Itraconazole (cas 84625-61-6) Molecular Structure

CAS No. 84625-61-6 (Itraconazole )

Molecular Formula: C35H38Cl2N8O4Molecular Weight: 705.63342

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    DetailDesc: English name: Itraconazole Benzoyl) phenyl) -2,4-dihyd; 3h-1, 3-dioxolan-4-yl) methoxy) phenyl) -1-piperazinyl , 4-triazol-3-one, 4- (4- (4- (4- (2,4-dichlorophenyl) -2- (1h-1,2,4-triazol; ro- 1-methylpropyl) -; ITRACONAZOLE-D3 CAS Number: 84625-61-6 Molecular formula: C35H38Cl2...

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    DetailDesc: CAS: 84625-61-6 Precise quality: 704.23900 Molecular formula: C35H38Cl2N8O4 logP: 5.70730 Molecular weight: 705.63300 PSA: 104.70000 Enquiries to check the supplier immediately Using WeChat scan, pay attention to the encyclopedia The basic information Chinese name: itraconazole ...

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    DetailDesc:Name: Itraconazole (Related Reference) Molecular Formula: C35H38Cl2N8O4 CAS Registry Number: 84625-61-6 Synonyms: ITCZ; ITR; 3H-1,2,4-Triazol-3-one, 4-[4-[4-[4-[[2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-pipera-zinyl]phenyl]-2,4-di...

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    DetailDesc: Product Description Description Itraconazole is a triazole antifungal agent. It inhibits the fungal CYP(cytochrome P450) oxidase-mediated synthesis of ergosterol. Itraconazole also acts as an effective hedgehog signaling inhibitor in a Ptch-independent manner, presumably by bind...

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    DetailDesc: itraconazole CAS: 84625-61-6 MF: C35H38Cl2N8O4 MW: 705.63 mp 166°C storage temp. 2-8°C solubility chloroform: 50 mg/mL, clear, colorless Stability: Stable. Incompatible with strong oxidizing agents. Chemical Properties Off-White Crystalline Solid Usage An orally active antimycotic structurally related to Ketoconazole. Antifungal Purity: 98.5% Usage: API Package: 1KG foil bag; 25Kg drum

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    DetailDesc: Name: Itraconazole Synonyms: ITCZ;ITR;3H-1,2,4-Triazol-3-one, 4-[4-[4-[4-[[2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-pipera-zinyl]phenyl]-2,4-dihydro-2-(1-methylpropyl);ITZ;Itraconazolum [Latin];R 51211;Itrizole;Itraconazole [USAN:BAN:INN:JAN];Itraconazole (JAN/USAN);Itrizole (TN);Itraconazol [Spanish];3H-1,2,4-Triazol-3-one, 4-(4-(4-(4-((2-(2,4-di...

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References of Itraconazole cas 84625-61-6

} Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 oral > 200mg/kg (200mg/kg) ? Reviews of Infectious Diseases. Vol. 9(Suppl,
guinea pig LD50 oral > 160mg/kg (160mg/kg) ? Reviews of Infectious Diseases. Vol. 9(Suppl,
man TDLo oral 240mg/kg/6W-I (240mg/kg) LIVER: "JAUNDICE, OTHER OR UNCLASSIFIED"

LIVER: LIVER FUNCTION TESTS IMPAIRED
Lancet. Vol. 340, Pg. 251, 1992.
mouse LD50 intravenous 46400ug/kg (46.4mg/kg) ? Kiso to Rinsho. Clinical Report. Vol. 25, Pg. 381, 1991.
mouse LD50 oral > 320mg/kg (320mg/kg) ? Reviews of Infectious Diseases. Vol. 9(Suppl,
rat LD50 intravenous 40mg/kg (40mg/kg) ? Kiso to Rinsho. Clinical Report. Vol. 25, Pg. 381, 1991.
rat LD50 oral > 320mg/kg (320mg/kg) ? Reviews of Infectious Diseases. Vol. 9(Suppl,
women TDLo oral 32mg/kg/8D-I (32mg/kg) SKIN AND APPENDAGES (SKIN): HAIR: OTHER British Medical Journal. Vol. 293, Pg. 822, 1986.
women TDLo oral 140mg/kg/5W-I (140mg/kg) LIVER: "JAUNDICE, OTHER OR UNCLASSIFIED"

LIVER: LIVER FUNCTION TESTS IMPAIRED

SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"
Lancet. Vol. 340, Pg. 251, 1992.

Safety

Hazard Codes:?IrritantXi,HarmfulXn
Risk Statements: 36/37/38-36/38-22?
R36/37/38: Irritating to eyes, respiratory system and skin.?
R36/38: Irritating to eyes and skin.?
R22: Harmful if swallowed.
Safety Statements: 22-26-36?
S22: Do not breathe dust.?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S36: Wear suitable protective clothing.
WGK Germany: 3
RTECS Itraconazole (CAS NO.84625-61-6): XZ5481000