Benzene (cas 71-43-2) Molecular Structure

CAS No. 71-43-2 (Benzene )

Molecular Formula: C6H6Molecular Weight: 78.11

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    DetailDesc: Name:Benzene CAS:71-43-2 MF:C6H6 MW:78.11 Assay:99%min Chinese name: Benzene English name: Benzene CAS RN: 71-43-2 EINECS No.: 200-753-7 Molecular formula: C 6 H 6 Molecular weight: 78.1134 Properties: It is colorless transparent volatilized liquid, and hardly soluble in water and soluble in alcohol, aether, acetone and other organic sol...

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References of Benzene cas 71-43-2

} Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LCLo inhalation 170000mg/m3 (170000mg/m3) ? "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 1, Pg. 324, 1955.
dog LCLo inhalation 146000mg/m3 (146000mg/m3) ? "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 1, Pg. 324, 1955.
dog LDLo oral 2gm/kg (2000mg/kg) ? "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1313, 1935.
frog LDLo subcutaneous 1400mg/kg (1400mg/kg) ? "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1313, 1935.
guinea pig LD50 skin > 9400uL/kg (9.4mL/kg) ? Toxicology and Applied Pharmacology. Vol. 7, Pg. 559, 1965.
guinea pig LDLo intraperitoneal 527mg/kg (527mg/kg) ? "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 1, Pg. 42, 1955.
human LCLo inhalation 65mg/m3/5Y (65mg/m3) BLOOD: OTHER CHANGES Archiv fuer Geschwulstforschung. Vol. 44, Pg. 145, 1974.
human LCLo inhalation 2pph/5M (20000ppm) ? Tabulae Biologicae. Vol. 3, Pg. 231, 1933.
human TCLo inhalation 100ppm (100ppm) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"

GASTROINTESTINAL: NAUSEA OR VOMITING
Industrial Medicine. Vol. 17, Pg. 199, 1948.
mammal (species unspecified) LCLo inhalation 20000ppm/5M (20000ppm) ? Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 138, Pg. 65, 1928.
mammal (species unspecified) LD50 oral 5700mg/kg (5700mg/kg) ? Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 39(4), Pg. 86, 1974.
mammal (species unspecified) LDLo intraperitoneal 1500mg/kg (1500mg/kg) PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE)

BEHAVIORAL: IRRITABILITY

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
American Journal of Hygiene. Vol. 7, Pg. 276, 1927.
man LDLo oral 50mg/kg (50mg/kg) ? Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 22, Pg. 883, 1980.
man LDLo unreported 194mg/kg (194mg/kg) ? "Poisoning; Toxicology, Symptoms, Treatments," 2nd ed., Arena, J.M., Springfield, IL, C.C. Thomas, 1970Vol. 2, Pg. 73, 1970.
man TCLo inhalation 150ppm/1Y-I (150ppm) BLOOD: OTHER CHANGES Blut. Vol. 28, Pg. 293, 1974.
mouse LC50 inhalation 9980ppm (9980ppm) BEHAVIORAL: GENERAL ANESTHETIC

BEHAVIORAL: MUSCLE WEAKNESS

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Journal of Industrial Hygiene and Toxicology. Vol. 25, Pg. 366, 1943.
mouse LD50 intraperitoneal 340mg/kg (340mg/kg) ? Annals of the New York Academy of Sciences. Vol. 243, Pg. 104, 1975.
mouse LD50 oral 4700mg/kg (4700mg/kg) ? Hygiene and Sanitation Vol. 32(3), Pg. 349, 1967.
mouse LD50 skin 48mg/kg (48mg/kg) ? Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. Vol. 1, Pg. 5, 1974.
rabbit LCLo inhalation 45000ppm/30M (45000ppm) ? Journal of Industrial Hygiene and Toxicology. Vol. 26, Pg. 69, 1944.
rabbit LD50 skin > 9400uL/kg (9.4mL/kg) ? Toxicology and Applied Pharmacology. Vol. 7, Pg. 559, 1965.
rabbit LDLo intravenous 88mg/kg (88mg/kg) PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE

GASTROINTESTINAL: GASTRITIS

SENSE ORGANS AND SPECIAL SENSES: HEMORRHAGE: EYE
Journal of Toxicology and Environmental Health. Vol. (Suppl,
rat LC50 inhalation 10000ppm/7H (10000ppm) ? "Toxicology and Biochemistry of Aromatic Hydrocarbons," Gerarde, H., New York, Elsevier, 1960Vol. -, Pg. 113, 1960.
rat LD50 intraperitoneal 1100ug/kg (1.1mg/kg) ? Acta Physiologica Polonica. Vol. 12, Pg. 173, 1961.
rat LD50 oral 930mg/kg (930mg/kg) BEHAVIORAL: TREMOR

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Toxicology and Applied Pharmacology. Vol. 7, Pg. 767, 1965.

Safety

Hazard Codes:?FlammableF,ToxicT
Risk Statements: 45-46-11-36/38-48/23/24/25-65-39/23/24/25-23/24/25?
R45:May cause cancer.?
R46:May cause heritable genetic damage.?
R11:Highly flammable.?
R36/38:Irritating to eyes and skin.?
R39:Danger of very serious irreversible effects.??
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed.?
R65:Harmful: may cause lung damage if swallowed.?
R48:Danger of serious damage to health by prolonged exposure.
Safety Statements: 53-45-36/37?
S53:Avoid exposure - obtain special instructions before use.?
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)?
S36/37:Wear suitable protective clothing and gloves.
RIDADR: UN 1114 3/PG 2
WGK Germany: 3
RTECS: CY1400000