Glimepiride (cas 93479-97-1) Molecular Structure

CAS No. 93479-97-1 (Glimepiride )

Molecular Formula: C24H34N4O5SMolecular Weight: 490.62

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    DetailDesc:Name: Glimepiride (Related Reference) Molecular Formula: C24H34N4O5S CAS Registry Number: 93479-97-1 Synonyms: 1h-pyrrole-1-carboxamide,2,5-dihydro-3-ethyl-4-methyl-n-(2-(4-(((((4-methylcyc; glimepirid; hoe490; trans-lohexyl)amino)carbonyl)amino)sulfonyl)phenyl)ethyl)-2-oxo; 1-[[...

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    DetailDesc:CAS: 93479-97-1 M.F.:C24H34N4O5S M.W.:490.6156

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References of Glimepiride cas 93479-97-1

} Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
man TDLo oral 28ug/kg/2D-I (0.028mg/kg) BLOOD: HEMORRHAGE
BLOOD: THROMBOCYTOPENIA
SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"
Annals of Pharmacotherpy. Vol. 34, Pg. 120, 2000.
mouse LD50 unreported > 10gm/kg (10000mg/kg) ? Diabetes Frontier. Vol. 3, Pg. 565, 1992.
rat LD intraperitoneal > 3950mg/kg (3950mg/kg) LIVER: OTHER CHANGES Arzneimittel-Forschung. Drug Research. Vol. 43, Pg. 547, 1993.
rat LD oral > 10gm/kg (10000mg/kg) LIVER: OTHER CHANGES Arzneimittel-Forschung. Drug Research. Vol. 43, Pg. 547, 1993.
rat LD50 unreported > 10gm/kg (10000mg/kg) ? Diabetes Frontier. Vol. 3, Pg. 565, 1992.

Safety

Hazard Codes:?HarmfulXn,IrritantXi
Risk Statements: 21-36/38-46-62-63?
R21:Harmful in contact with skin.?
R36/38:Irritating to eyes and skin.?
R46:May cause heritable genetic damage.?
R62:Risk of impaired fertility.?
R63:Possible risk of harm to the unborn child.
Safety Statements: 25-26-36/37-53
S25:Avoid contact with eyes.?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S36/37:Wear suitable protective clothing and gloves.?
S53:Avoid exposure - obtain special instructions before use.
WGK Germany: 3
RTECS: UX9363950