Ganciclovir (cas 82410-32-0) Molecular Structure

CAS No. 82410-32-0 (Ganciclovir )

Molecular Formula: C9H13N5O4Molecular Weight: 255.23062

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References of Ganciclovir cas 82410-32-0

} Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 intravenous > 150mg/kg (150mg/kg) ? Drugs in Japan Vol. -, Pg. 291, 1990.
dog LD50 oral > 1gm/kg (1000mg/kg) ? Drugs in Japan Vol. -, Pg. 291, 1990.
mouse LD50 intraperitoneal 1gm/kg (1000mg/kg) ? Journal of Medicinal Chemistry. Vol. 26, Pg. 759, 1983.
mouse LD50 intravenous 900mg/kg (900mg/kg) ? Drugs in Japan Vol. -, Pg. 291, 1990.
mouse LD50 oral > 2gm/kg (2000mg/kg) ? Drugs in Japan Vol. -, Pg. 291, 1990.

Safety

Common adverse drug reactions >=1% of patients) include: neutropenia, granulocytopenia, thrombocytopenia, fever, nausea, vomiting, dyspepsia, diarrhoea, abdominal pain, flatulence, anorexia, raised liver enzymes, headache, confusion, hallucination, anaemia, pain and phlebitis at injection site (due to high pH), sweating, rash.
Hazard Codes:?ToxicT
Risk Statements: 46-60-61?
R46:May cause heritable genetic damage.?
R60:May impair fertility.?
R61:May cause harm to the unborn child.
Safety Statements: 53-36/37/39-45?
S53:Avoid exposure - obtain special instructions before use.?
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.?
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
WGK Germany: 3
RTECS of Ganciclovir (CAS NO.82410-32-0): MF8407000