8-Azoniabicyclo[3.2.1]octane,3-[(2-hydroxy-2-phenylacetyl)oxy]-8,8-dimethyl-, bromide (1:1), (3-endo)- (cas 80-49-9) Molecular Structure

CAS No. 80-49-9 (8-Azoniabicyclo[3.2.1]octane,3-[(2-hydroxy-2-phenylacetyl)oxy]-8,8-dimethyl-, bromide (1:1), (3-endo)- )

Molecular Formula: C17H24NO3.BrMolecular Weight: 370.28

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References of 8-Azoniabicyclo[3.2.1]octane,3-[(2-hydroxy-2-phenylacetyl)oxy]-8,8-dimethyl-, bromide (1:1), (3-endo)- cas 80-49-9

} Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LD50 intraperitoneal 120mg/kg (120mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 105, Pg. 166, 1952.
guinea pig LD50 oral 1gm/kg (1000mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 105, Pg. 166, 1952.
guinea pig LD50 subcutaneous 75mg/kg (75mg/kg)   Archives Internationales de Pharmacodynamie et de Therapie. Vol. 137, Pg. 375, 1962.
mouse LD50 intraperitoneal 60mg/kg (60mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 105, Pg. 166, 1952.
mouse LD50 oral 1400mg/kg (1400mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 105, Pg. 166, 1952.
mouse LD50 subcutaneous 130mg/kg (130mg/kg)   French Demande Patent Document. Vol. #2035763,
rat LD50 intraperitoneal 82mg/kg (82mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 105, Pg. 166, 1952.
rat LD50 intravenous 12mg/kg (12mg/kg)   Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 236, Pg. 149, 1959.
rat LD50 oral 1200mg/kg (1200mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 105, Pg. 166, 1952.
rat LD50 subcutaneous 800mg/kg (800mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 105, Pg. 166, 1952.

Safety

Poison by intraperitoneal and subcutaneous routes. Moderately toxic by ingestion. An anticholinergic agent. An FDA over-the-counter and proprietary drug. When heated to decomposition it emits very toxic fumes of Br and NOx.

Risk Statements:  20/21/22
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.
Safety Statements:  22-26-36 
S22:Do not breathe dust. 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36:Wear suitable protective clothing.
RIDADR:  1544
RTECS:  MS9000000