Thallium(I) acetate (cas 563-68-8) MSDS

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1.
1.1
IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING
Product identifiers
Product name
Product Number
Brand
Index-No.
CAS-No.
:
:
:
:
:
Thallium(I) acetate
T8266
081-002-00-9
563-68-8
1.2
Relevant identified uses of the substance or mixture and uses advised against
Identified uses
:
Laboratory chemicals, Manufacture of substances
2.
2.1
2.2
HAZARDS IDENTIFICATION
Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008 [EU-GHS/CLP]
Acute toxicity, Inhalation (Category 2)
Acute toxicity, Oral (Category 2)
Specific target organ toxicity - repeated exposure (Category 2)
Chronic aquatic toxicity (Category 2)
Classification according to EU Directives 67/548/EEC or 1999/45/EC
Very toxic by inhalation and if swallowed. Danger of cumulative effects. Toxic to aquatic organisms, may
cause long-term adverse effects in the aquatic environment.
Label elements
Labelling according Regulation (EC) No 1272/2008 [CLP]
Pictogram
Signal word
Hazard statement(s)
H300
H330
H373
H411
Precautionary statement(s)
P260
Danger
Fatal if swallowed.
Fatal if inhaled.
May cause damage to organs through prolonged or repeated exposure.
Toxic to aquatic life with long lasting effects.
Do not breathe dust/ fume/ gas/ mist/ vapours/ spray.
P264
P273
P284
P301 + P310
P310
Supplemental Hazard
Wash hands thoroughly after handling.
Avoid release to the environment.
Wear respiratory protection.
IF SWALLOWED: Immediately call a POISON CENTER or doctor/
physician.
Immediately call a POISON CENTER or doctor/ physician.
none
Statements
According to European Directive 67/548/EEC as amended.
Hazard symbol(s)
R-phrase(s)
R26/28
R33
R51/53
Very toxic by inhalation and if swallowed.
Danger of cumulative effects.
Toxic to aquatic organisms, may cause long-term adverse effects in the
aquatic environment.
S-phrase(s)
S13
S28
S45
S61
Keep away from food, drink and animal feedingstuffs.
After contact with skin, wash immediately with plenty of soap and water.
In case of accident or if you feel unwell, seek medical advice immediately
(show the label where possible).
Avoid release to the environment. Refer to special instructions/ Safety
data sheets.
2.3
3.
3.1
Other hazards - none
COMPOSITION/INFORMATION ON INGREDIENTS
Substances
Synonyms
Formula
Molecular Weight
Component
Thallium acetate
:
:
:
Acetic acidthallium(I) salt
C2H3O2Tl
263,43 g/mol
Concentration
CAS-No.
EC-No.
Index-No.
563-68-8
209-257-5
081-002-00-9
-
4.
4.1
FIRST AID MEASURES
Description of first aid measures
General advice
Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled
If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact
Wash off with soap and plenty of water. Take victim immediately to hospital. Consult a physician.
In case of eye contact
Flush eyes with water as a precaution.
If swallowed
Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
4.2
4.3
5.
5.1
5.2
5.3
5.4
6.
6.1
6.2
6.3
6.4
7.
7.1
7.2
7.3
Most important symptoms and effects, both acute and delayed
The most characteristic symptom of thallium exposure is alopecia (loss of hair). Cutaneous effects may
include dry, scaly skin and impairment of nail growth often resulting in the appearance of crescent-shaped
strips across fingernails and toenails (Mees' line). Other symptoms in acute poisoning relate chiefly to the
gastrointestinal tract, nervous system, skin, eyes, and cardiovascular system. Acute poisoning results in
swelling of the feet and legs, arthralgia, vomiting, insomnia, hyperesthesia and paresthesia of the hands
and feet, mental confusion, polyneuritis with severe pain in the legs and loins, partial paralysis of the legs,
angina-like pains, nephritis, wasting and weakness, and lymphocytosis and eosinophilia. In chronic
poisoning, central and peripheral nervous system abnormalities may persist including ataxia, tremor,
incoordination, paralysis of extremities, endocrine disorders, memory loss, and psychoses may develop.,
To the best of our knowledge, the chemical, physical, and toxicological properties have not been
thoroughly investigated.
Indication of any immediate medical attention and special treatment needed
no data available
FIREFIGHTING MEASURES
Extinguishing media
Suitable extinguishing media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, thallium oxides
Advice for firefighters
Wear self contained breathing apparatus for fire fighting if necessary.
Further information
no data available
ACCIDENTAL RELEASE MEASURES
Personal precautions, protective equipment and emergency procedures
Wear respiratory protection. Avoid dust formation. Avoid breathing vapors, mist or gas. Ensure adequate
ventilation. Evacuate personnel to safe areas. Avoid breathing dust.
Environmental precautions
Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the
environment must be avoided.
Methods and materials for containment and cleaning up
Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed
containers for disposal.
Reference to other sections
For disposal see section 13.
HANDLING AND STORAGE
Precautions for safe handling
Avoid contact with skin and eyes. Avoid formation of dust and aerosols.
Provide appropriate exhaust ventilation at places where dust is formed.
Conditions for safe storage, including any incompatibilities
Store in cool place. Keep container tightly closed in a dry and well-ventilated place.
hygroscopic
Specific end uses
no data available
8.
8.1
8.2
9.
9.1
EXPOSURE CONTROLS/PERSONAL PROTECTION
Control parameters
Components with workplace control parameters
Exposure controls
Appropriate engineering controls
Avoid contact with skin, eyes and clothing. Wash hands before breaks and immediately after handling
the product.
Personal protective equipment
Eye/face protection
Face shield and safety glasses Use equipment for eye protection tested and approved under
appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique
(without touching glove's outer surface) to avoid skin contact with this product. Dispose of
contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.
The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and
the standard EN 374 derived from it.
Body Protection
Complete suit protecting against chemicals, The type of protective equipment must be selected
according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection
Where risk assessment shows air-purifying respirators are appropriate use a full-face particle
respirator type N100 (US) or type P3 (EN 143) respirator cartridges as a backup to engineering
controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use
respirators and components tested and approved under appropriate government standards such
as NIOSH (US) or CEN (EU).
PHYSICAL AND CHEMICAL PROPERTIES
Information on basic physical and chemical properties
a)
b)
c)
d)
e)
f)
g)
h)
Appearance
Odour
Odour Threshold
pH
Melting point/freezing
point
Initial boiling point and
boiling range
Flash point
Evaporation rate
Form: solid
Colour: beige
no data available
no data available
no data available
Melting point/range: 126 °C
no data available
no data available
no data available
i)
Flammability (solid, gas) no data available
j)
k)
l)
Upper/lower
flammability or
explosive limits
Vapour pressure
Vapour density
no data available
no data available
no data available
m) Relative density
3,680 g/cm3
n)
o)
p)
q)
r)
s)
t)
Water solubility
Partition coefficient: n-
octanol/water
Autoignition
temperature
Decomposition
temperature
Viscosity
Explosive properties
Oxidizing properties
soluble
no data available
no data available
no data available
no data available
no data available
no data available
9.2
10.
10.1
10.2
10.3
10.4
10.5
10.6
11.
11.1
Other safety information
no data available
STABILITY AND REACTIVITY
Reactivity
no data available
Chemical stability
no data available
Possibility of hazardous reactions
no data available
Conditions to avoid
Heat.
Incompatible materials
Strong oxidizing agents, Strong acids
Hazardous decomposition products
Other decomposition products - no data available
TOXICOLOGICAL INFORMATION
Information on toxicological effects
Acute toxicity
LD50 Oral - rat - 41,3 mg/kg
Remarks: Behavioral:Convulsions or effect on seizure threshold. Gastrointestinal:Other changes. Blood:
Hemorrhage.
Skin corrosion/irritation
no data available
Serious eye damage/eye irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
Laboratory experiments have shown mutagenic effects.
Genotoxicity in vitro - Hamster - Embryo
Morphological transformation.
Carcinogenicity
This product is or contains a component that is probably not carcinogenic based on its IARC, ACGIH, NTP,
or EPA classification.
IARC:
No component of this product present at levels greater than or equal to 0.1% is identified as
probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity
Developmental Toxicity - rat - Oral
Specific Developmental Abnormalities: Musculoskeletal system.
Specific target organ toxicity - single exposure
no data available
Specific target organ toxicity - repeated exposure
no data available
Aspiration hazard
no data available
Potential health effects
Inhalation
Ingestion
Skin
Eyes
May be fatal if inhaled. May cause respiratory tract irritation.
May be fatal if swallowed.
May be harmful if absorbed through skin. May cause skin irritation.
May cause eye irritation.
Signs and Symptoms of Exposure
The most characteristic symptom of thallium exposure is alopecia (loss of hair). Cutaneous effects may
include dry, scaly skin and impairment of nail growth often resulting in the appearance of crescent-shaped
strips across fingernails and toenails (Mees' line). Other symptoms in acute poisoning relate chiefly to the
gastrointestinal tract, nervous system, skin, eyes, and cardiovascular system. Acute poisoning results in
swelling of the feet and legs, arthralgia, vomiting, insomnia, hyperesthesia and paresthesia of the hands
and feet, mental confusion, polyneuritis with severe pain in the legs and loins, partial paralysis of the legs,
angina-like pains, nephritis, wasting and weakness, and lymphocytosis and eosinophilia. In chronic
poisoning, central and peripheral nervous system abnormalities may persist including ataxia, tremor,
incoordination, paralysis of extremities, endocrine disorders, memory loss, and psychoses may develop.,
To the best of our knowledge, the chemical, physical, and toxicological properties have not been
thoroughly investigated.
Additional Information
RTECS: Not available
12.
12.1
ECOLOGICAL INFORMATION
Toxicity
Toxicity to fish
LC50 - Menidia beryllina - 31 mg/l - 96 h
12.2
12.3
12.4
12.5
12.6
13.
13.1
Persistence and degradability
no data available
Bioaccumulative potential
no data available
Mobility in soil
no data available
Results of PBT and vPvB assessment
no data available
Other adverse effects
Harmful to aquatic life.
no data available
DISPOSAL CONSIDERATIONS
Waste treatment methods
Product
Offer surplus and non-recyclable solutions to a licensed disposal company. Dissolve or mix the material
with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber.
Contaminated packaging
Dispose of as unused product.
14.
14.1
TRANSPORT INFORMATION
UN number
14.2
ADR/RID: 1707
UN proper shipping name
IMDG: 1707
IATA: 1707
ADR/RID:
IMDG:
IATA:
THALLIUM COMPOUND, N.O.S. (Thallium acetate)
THALLIUM COMPOUND, N.O.S. (Thallium acetate)
Thallium compound, n.o.s.
14.3
Transport hazard class(es)
14.4
14.5
14.6
15.
ADR/RID: 6.1
Packaging group
ADR/RID: II
Environmental hazards
ADR/RID: yes
Special precautions for user
no data available
REGULATORY INFORMATION
IMDG: 6.1
IMDG: II
IMDG Marine pollutant: yes
IATA: 6.1
IATA: II
IATA: no
This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
15.1
15.2
16.
Safety, health and environmental regulations/legislation specific for the substance or mixture
no data available
Chemical Safety Assessment
no data available
OTHER INFORMATION
Further information
The above information is believed to be correct but does not purport to be all inclusive and
shall be used only as a guide. The information this document is based on the resent state
of our knowledge and is applicable to the product with regard to appropriate safety precautions.
It does not represent any guarantee of the properties of the product. guidechem shall not be
held liable for any damage resulting from handling or from contact with the above product.
See reverse side of invoice or packing slip for additional terms and conditions of sale.