Tridymite (SiO2) (9CI) (cas 15468-32-3) MSDS

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MSDS   :
 Silica, crystalline - tridymite
CAS  
:
 15468-32-3
SYNONYMS  
:
 * Christensenite
* Silica, crystalline-tridymite
* Tridimite
* Tridymite
* alpha-Tridymite
* Tridymite 118

Catalog of Chemical Suppliers, Buyers, Custom Synthesis Companies And Equipment Manufacturers
[ Silica, crystalline - tridymite 15468-32-3 ]
                     *** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : VV7335000
CHEMICAL NAME           : Silica, crystalline - tridymite
CAS REGISTRY NUMBER     : 15468-32-3
OTHER CAS REGISTRY NOS. : 1317-94-8
                          12414-70-9
LAST UPDATED            : 199712
DATA ITEMS CITED        : 31
MOLECULAR FORMULA       : O2-Si
MOLECULAR WEIGHT        : 60.09
WISWESSER LINE NOTATION :  SI  O2
COMPOUND DESCRIPTOR     : Tumorigen
                          Mutagen
                          Human
SYNONYMS/TRADE NAMES :
   * Christensenite
   * Silica, crystalline-tridymite
   * Tridimite
   * Tridymite
   * alpha-Tridymite
   * Tridymite 118
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Human
DOSE/DURATION           : 16 mppcf/8H/17.9Y-I
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - fibrosis, focal (pneumoconiosis)
   Lungs, Thorax, or Respiration - cough
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: PB246-697
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intratracheal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - fibrosis, focal (pneumoconiosis)
REFERENCE :
   BJIMAG British Journal of Industrial Medicine.  (British Medical Journal,
   Box 560B, Kennebunkport, ME 04046)  V.1-    1944-  Volume(issue)/page/year:
   10,9,1953
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intrapleural
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Blood - lymphoma, including Hodgkin's disease
REFERENCE :
   BJCAAI British Journal of Cancer.  (Macmillan Press Ltd., Houndmills,
   Basingstoke, Hants. RG21 2XS, UK)  V.1-    1947-  Volume(issue)/page/year:
   41,908,1980
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intratracheal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 400 mg/kg
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
REFERENCE :
   PAACA3 Proceedings of the American Association for Cancer Research. (Waverly
   Press, 428 E. Preston St., Baltimore, MD 21202)  V.1-    1954-
   Volume(issue)/page/year: 15,6,1974
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Human Lymphocyte
DOSE/DURATION           : 13514 ug/kg
REFERENCE :
   BJIMAG British Journal of Industrial Medicine.  (British Medical Journal,
   Box 560B, Kennebunkport, ME 04046)  V.1-    1944-  Volume(issue)/page/year:
   47,110,1990

                              *** REVIEWS ***
 
   ACGIH TLV-TWA 0.05 mg/m3, respirable dust
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year:
   TLV/BEI,1997

   IARC Cancer Review:Animal Sufficient Evidence
   IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
   to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
   V.1-    1972-  Volume(issue)/page/year: 42,39,1987

   IARC Cancer Review:Human Limited Evidence
   IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
   to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
   V.1-    1972-  Volume(issue)/page/year: 42,39,1987

   IARC Cancer Review:Animal Limited Evidence
   IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
   to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
   V.1-    1972-  Volume(issue)/page/year: 68,41,1997

   IARC Cancer Review:Group 2A
   IMSUDL IARC Monographs, Supplement.  (WHO Publications Centre USA, 49
   Sheridan Ave., Albany, NY 12210)  No.1-    1979-  Volume(issue)/page/year:
   7,341,1987

                    *** U.S. STANDARDS AND REGULATIONS ***
 
   MSHA STANDARD-respirable dust in air:TWA 10 mg/m3/2(% resp. SiO2+2)
   DTLWS* "Documentation of the Threshold Limit Values for Substances in
   Workroom Air," Supplements. For publisher information, see 85INA8.
   Volume(issue)/page/year: 3,33,1973

   MSHA STANDARD-total dust in air:TWA 30 mg/m3/2(% resp. SiO2+3)
   DTLWS* "Documentation of the Threshold Limit Values for Substances in
   Workroom Air," Supplements. For publisher information, see 85INA8.
   Volume(issue)/page/year: 3,33,1973

   OSHA PEL (Gen Indu):8H TWA 5 mg/m3/(% resp SiO2+2)
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1910.1000,1994

   OSHA PEL (Construc):8H TWA 5 mg/m3/(% resp SiO2+2)
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1926.55,1994

                    *** OCCUPATIONAL EXPOSURE LIMITS ***
 
   OEL-BELGIUM:TWA 0.05 mg/m3 JAN 1993
   
   OEL-DENMARK:TWA 0.05 mg/m3 JAN 1993
   
   OEL-FINLAND:TWA 0.1 mg/m3 JAN 1993
   
   OEL-FRANCE:TWA 10 mg/m3 JAN 1993
   
   OEL-GERMANY:TWA 0.15 mg/m3 JAN 1993
   
   OEL-SWEDEN:TWA 0.05 mg/m3 JAN 1993
   
   OEL-SWITZERLAND:TWA 0.15 mg/m3 JAN 1993
   
   OEL-THAILAND:TWA 10 mg/m3 JAN 1993
   
   OEL-UNITED KINGDOM:TWA 0.05 mg/m3 (resp. dust) JAN 1993
   
   OEL-UNITED KINGDOM:TWA 0.15 mg/m3 (total dust) JAN 1993
   
   OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV
   
   OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH RECOMMENDED EXPOSURE LEVEL (REL) :
   NIOSH REL TO SILICA, crystalline tridymite-air:10H CA TWA 0.05 mg/m3
REFERENCE :
   NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of
   Health, Education, and Welfare, Reports and Memoranda.
   Volume(issue)/page/year: DHHS #92-100,1992

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - 74617
       No. of Facilities: 21 (estimated)
       No. of Industries: 1
       No. of Occupations: 1
       No. of Employees: 2042 (estimated)
       No. of Female Employees: 351 (estimated)

                          *** STATUS IN U.S. ***
 
   NIOSH Analytical Method, 1994: Silica, crystalline, by XRD, 7500; by VIS,
   7600; by IR, 7602
   
   NTP 7th Annual Report on Carcinogens, 1992 : anticipated to be carcinogen
   
   OSHA ANALYTICAL METHOD #ID-125G

 
                            *** END OF RECORD ***