cycloserine

    Updatetime:Oct 20 2017

    FOB Price:3 USD/Kilogram Purity:95%, 99% Min. Order:1/Kilogram Supply Ability:50 Year/Metric Ton

    DetailDesc:Name: 3-Isoxazolidinone,4-amino-, (4R)- Synonyms: 3-Isoxazolidinone,4-amino-, (+)- (8CI);3-Isoxazolidinone, 4-amino-, (R)-;(+)-Cycloserine;(4R)-4-Amino-3-isoxazolidinone;(R)-4-Amino-3-isoxazolidinone;(R)-Cycloserine;Cyclo-D-serine;Cycloserine;D-4-Amino-3-isoxazolidinone;D-4-Amino...

    Tel:86-571-88938639
    Address:9/F Unit 2 ChangdiTorch Building, 259 #WenSan Road
    Hangzhou Dayangchem Co., Ltd.

    Diamond member Diamond member Audited Supplier

    Country/Region:China

    Business Type: Manufacturer

    Contact Supplier MSNMSN SkypeSkype

  • D-cycloserine

    Updatetime:Oct 20 2017

    Purity:97%

    DetailDesc:organic latermediates

    Tel:86-312-18103315327
    Address:east huaxia road pudong shanghai china
    shijiazhuang guizheng trade co.,ltd

    Diamond member Diamond member Audited Supplier

    Country/Region:China

    Business Type: Trading Company

    Contact Supplier

  • D-Cycloserine

    Updatetime:Oct 19 2017

    Purity:98.0%~101.0% Min. Order:0/Metric Ton Supply Ability:Metric Day/Ton

    DetailDesc: Keywords D-Cycloserine China D-Cycloserine seller D-Cycloserine low price Quick Details ProName: D-Cycloserine CasNo: 68-41-7 Appearance: white crystalline powder DeliveryTime: in 10 days after payment PackAge: as request ProductionCapacity: Metric Ton/Day Purity: 98.0%~101.0% S...

    Tel:86-311-13292230735
    Address:jianhua street
    FORT ST BIOLOGICAL TECHNOLOGY LIMITED

    Diamond member Diamond member Audited Supplier

    Country/Region:China

    Business Type: Trading Company

    Contact Supplier SkypeSkype

  • D-Cycloserine

    Updatetime:Oct 19 2017

    Purity:99% Min. Order:1/Kilogram Supply Ability:1-100 Year/Metric Ton

    DetailDesc:D-Cycloserine CAS:68-41-7 EINECS NO.:200-688-4 M.F.:C3H7N2O2 M.W.:103.0993

    Tel:0086-27-59207850
    Address:A2705,Dong Yi Shi Qu,129# XinHua Road
    Wuhan Fortuna Chemical Co., Ltd.

    Diamond member Diamond member Audited Supplier

    Country/Region:China

    Business Type: Manufacturer

    Contact Supplier MSNMSN SkypeSkype

  • D-cycloserine

    Updatetime:Oct 09 2017

    DetailDesc:Name: 3-Isoxazolidinone,4-amino-, (4R)- Synonyms: 3-Isoxazolidinone,4-amino-, (+)- (8CI);3-Isoxazolidinone, 4-amino-, (R)-;(+)-Cycloserine;(4R)-4-Amino-3-isoxazolidinone;(R)-4-Amino-3-isoxazolidinone;(R)-Cycloserine;Cyclo-D-serine;Cycloserine;D-4-Amino-3-isoxazolidinone;D-4-Amino-3-isoxazolidone;D-CS;Farmiserina;Micoserina;Miroseryn;NSC 154851;Novoserin;Orientomycin;Oxamycin;Seromycin;Tisomycin;Wa...

    Tel:86-531-58897029
    Address:No.2350,Kaituo Road,High-tech Development Zone,Jinan,Shandong,China
    Jinan Chenghui Shuangda Chemical Co., Ltd

    Diamond member Diamond member Audited Supplier

    Country/Region:China

    Business Type: Manufacturer

    Contact Supplier

  • Cycloserine

    Updatetime:Sep 28 2017

    FOB Price:2300 USD/Metric Ton Purity:99% Min. Order:1/Metric Ton Supply Ability:2000 Quarter/Metric Ton

    DetailDesc: Quick Details CAS No.: 68-41-7" style="margin: 0px; padding: 0px; border: 0px; font-family: inherit; font-size: inherit; font-style: inherit; font-variant: inherit; font-weight: inherit; line-height: inherit; vertical-align: baseline; overflow: hidden; word-wrap: norma...

    Tel:86-181-32289416
    Address:xiaodianqu
    Shanxi KingWayTechnology Co.,Ltd

    Diamond member Diamond member Audited Supplier

    Country/Region:China

    Business Type: Manufacturer

    Contact Supplier

  • D-Cycloserine

    Updatetime:Sep 20 2017

    Purity:98% Min. Order:1/Gram Supply Ability:500 Month/Kilogram

    DetailDesc: D-Cycloserine (CAS: 68-41-7) is an amino acid with an unusual structure. D-Cycloserine Attribute Molecular Formula C3H7N2O2 Molecular Weight 103.0993 Melting point 147℃ Water solubility SOLUBLE D-Cycloserine Molecular Formula Synonyms: Cycloserine; D-Cycloserine, STREPTOMYCES O...

    Tel:86-574-89212210
    Address:Guangbo Center Office 2002, YinXianDaDao 1357
    MOSINTER GROUP LIMITED

    Diamond member Diamond member Audited Supplier

    Country/Region:China

    Business Type: Manufacturer

    Contact Supplier SkypeSkype

  • D-Cycloserine

    Updatetime:Aug 04 2017

    Purity:99%

    DetailDesc:White to pale yellow cryst. powder

    Tel:86-311-66600578
    Address:C-2103 Wonder Business Square, 15 Yuhua West Rd.
    AOPHARM

    Diamond member Diamond member Audited Supplier

    Country/Region:China

    Business Type: Manufacturer

    Contact Supplier MSNMSN SkypeSkype

  • 3-Isoxazolidinone,4-amino-, (4R)-

    Updatetime:Jul 18 2017

    FOB Price:100 USD/Kilogram Purity:99% Min. Order:1/Kilogram Supply Ability:100 Month/Kilogram

    DetailDesc:APIs Pharmaceutical Adjuvant Biochemicals & Biotech products

    Tel:86-571-85829152
    Address:Room 606, Fuyi Center, #298 Quanfuqiao Road, Jiang
    Jinlan Pharm-Drugs Technology Co., Limited

    Diamond member Diamond member Audited Supplier

    Country/Region:China

    Business Type: Manufacturer

    Contact Supplier SkypeSkype

  • D-Cycloserine

    Updatetime:Jun 19 2017

    Purity:97.00% Min. Order:1/Gram Supply Ability:10 Month/Kilogram

    DetailDesc:CAS No.:68-41-7;Name:D-Cycloserine;Assay:0.97;appearance:White to light yellow crystalline powder ;Brief Introduction:intermediates, drug discovery

    Tel:86-25-83697070
    Address:Rm.902 Longyin Plaza, No. 217 Zhongshan Rd.(N) Nanjing 210009,China
    Nanjing Chemlin Chemical Co., Ltd.

    Diamond member Diamond member Audited Supplier

    Country/Region:China

    Business Type: Manufacturer

    Contact Supplier MSNMSN SkypeSkype

  • D-Cycloserine

    Updatetime:Jun 06 2017

    Purity:contact us for more details about D-Cycloserine, CAS:68-41-7

    DetailDesc:FINETECH INDUSTRY LIMITED is a LONDON based CRO company providing drug discovery & development services to worldwide clients. FINETECH INDUSTRY LIMITED supplies the D-Cycloserine, CAS:68-41-7 with the most competitive price and the best quality. We can offer efficient service and the best package.Welcome the enquiries & orders around the ...

    Tel:86-27-87465837
    Address:chukang Road, Wuhan, Hubei 430073,
    Finetech Industry limited.

    Diamond member Diamond member Audited Supplier

    Country/Region:China

    Business Type: Manufacturer

    Contact Supplier

  • D-Cycloserine

    Updatetime:Jun 28 2017

    FOB Price:1 USD/Gram Purity:98% Min. Order:1/Gram Supply Ability:100 Month/Kilogram

    DetailDesc:We could receive custom synthesis according to your requirements from lab scale to commercial scale

    Tel:86-21-60542966
    Address:Lane 299 Bisheng Rd,Pudong District
    Hui Chem Company Limited

    Audited Supplier

    Country/Region:China

    Business Type: Manufacturer

    Contact Supplier SkypeSkype

  • D-cycloserine

    Updatetime:Jun 14 2017

    FOB Price:800 USD/Kilogram Purity:99% Min. Order:1/Kilogram Supply Ability:1000 Quarter/Kilogram

    DetailDesc: Jinan Jianfeng Chemical Co.Ltd is a leading research-driven family-managed pharmaceutical company. In the principle of “ Quality Oriented ” , Jianfeng passed the certification of ISO9001:2008 Quality Management System. The products meet USP, EP, JP and CP standards a...

    Tel:86-531-88110457
    Address:Huaneng Road, Licheng District, Jinan City, Shandong Pro., China
    Jinan Jianfeng Chemical Co., Ltd

    Audited Supplier

    Country/Region:China

    Business Type: Manufacturer

    Contact Supplier

  • D-Cycloserine

    Updatetime:May 24 2017

    Purity:98.00% Min. Order:10/Gram Supply Ability:800 Month/Kilogram

    DetailDesc: Appearance: white to off-white powder Molecular Weight: 102.09 Density: 1.278 g/cm3 Boiling Point: 267 Melting Point: 147℃ Alpha: 111 o (C=5, 2N NAOH) Storage Temperature: 20°C Solubility: SOLUBLE IN WATER Stability: Stable under normal temperatures and pressures. Usage: In...

    Tel:86-27-88660577
    Address:27th FL.shuian international masion Bldg.1,Heping Ave.wuhan city
    Wuhan Haizheng Industry & Trade Development Co. Ltd

    Audited Supplier

    Country/Region:China

    Business Type: Manufacturer

    Contact Supplier MSNMSN SkypeSkype

  • D-4-Amino-3-isoxazolidinone

    Updatetime:Dec 06 2016

    Purity:98% Min. Order:1/Kilogram Supply Ability:up to kgs Month/Kilogram

    DetailDesc:102.09,C3H6N2O2

    Tel:86-571-85586718
    Address:Joinhands Science Park, No.4028,Nanhuan Road,
    Capot Chemical Co., Ltd.

    Audited Supplier

    Country/Region:China

    Business Type: Manufacturer

    Contact Supplier MSNMSN

  • 99% D-Cycloserine 68-41-7 Factory Amino Acid

    Updatetime:Sep 29 2016

    FOB Price:1 USD/Kilogram Purity:99% Min. Order:10/Kilogram Supply Ability:50000 Quarter/Kilogram

    DetailDesc: Product Name: D-Cycloserine Synonyms: CYCLOSERINE;D-CYCLOSERINE;D-CYCLOSERINE, STREPTOMYCES ORCHIDACEUS;D-4-AMINO-3-ISOXAZOLIDINONE;(R)-(+)-CYCLOSERINE;(R)-4-AMINO-ISOXAZOLIDIN-3-ONE;(R)-4-AMINO-3-ISOXAZOLIDINONE;R(+)-4-AMINO-3-ISOXAZOLIDINONE CAS: 68-41-7 MF: C3H6N2O2 MW: 102.0...

    Tel:86-27-59212929
    Address:daijiashan 45,jiangan economic departmen zone,wuhan,hubei,China
    Wuhan Dahua Weiye Pharmaceutical Co.,Ltd

    Audited Supplier

    Country/Region:China

    Business Type: Manufacturer

    Contact Supplier SkypeSkype

  • D-Cycloserin

    Updatetime:Sep 22 2016

    Tel:86-21-61723543
    Address:Room508, Building1, No.88 CaiLun Road Zhangjiang H

    Introduction:FoundedbyagroupofveteransfromtheUSbiopharmaceuticalindustryin2010,P&TisnowaleadingShanghai-basedCROcompanyprovidingdrugdiscoveryanddevelopmentservicesworldwide.Withourtechnicalexpertiseandexcellentresearchfacilities,weofferbroadandintegratedchemicalsynthesis(customsynthesis,librarydesignandsynthesis),medicinalchemistry(hitgeneration,leadoptimization,andpreclinicaldevelopment),biological(earlyh...

    Shanghai Hope Chem Co., Ltd.

    Audited Supplier

    Country/Region:China

    Business Type: Manufacturer

    Contact Supplier SkypeSkype

  • D-Cycloserine

    Updatetime:Sep 21 2016

    FOB Price:1 USD/Gram Purity:99.9% Min. Order:10/Gram Supply Ability:10 Month/Metric Ton

    DetailDesc: D-Cycloserine Synonyms: CYCLOSERINE;D-CYCLOSERINE;D-CYCLOSERINE, STREPTOMYCES ORCHIDACEUS;D-4-AMINO-3-ISOXAZOLIDINONE;(R)-(+)-CYCLOSERINE;(R)-4-AMINO-ISOXAZOLIDIN-3-ONE;(R)-4-AMINO-3-ISOXAZOLIDINONE;R(+)-4-AMINO-3-ISOXAZOLIDINONE CAS: 68-41-7 MF: C3H6N2O2 MW: 102.09 EINECS: 200-...

    Tel:86-27-68580270
    Address:28# Golden Avenue, Golden Industrial Zone, Zhengdian Street, Jiangxia District, Wuhan City, Hubei, P. R. China
    Hubei Yuancheng Saichuang Technology Co., Ltd

    Audited Supplier

    Country/Region:China

    Business Type: Manufacturer

    Contact Supplier SkypeSkype

<Pre12345..6Next > Go to page

References of 3-Isoxazolidinone,4-amino-, (4R)- cas 68-41-7

} Toxicity

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NY2975000
CHEMICAL NAME :
3-Isoxazolidinone, 4-amino-, D-
CAS REGISTRY NUMBER :
68-41-7
BEILSTEIN REFERENCE NO. :
0080798
LAST UPDATED :
199612
DATA ITEMS CITED :
20
MOLECULAR FORMULA :
C3-H6-N2-O2
MOLECULAR WEIGHT :
102.11
WISWESSER LINE NOTATION :
T5OMVTJ DZ -D

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Human
DOSE/DURATION :
560 mg/kg/4W-I
TOXIC EFFECTS :
Behavioral - wakefulness Behavioral - tremor
REFERENCE :
DICHAK Diseases of the Chest. (Chicago, IL) V.1-56, 1935-69. For publisher information, see CHETBF. Volume(issue)/page/year: 29,241,1956
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Human - woman
DOSE/DURATION :
60 mg/kg
TOXIC EFFECTS :
Behavioral - coma
REFERENCE :
BMJOAE British Medical Journal. (British Medical Assoc., BMA House, Tavistock Sq., London WC1H 9JR, UK) V.1- 1857- Volume(issue)/page/year: 1,907,1965
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Human - woman
DOSE/DURATION :
40 mg/kg/2D-I
TOXIC EFFECTS :
Behavioral - hallucinations, distorted perceptions
REFERENCE :
TUBEAS Tubercle. (Williams & Wilkins Co., 428 E. Preston Street, Baltimore, MD 21202) V.1- 1919- Volume(issue)/page/year: 38,297,1957
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Human - man
DOSE/DURATION :
64 mg/kg/4D-I
TOXIC EFFECTS :
Behavioral - sleep Behavioral - altered sleep time (including change in righting reflex) Behavioral - convulsions or effect on seizure threshold
REFERENCE :
ABANAE Antibiotics Annual. (New York, NY) 1953-60. For publisher information, see AMACCQ. Volume(issue)/page/year: 3,148,1955/1956
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
REFERENCE :
ANTCAO Antibiotics and Chemotherapy (Washington, DC). (Washington, DC) V.1-12, 1951-62. For publisher information, see CLMEA3. Volume(issue)/page/year: 6,360,1956
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>3 gm/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
REFERENCE :
ANTCAO Antibiotics and Chemotherapy (Washington, DC). (Washington, DC) V.1-12, 1951-62. For publisher information, see CLMEA3. Volume(issue)/page/year: 6,360,1956
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
5290 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - ataxia
REFERENCE :
ANTCAO Antibiotics and Chemotherapy (Washington, DC). (Washington, DC) V.1-12, 1951-62. For publisher information, see CLMEA3. Volume(issue)/page/year: 6,360,1956
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
180 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85FZAT "Index of Antibiotics from Actinomycetes," Umezawa, H. et al., eds., Tokyo, Univ. of Tokyo Press, 1967 Volume(issue)/page/year: -,238,1967
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1400 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
YKYUA6 Yakkyoku. Pharmacy. (Nanzando, 4-1-11, Yushima, Bunkyo-ku, Tokyo, Japan) V.1- 1950- Volume(issue)/page/year: 31,1085,1980
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
560 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
YKYUA6 Yakkyoku. Pharmacy. (Nanzando, 4-1-11, Yushima, Bunkyo-ku, Tokyo, Japan) V.1- 1950- Volume(issue)/page/year: 31,1085,1980
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Gastrointestinal - nausea or vomiting
REFERENCE :
ANTCAO Antibiotics and Chemotherapy (Washington, DC). (Washington, DC) V.1-12, 1951-62. For publisher information, see CLMEA3. Volume(issue)/page/year: 6,360,1956
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
2 gm/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - tremor Gastrointestinal - nausea or vomiting
REFERENCE :
ANTCAO Antibiotics and Chemotherapy (Washington, DC). (Washington, DC) V.1-12, 1951-62. For publisher information, see CLMEA3. Volume(issue)/page/year: 6,708,1956
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Primate - monkey
DOSE/DURATION :
4 gm/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - ataxia Gastrointestinal - nausea or vomiting
REFERENCE :
ANTCAO Antibiotics and Chemotherapy (Washington, DC). (Washington, DC) V.1-12, 1951-62. For publisher information, see CLMEA3. Volume(issue)/page/year: 6,708,1956
TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ANTCAO Antibiotics and Chemotherapy (Washington, DC). (Washington, DC) V.1-12, 1951-62. For publisher information, see CLMEA3. Volume(issue)/page/year: 6,382,1956
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ANTCAO Antibiotics and Chemotherapy (Washington, DC). (Washington, DC) V.1-12, 1951-62. For publisher information, see CLMEA3. Volume(issue)/page/year: 6,360,1956
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
>1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ANTCAO Antibiotics and Chemotherapy (Washington, DC). (Washington, DC) V.1-12, 1951-62. For publisher information, see CLMEA3. Volume(issue)/page/year: 6,360,1956 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
15 gm/kg/60D-I
TOXIC EFFECTS :
Blood - pigmented or nucleated red blood cells Blood - changes in erythrocyte (RBC) count Related to Chronic Data - death
REFERENCE :
ANTCAO Antibiotics and Chemotherapy (Washington, DC). (Washington, DC) V.1-12, 1951-62. For publisher information, see CLMEA3. Volume(issue)/page/year: 6,708,1956
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Primate - monkey
DOSE/DURATION :
45 gm/kg/90D-I
TOXIC EFFECTS :
Gastrointestinal - hypermotility, diarrhea Blood - changes in bone marrow (not otherwise specified) Related to Chronic Data - death
REFERENCE :
ANTCAO Antibiotics and Chemotherapy (Washington, DC). (Washington, DC) V.1-12, 1951-62. For publisher information, see CLMEA3. Volume(issue)/page/year: 6,708,1956 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X5527 No. of Facilities: 31 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 756 (estimated) No. of Female Employees: 559 (estimated)

Safety

Poison by intraperitoneal route. Moderately toxic by intravenous and subcutaneous routes. Mildly toxic by ingestion. Human systemic effects by ingestion and possibly other routes: wakefulness, sleep, altered sleep time, hallucinations, distorted perceptions, tremors, convulsions, and coma. An antibiotic used in the treatment of human pulmonary tuberculosis. When heated to decomposition it emits toxic fumes of NOx.