Asbestos (cas 1332-21-4) MSDS

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MSDS   :
  Asbestos
 
  
 CAS   
:
  1332-21-4 
 SYNONYMS   
:
  * Amianthus
 
 * Amosite (Obs.)
 
 * Amphibole
 
 * Asbest
 
 * Asbestos
 
 * Asbestos fiber
 
 * Asbestos fibre
 
 * Fibrous grunerite
 
 * NCI C08991
 
 
 
  
Catalog of Chemical Suppliers, Buyers, Custom Synthesis Companies And Equipment Manufacturers
[ Asbestos 1332-21-4 ]
  
                      *** CHEMICAL IDENTIFICATION ***
 
 
 
 RTECS NUMBER            : CI6475000
 
 CHEMICAL NAME           : Asbestos
 
 CAS REGISTRY NUMBER     : 1332-21-4
 
 LAST UPDATED            : 199712
 
 DATA ITEMS CITED        : 41
 
 COMPOUND DESCRIPTOR     : Tumorigen
 
                           Mutagen
 
                           Human
 
                           Natural Product
 
 SYNONYMS/TRADE NAMES :
 
    * Amianthus
 
    * Amosite (Obs.)
 
    * Amphibole
 
    * Asbest
 
    * Asbestos
 
    * Asbestos fiber
 
    * Asbestos fibre
 
    * Fibrous grunerite
 
    * NCI C08991
 
  
 
                        *** HEALTH HAZARD DATA ***
 
  
 
                         ** ACUTE TOXICITY DATA **
 
  
 
 TYPE OF TEST            : TCLo - Lowest published toxic concentration
 
 ROUTE OF EXPOSURE       : Inhalation
 
 SPECIES OBSERVED        : Human
 
 DOSE/DURATION           : 1.2 fb/cc/19Y-C
 
 TOXIC EFFECTS :
 
    Lungs, Thorax, or Respiration - pleural effusion
 
    Lungs, Thorax, or Respiration - dyspnea
 
    Lungs, Thorax, or Respiration - sputum
 
 REFERENCE :
 
    ARDSBL American Review of Respiratory Disease.  (American Lung Assoc., 1740
 
    Broadway, New York, NY 10019)  V.80-   1959-  Volume(issue)/page/year:
 
    104,576,1971
 
  
 
                           ** TUMORIGENIC DATA **
 
  
 
 TYPE OF TEST            : TDLo - Lowest published toxic dose
 
 ROUTE OF EXPOSURE       : Implant
 
 SPECIES OBSERVED        : Rodent - rat
 
 DOSE/DURATION           : 750 mg/kg
 
 TOXIC EFFECTS :
 
    Tumorigenic - equivocal tumorigenic agent by RTECS criteria
 
    Tumorigenic - tumors at site of application
 
 REFERENCE :
 
    ZEKBAI Zeitschrift fuer Krebsforschung.  (Berlin, Fed. Rep. Ger.)  V.1-75,
 
    1903-71.  For publisher information, see JCROD7.  Volume(issue)/page/year:
 
    62,561,1958
 
  
 
 TYPE OF TEST            : TDLo - Lowest published toxic dose
 
 ROUTE OF EXPOSURE       : Intraperitoneal
 
 SPECIES OBSERVED        : Rodent - mouse
 
 DOSE/DURATION           : 80 mg/kg
 
 TOXIC EFFECTS :
 
    Tumorigenic - equivocal tumorigenic agent by RTECS criteria
 
    Tumorigenic - tumors at site of application
 
 REFERENCE :
 
    PAACA3 Proceedings of the American Association for Cancer Research. (Waverly
 
    Press, 428 E. Preston St., Baltimore, MD 21202)  V.1-    1954-
 
    Volume(issue)/page/year: 24,61,1983
 
  
 
                             ** MUTATION DATA **
 
  
 
 TYPE OF TEST            : Mutation in microorganisms
 
 TEST SYSTEM             : Bacteria - Escherichia coli
 
 DOSE/DURATION           : 10 mg/plate
 
 REFERENCE :
 
    PSEBAA Proceedings of the Society for Experimental Biology and Medicine.
 
    (Academic Press, Inc., 1 E. First St., Duluth, MN 55802)  V.1-    1903/04-
 
    Volume(issue)/page/year: 177,343,1984
 
 
 
                               *** REVIEWS ***
 
  
 
    ACGIH TLV-Confirmed human carcinogen
 
    DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
 
    (BEIs) booklet issues by American Conference of Governmental Industrial
 
    Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year:
 
    TLV/BEI,1997
 
 
 
    ACGIH TLV-STEL 2 fibers/cc, longer than 5 um
 
    DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
 
    (BEIs) booklet issues by American Conference of Governmental Industrial
 
    Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year:
 
    TLV/BEI,1997
 
 
 
    IARC Cancer Review:Human Sufficient Evidence
 
    IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
 
    to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
 
    V.1-    1972-  Volume(issue)/page/year: 2,17,1973
 
 
 
    IARC Cancer Review:Animal Sufficient Evidence
 
    IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
 
    to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
 
    V.1-    1972-  Volume(issue)/page/year: 2,17,1973
 
 
 
    IARC Cancer Review:Human Sufficient Evidence
 
    IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
 
    to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
 
    V.1-    1972-  Volume(issue)/page/year: 14,11,1977
 
 
 
    IARC Cancer Review:Animal Sufficient Evidence
 
    IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
 
    to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
 
    V.1-    1972-  Volume(issue)/page/year: 14,11,1977
 
 
 
    IARC Cancer Review:Group 1
 
    IMSUDL IARC Monographs, Supplement.  (WHO Publications Centre USA, 49
 
    Sheridan Ave., Albany, NY 12210)  No.1-    1979-  Volume(issue)/page/year:
 
    7,106,1987
 
 
 
    TOXICOLOGY REVIEW
 
    JPMSAE Journal of Pharmaceutical Sciences.  (American Pharmaceutical Assoc.,
 
    2215 Constitution Ave., NW, Washington, DC 20037)  V.50-    1961-
 
    Volume(issue)/page/year: 64,1435,1975
 
 
 
    TOXICOLOGY REVIEW
 
    PEDIAU Pediatrics.  (American Academy of Pediatrics, P.O. Box 1034,
 
    Evanston, IL 60204) V.1-    1948-  Volume(issue)/page/year: 57,462,1976
 
 
 
    TOXICOLOGY REVIEW
 
    JJOMDZ JOM, Journal of Occupational Medicine.  (American Occupational
 
    Medicine Assoc., 150 N. Wacker Dr., Chicago, IL 60606)  V.10-    1968-
 
    Volume(issue)/page/year: 15,808,1973
 
 
 
    TOXICOLOGY REVIEW
 
    CANCAR Cancer (Philadelphia).  (Lippincott/Harper, Journal Fulfillment
 
    Dept., 2350 Virginia Ave., Hagerstown, MD 21740)  V.1-    1948-
 
    Volume(issue)/page/year: 39,1792,1977
 
 
 
    TOXICOLOGY REVIEW
 
    85CVA2 "Oncology 1970, Proceedings of the Tenth International Cancer
 
    Congress," Chicago, Year Book Medical Pub., 1971  Volume(issue)/page/year:
 
    5,55,1970
 
 
 
    TOXICOLOGY REVIEW
 
    31BYAP "Experimental Lung Cancer:  Carcinogenesis and Bioassays,
 
    International Symposium, 1974," Karbe, E., and J.F. Park, eds.,
 
    Springer-Verlag New York, Inc., 1974  Volume(issue)/page/year: -,92,1974
 
 
 
    TOXICOLOGY REVIEW
 
    ZHPMAT Zentralblatt fuer Bakteriologie, Parasitenkunde,
 
    Infektionskrankheiten und Hygiene, Abteilung 1: Originale, Reihe B: Hygiene,
 
    Krankenhaushygiene, Betriebshygiene, Praeventive Medizin. (Stuttgart, Fed.
 
    Rep. Ger.)  V.155-169, 1971-1979.  For publisher information, see ZAOMDC. 
 
    Volume(issue)/page/year: 166,113,1978
 
 
 
    TOXICOLOGY REVIEW
 
    NOSYBW Nobel Symposium.  (Nobel Foundation, Sturegatan 14, S-11436
 
    Stockholm, Sweden)  No.1-    1966-  Volume(issue)/page/year: 40,311,1977
 
 
 
    TOXICOLOGY REVIEW
 
    PEXTAR Progress in Experimental Tumor Research.  (S. Karger AG, Postfach
 
    CH-4009 Basel, Switzerland) V.1-    1960-  Volume(issue)/page/year:
 
    12,102,1969
 
 
 
    TOXICOLOGY REVIEW
 
    NTIS** National Technical Information Service.  (Springfield, VA 22161)
 
    Formerly U.S. Clearinghouse for Scientific & Technical Information.
 
    Volume(issue)/page/year: CONF-691001
 
 
 
    TOXICOLOGY REVIEW
 
    CNDIBJ Cahiers de Notes Documentaires.  (Institut National de Recherche et
 
    de Securite, 30 rue Olivier Noyer, 75680 Paris Cedex, 14, France)  No.1-
 
    1955-  Volume(issue)/page/year: 85,559,1976
 
 
 
                     *** U.S. STANDARDS AND REGULATIONS ***
 
  
 
    MSHA STANDARD-air:TWA 5 fb/cc (fb > 5 um)
 
    DTLWS* "Documentation of the Threshold Limit Values for Substances in
 
    Workroom Air," Supplements. For publisher information, see 85INA8.
 
    Volume(issue)/page/year: 3,33,1973
 
 
 
    OSHA PEL (Construc):see CFR 29,1926.58
 
    CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
 
    of Documents, Washington, DC 20402)  Volume(issue)/page/year:
 
    29,1926.55,1994
 
 
 
    OSHA PEL (Shipyard):8H TWA 0.2 f/cc
 
    CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
 
    of Documents, Washington, DC 20402)  Volume(issue)/page/year:
 
    29,1915.1000,1993
 
 
 
    OSHA-CANCER AND LUNG DISEASE HAZARD
 
    CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
 
    of Documents, Washington, DC 20402)  Volume(issue)/page/year:
 
    29,1910.1001,1991
 
 
 
                     *** OCCUPATIONAL EXPOSURE LIMITS ***
 
  
 
    OEL-FRANCE:TWA 1 fiber/ml JAN 1993
 
    
 
    OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV
 
    
 
    OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV
 
 
 
          *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
 
 
 
 NIOSH RECOMMENDED EXPOSURE LEVEL (REL) :
 
    NIOSH REL TO ASBESTOS-air:100M TWA 0.1 fb/cc in a 400L air sample
 
 REFERENCE :
 
    NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of
 
    Health, Education, and Welfare, Reports and Memoranda.
 
    Volume(issue)/page/year: DHHS #92-100,1992
 
 
 
 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
 
    NOHS - National Occupational Hazard Survey (1974)
 
      NOHS Hazard Code - 90310
 
        No. of Facilities: 30863 (estimated)
 
        No. of Industries: 154
 
        No. of Occupations: 117
 
        No. of Employees: 449904 (estimated)
 
    
 
    NOES - National Occupational Exposure Survey (1983)
 
      NOES Hazard Code - 90310
 
        No. of Facilities: 15617 (estimated)
 
        No. of Industries: 81
 
        No. of Occupations: 86
 
        No. of Employees: 215265 (estimated)
 
        No. of Female Employees: 9727 (estimated)
 
 
 
                           *** STATUS IN U.S. ***
 
  
 
    EPA GENETOX PROGRAM 1988, Positive: Carcinogenicity-mouse/rat
 
    
 
    EPA GENETOX PROGRAM 1988, Negative: TRP reversion
 
    
 
    EPA TSCA Section 8(b) CHEMICAL INVENTORY
 
    
 
    EPA TSCA Section 8(d) unpublished health/safety studies
 
    
 
    On EPA IRIS database
 
    
 
    EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998
 
    
 
    NIOSH CURRENT INTELLIGENCE BULLETIN 5, 1975
 
    
 
    NIOSH Analytical Method, 1994: Asbestos (bulk) by PLM, 9002; by PCM, 7400;
 
    by TEM, 7402
 
    
 
    NTP 7th Annual Report on Carcinogens, 1992 : known to be carcinogenic
 
 
 
  
 
                             *** END OF RECORD ***