Propanimidamide,3-[[[2-[(aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]-N-(aminosulfonyl)- (cas 76824-35-6) Molecular Structure

CAS No. 76824-35-6 (Propanimidamide,3-[[[2-[(aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]-N-(aminosulfonyl)- )

Molecular Formula: C8H15N7O2S3Molecular Weight: 337.45

Related Products Information

Page:1/8 < >
Contact Supplier
  • Famotidine

    Updatetime:Feb 23 2018

    FOB Price:3 USD/Kilogram Purity:95%, 99% Min. Order:1/Kilogram Supply Ability:50 Year/Metric Ton

    DetailDesc: Name: Propanimidamide,3-[[[2-[(aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]-N-(aminosulfonyl)- Synonyms: Apo-Famotidine;Apogastine;Bestidine;Brolin;Cepal;Dibrit 40;Digervin;Dispromil;Dispronil;Durater;Ganor;Ganor mite;Gaster;Gastridin;Gastrion;Gastro;Gastrodomina;Gastropen;H...

    Tel:86-571-88938639
    Address:9/F Unit 2 ChangdiTorch Building, 259 #WenSan Road
    Hangzhou Dayangchem Co., Ltd.

    Diamond member Diamond member Audited Supplier

    Country/Region:China

    Business Type: Manufacturer

    Contact Supplier MSNMSN SkypeSkype

  • Propanimidamide,3-[[[2-[(aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]-N-(aminosulfonyl)-

    Updatetime:Feb 21 2018

    FOB Price:1 USD/Kilogram Purity:99%min Min. Order:1/Kilogram Supply Ability:1000 Month/Kilogram

    DetailDesc: Name: Propanimidamide,3-[[[2-[(aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]-N-(aminosulfonyl)- Synonyms: Apo-Famotidine;Apogastine;Bestidine;Brolin;Cepal;Dibrit 40;Digervin;Dispromil;Dispronil;Durater;Ganor;Ganor mite;Gaster;Gastridin;Gastrion;Gastro;Gastrodomina;Gastropen;H...

    Tel:86-188-74586545
    Address:East and West Lake District, Wuhan, China
    Hubei XinRunde Chemical Co., Ltd

    Diamond member Diamond member Audited Supplier

    Country/Region:China

    Business Type: Manufacturer

    Contact Supplier SkypeSkype

  • Famotidine

    Updatetime:Feb 15 2018

    FOB Price:1 USD/Gram Purity:99% Min. Order:1/Gram Supply Ability:1000 Day/Gram

    DetailDesc: Famotidine Synonyms: [amino-3-[[[2-[(diaminomethylene)amino]-4-thiazolyl]-methyl]thio]propylidene]s;3-(((2-((aminoiminomethyl)amino)-4-thiazolyl)methyl)thio)-n-(aminosulfonyl)p;3-(((2-((diaminomethylene)amino)-4-thiazolyl)methyl)thio)-n(sup2)-sulfamoylp;aminosulfonyl)-;dispronil...

    Tel:86-27-59721024
    Address:No. 139, hanyang Road, hubei city, Hubei Prov. China 434000
    Wuhan H.X.K Fine Chemicals Co.,LTD

    Diamond member Diamond member Audited Supplier

    Country/Region:China

    Business Type: Manufacturer

    Contact Supplier

  • Strong 99% Famotidine 76824-35-6

    Updatetime:Feb 12 2018

    FOB Price:1 USD/Gram Purity:99% Min. Order:10/Gram Supply Ability:3 Month/Metric Ton

    DetailDesc: English name: Famotidine Synonyms: [amino-3 - [[2 - [diaminomethylene] amino] -4-thiazolyl] -methyl] thio] propylidene] s; 3 - ((2 - ((aminoiminomethyl) amino) -4-thiazolyl ) Methyl) thio) -n- (aminosulfonyl) p; CAS Number: 76824-35-6 Molecular formula: C8H15N7O2S3 Molecular wei...

    Tel:86-25-52178272
    Address:Room 901 Tianqinwan Garden NO.1008 Ssangyong Avenu
    Nanjing Bangnuo Biotechnology Co., Ltd.

    Diamond member Diamond member Audited Supplier

    Country/Region:China

    Business Type: Manufacturer

    Contact Supplier SkypeSkype

  • Famotidine

    Updatetime:Feb 12 2018

    FOB Price:1 USD/Gram Purity:99%min Min. Order:1/Gram Supply Ability:1 Month/Metric Ton

    DetailDesc: Quick Details ProName: High purity Famotidine with best price CasNo: 76824-35-6 Molecular Formula: C8H15N7O2S3 Appearance: white or almost white crystalline powd... Application: Histamine H2-receptor antagonist. Anti... DeliveryTime: within in 5-7 working days after recei... Pac...

    Tel:86-312-18103315327
    Address:east huaxia road pudong shanghai china
    shijiazhuang guizheng trade co.,ltd

    Diamond member Diamond member Audited Supplier

    Country/Region:China

    Business Type: Trading Company

    Contact Supplier SkypeSkype

  • Good quality Famotidine CAS 76824-35-6

    Updatetime:Feb 11 2018

    FOB Price:1 USD/Gram Purity:99% Min. Order:10/Gram Supply Ability:5 Month/Metric Ton

    DetailDesc: Antiinflammatory Pharmaceuticals Famotidine CAS 76824-35-6 for Treatment of PUD and GERD Quick Details for Famotidine Famotidine Product Name: Famotidine Famotidine Synonyms: [amino-3-[[[2-[(diaminomethylene)amino]-4-thiazolyl]-methyl]thio]propylidene]s;3-(((2-((aminoiminomethyl...

    Tel:86-1732-7098554
    Address:shuanglong road,jiangning, nanjing,jiangsu
    Nanjing Bangnuo Biotechnology Co., Ltd

    Diamond member Diamond member Audited Supplier

    Country/Region:China

    Business Type: Manufacturer

    Contact Supplier SkypeSkype

  • Propanimidamide,3-[[[2-[(aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]-N-(aminosulfonyl)- (Related Reference)

    Updatetime:Feb 09 2018

    Purity:0.98 Min. Order:1/Kilogram Supply Ability:100 Quarter/Kilogram

    DetailDesc:Name: Propanimidamide,3-[[[2-[(aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]-N-(aminosulfonyl)- (Related Reference) Molecular Formula: C8H15N7O2S3 CAS Registry Number: 76824-35-6 Synonyms: Apo-Famotidine; Apogastine; Bestidine; Brolin; Cepal; Dibrit 40; Digervin; Dispromil; Di...

    Tel:86-21-33758180
    Address:No 350,Guoshoujing Road, Zhangjiang Hi-tech Park, Pudong, Shanghai, China
    Shanghai Do Chemical Co.,Ltd

    Diamond member Diamond member Audited Supplier

    Country/Region:China

    Business Type: Manufacturer

    Contact Supplier

  • Lomustine

    Updatetime:Feb 09 2018

    Purity:99%min Min. Order: Supply Ability:Stable stock 

    DetailDesc: Lomustine CAS:76824-35-6

    Tel:0086-27-59207850
    Address:A2705,Dong Yi Shi Qu,129# XinHua Road
    Wuhan Fortuna Chemical Co., Ltd.

    Diamond member Diamond member Audited Supplier

    Country/Region:China

    Business Type: Manufacturer

    Contact Supplier MSNMSN SkypeSkype

  • Famotidine

    Updatetime:Jan 03 2018

    Tel:86-25-83697070
    Address:Rm.902 Longyin Plaza, No. 217 Zhongshan Rd.(N) Nanjing 210009,China
    Nanjing Chemlin Chemical Co., Ltd.

    Diamond member Diamond member Audited Supplier

    Country/Region:China

    Business Type: Manufacturer

    Contact Supplier MSNMSN SkypeSkype

  • Famotidine

    Updatetime:Aug 04 2017

    Purity:99%

    DetailDesc:White or kind of white crystal powder

    Tel:86-311-66600578
    Address:C-2103 Wonder Business Square, 15 Yuhua West Rd.
    AOPHARM

    Diamond member Diamond member Audited Supplier

    Country/Region:China

    Business Type: Manufacturer

    Contact Supplier MSNMSN SkypeSkype

  • Propanimidamide,3-[[[2-[(aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]-N-(aminosulfonyl)-

    Updatetime:Jul 18 2017

    FOB Price:100 USD/Kilogram Purity:99% Min. Order:1/Kilogram Supply Ability:100 Month/Kilogram

    DetailDesc:APIs Pharmaceutical Adjuvant Biochemicals & Biotech products

    Tel:86-571-85829152
    Address:Room 606, Fuyi Center, #298 Quanfuqiao Road, Jiang
    Jinlan Pharm-Drugs Technology Co., Limited

    Diamond member Diamond member Audited Supplier

    Country/Region:China

    Business Type: Manufacturer

    Contact Supplier SkypeSkype

  • Famotidine

    Updatetime:Nov 13 2015

    DetailDesc:High quality with nice price! J&H chemical provides you with the best chemical compounds you are looking for!

    Tel:86-571-87396430
    Address:No.200 Zhenhua Rd.Xihu Industrial Park, Hangzhou 310030, China
    Hangzhou J&H Chemical Co., Ltd

    Diamond member Diamond member Audited Supplier

    Country/Region:China

    Business Type: Manufacturer

    Contact Supplier

  • Famotidine high quality lower price76824-35-6

    Updatetime:Jan 29 2018

    FOB Price:1 USD/Gram Purity:99.9% Min. Order:10/Gram Supply Ability:1000 Month/Metric Ton

    DetailDesc: Product Details Keywords Famotidine High quality Famotidine CAS No.:76824-35-6 Quick Details ProName: High quality Famotidine CasNo: 76824-35-6 Molecular Formula: C8H15N7O2S3 Appearance: White crystalline powder Application: active pharmaceutical ingredients and ... DeliveryTime...

    Tel:86-311-66719475
    Address:pingandajie
    TELELIN PHARM CHEMICAL CO.,LTD

    Diamond member Diamond member

    Country/Region:China

    Business Type: Manufacturer

    Contact Supplier SkypeSkype

  • Famotidine

    Updatetime:Jun 28 2017

    FOB Price:1 USD/Gram Purity:98% Min. Order:1/Gram Supply Ability:10 Month/Kilogram

    DetailDesc:We could receive custom synthesis according to your requirements from lab scale to commercial scale

    Tel:86-21-60542966
    Address:Lane 299 Bisheng Rd,Pudong District
    Hui Chem Company Limited

    Audited Supplier

    Country/Region:China

    Business Type: Manufacturer

    Contact Supplier SkypeSkype

  • Famotidine

    Updatetime:Jun 06 2017

    Purity:contact us for more details about Famotidine, CAS:76824-35-6

    DetailDesc:FINETECH INDUSTRY LIMITED is a LONDON based CRO company providing drug discovery & development services to worldwide clients. FINETECH INDUSTRY LIMITED supplies the Famotidine, CAS:76824-35-6 with the most competitive price and the best quality. We can offer efficient service and the best package.Welcome the enquiries & orders around the ...

    Tel:86-27-87465837
    Address:chukang Road, Wuhan, Hubei 430073,
    Finetech Industry limited.

    Audited Supplier

    Country/Region:China

    Business Type: Manufacturer

    Contact Supplier

  • Antiinflammatory Pharmaceuticals Famotidine CAS 76824-35-6 for Treatment of PUD and GERD

    Updatetime:Apr 21 2017

    FOB Price:1 USD/Gram Purity:99% Min. Order:10/Gram Supply Ability:1000 Month/Kilogram

    DetailDesc: Antiinflammatory Pharmaceuticals Famotidine CAS 76824-35-6 for Treatment of PUD and GERD Quick Details for Famotidine Product Name: Famotidine Synonyms: [amino-3-[[[2-[(diaminomethylene)amino]-4-thiazolyl]-methyl]thio]propylidene]s;3-(((2-((aminoiminomethyl)amino)-4-thiazolyl)me...

    Tel:86-27-50755982
    Address:28# Golden Avenue, Golden Industrial Zone, Zhengdian Street, Jiangxia District, Wuhan City, Hubei, P. R. China
    Hubei Yuancheng Saichuang Technology Co., Ltd

    Audited Supplier

    Country/Region:China

    Business Type: Manufacturer

    Contact Supplier SkypeSkype

  • Famotidine / Hot Sale with High Quality (CAS :76824-35-6)

    Updatetime:Sep 29 2016

    FOB Price:1 USD/Kilogram Purity:99% Min. Order:10/Kilogram Supply Ability:50000 Quarter/Kilogram

    DetailDesc: Product Name: Famotidine Synonyms: [amino-3-[[[2-[(diaminomethylene)amino]-4-thiazolyl]-methyl]thio]propylidene]s;3-(((2-((aminoiminomethyl)amino)-4-thiazolyl)methyl)thio)-n-(aminosulfonyl)p;3-(((2-((diaminomethylene)amino)-4-thiazolyl)methyl)thio)-n(sup2)-sulfamoylp;aminosulfon...

    Tel:86-27-59212929
    Address:daijiashan 45,jiangan economic departmen zone,wuhan,hubei,China
    Wuhan Dahua Weiye Pharmaceutical Co.,Ltd

    Audited Supplier

    Country/Region:China

    Business Type: Manufacturer

    Contact Supplier SkypeSkype

  • Propanimidamide,3-[[[2-[(aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]-N-(aminosulfonyl)-

    Updatetime:Jul 28 2016

    FOB Price:0 RMB/Kilogram Purity:99 Min. Order:1/Kilogram Supply Ability:1000 Year/Metric Ton

    DetailDesc: Product Name: Famotidine Synonyms: [amino-3-[[[2-[(diaminomethylene)amino]-4-thiazolyl]-methyl]thio]propylidene]s;3-(((2-((aminoiminomethyl)amino)-4-thiazolyl)methyl)thio)-n-(aminosulfonyl)p;3-(((2-((diaminomethylene)amino)-4-thiazolyl)methyl)thio)-n(sup2)-sulfamoylp;aminosulfon...

    Tel:0086-531-58773055
    Address:No.59 Gongye South RD
    Jinan Haohua Industry Co., Ltd.

    Audited Supplier

    Country/Region:China

    Business Type: Manufacturer

    Contact Supplier SkypeSkype

  • Famotidine 76824-35-6

    Updatetime:Dec 10 2015

    Min. Order:1/Gram Supply Ability:10 Month/Metric Ton

    DetailDesc:Famotidine 76824-35-6

    Tel:86-571-85232161
    Address:6th Floor, Block C, 7th Building, Xigang Xinjie, Xihu Industrial Park, Sandun Town, Hangzhou, China
    AFINE CHEMICALS LIMITED

    Audited Supplier

    Country/Region:China

    Business Type: Manufacturer

    Contact Supplier SkypeSkype

  • Famotidine

    Updatetime:May 25 2015

    DetailDesc:Shijiazhuang Sdyano Fine Chemical Co., Ltd

    Tel:86-311-80800737
    Address:Room 37-2-2501, Yiyuan Dong Gang Jianshe Nan Stree
    Shijiazhuang Sdyano Fine Chemical Co., Ltd

    Audited Supplier

    Country/Region:China

    Business Type: Manufacturer

    Contact Supplier MSNMSN SkypeSkype

<Pre12345..8Next > Go to page

References of Propanimidamide,3-[[[2-[(aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]-N-(aminosulfonyl)- cas 76824-35-6

} Toxicity

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UA2300000
CHEMICAL NAME :
Propanimidamide, 3-(((2-((aminoiminomethyl)amino)-4-thiazolyl)methyl)t hio)-N- (aminosulfonyl)-
CAS REGISTRY NUMBER :
76824-35-6
LAST UPDATED :
199709
DATA ITEMS CITED :
18
MOLECULAR FORMULA :
C8-H15-N7-O2-S3
MOLECULAR WEIGHT :
337.48

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Human - man
DOSE/DURATION :
4 mg/kg/7D-I
TOXIC EFFECTS :
Liver - jaundice (or hyperbilirubinemia) hepatocellular
REFERENCE :
APHRER Annals of Pharmacotherpy. (Harvey Whitney Books Co., POB 42696, Cincinnati, OH 45242) V. 26- 1992- Volume(issue)/page/year: 28,40,1994
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
4049 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970- Volume(issue)/page/year: 19,544,1988
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
800 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
DIGEBW Digestion. (S. Karger Pub., Inc., 79 Fifth Ave., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 32(Suppl 1),7,1985
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
800 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
DIGEBW Digestion. (S. Karger Pub., Inc., 79 Fifth Ave., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 32(Suppl 1),7,1985
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
204 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 18,6125,1984
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
4686 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970- Volume(issue)/page/year: 16,590,1985
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
778 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 26,147,1983
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
800 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
DIGEBW Digestion. (S. Karger Pub., Inc., 79 Fifth Ave., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 32(Suppl 1),7,1985
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
254 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970- Volume(issue)/page/year: 16,590,1985 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
18200 mg/kg/13W-I
TOXIC EFFECTS :
Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Skin and Appendages - dermatitis, other (after systemic exposure) Related to Chronic Data - death
REFERENCE :
DIGEBW Digestion. (S. Karger Pub., Inc., 79 Fifth Ave., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 32(Suppl 1),7,1985 ** REPRODUCTIVE DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
2800 mg/kg
SEX/DURATION :
female 15-22 day(s) after conception lactating female 21 day(s) post-birth
TOXIC EFFECTS :
Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain)
REFERENCE :
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 26,543,1983
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
22 gm/kg
SEX/DURATION :
female 7-17 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetal death Reproductive - Effects on Newborn - physical
REFERENCE :
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 26,489,1983
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
5500 mg/kg
SEX/DURATION :
female 7-17 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
REFERENCE :
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 26,489,1983
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
1100 mg/kg
SEX/DURATION :
multigenerations
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetal death
REFERENCE :
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 26,489,1983
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
248 gm/kg
SEX/DURATION :
male 12 week(s) pre-mating female 2 week(s) pre-mating - 4 day(s) post-birth
TOXIC EFFECTS :
Reproductive - Effects on Newborn - viability index (e.g., # alive at day 4 per # born alive)
REFERENCE :
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 26,551,1983
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intravenous
DOSE :
2200 mg/kg
SEX/DURATION :
female 7-17 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain)
REFERENCE :
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 26,831,1983
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
6500 mg/kg
SEX/DURATION :
female 6-18 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 26,565,1983
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intravenous
DOSE :
130 mg/kg
SEX/DURATION :
female 6-18 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)
REFERENCE :
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 26,573,1983

Safety

Moderately toxic by intraperitoneal, subcutaneous, and intravenous routes. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx and SOx.