Related Searches: Fludarabine phosphate, fludarabine phosphate 75607-67-9, phosphate, phosphate potassium phosphate, dihydrogen phosphate, View all

Fludarabine phosphate(CAS No. 75607-67-9)

Fludarabine phosphate C10H13FN5O7P (cas 75607-67-9) Molecular Structure

75607-67-9 Structure

Identification and Related Records

【Name】
Fludarabine phosphate
【Iupac name】
[(2R,3S,4S,5R)-5-(6-amino-2-fluoropurin-9-yl)-3,
4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate
【CAS Registry number】
75607-67-9
【Synonyms】
Fludarabine phosphate (JAN/USP)
Fludarabine 5-monophosphate
9-beta-D-Arabinofuranosyl-2-fluoroadenine 5-(dihydrogen phosphate)
Trimeric Sodium Phosphate
[(2R,3R,4S,5R)-5-(6-amino-2-fluoro-purin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxyphosphonic acid
2-Fluoro-ARA AMP
Fludarabine phosphate [USAN:BAN]
Fludarabine monophosphate
9-beta-Arabinofuranosyl-2-fluoroadenine-5-phosphate
Fludura
9H-Purin-6-amine, 2-fluoro-9-(5-O-phosphono-.beta.-D-arabinofuranosyl)-
2-Fluoroadenine arabinoside 5-monophosphate
fludarabine hcl
【Molecular Formula】
C10H13FN5O7P (Products with the same molecular formula)
【Molecular Weight】
365.21
【Inchi】
InChI=1/C10H13FN5O7P/c11-10-14-7(12)4-8(15-10)16(2-13-4)9-6(18)5(17)3(23-9)1-22-24(19,20)21/h2-3,5-6,9,17-18H,1H2,(H2,12,14,15)(H2,19,20,21)/t3-,5-,6+,9-/m1/s1
【Canonical SMILES】
C1=NC2=C(N1C3C(C(C(O3)COP(=O)(O)O)O)O)N=C(N=C2N)F
【Isomers smiles】
C1=NC2=C(N1[C@H]3[C@H]([C@@H]([C@H](O3)COP(=O)(O)O)O)O)N=C(N=C2N)F
【MOL File】
75607-67-9.mol

Chemical and Physical Properties

【Density】
2.39 g/cm3
【Boiling Point】
864.2 oC at 760 mmHg
【Refractive Index】
1.878
【Flash Point】
476.4 oC
【Computed Properties】
Molecular Weight:365.211684 [g/mol]
Molecular Formula:C10H13FN5O7P
XLogP3:-3.1
H-Bond Donor:5
H-Bond Acceptor:8
Rotatable Bond Count:4
Tautomer Count:3
Exact Mass:365.053663
MonoIsotopic Mass:365.053663
Topological Polar Surface Area:186
Heavy Atom Count:24
Formal Charge:0
Complexity:514
Isotope Atom Count:0
Defined Atom Stereocenter Count:4
Undefined Atom Stereocenter Count:0
Defined Bond Stereocenter Count:0
Undefined Bond Stereocenter Count:0
Covalently-Bonded Unit Count:1
Feature 3D Acceptor Count:6
Feature 3D Donor Count:3
Feature 3D Anion Count:1
Feature 3D Cation Count:4
Feature 3D Ring Count:3
Effective Rotor Count:5
Conformer Sampling RMSD:0.8
CID Conformer Count:50

Safety and Handling

【Specification】

? Fludarabine phosphate (CAS NO.75607-67-9), its Synonyms are Fludarabine monophosphate ; 2-Fluoro-9-(5-O-phosphono-beta-D-arabinofuranosyl)-9H-purin-6-amine ; 2-Fluoro-ARA AMP ; 2-Fluoroadenine arabinoside 5'-monophosphate ; 9-beta-Arabinofuranosyl-2-fluoroadenine-5'-phosphate ; 9-beta-D-Arabinofuranosyl-2-fluoroadenine 5'-(dihydrogen phosphate) ; 9-beta-D-Arabinofuranosyl-2-fluoroadenine 5'-monophosphate ; Fludara ; 9H-Purin-6-amine, 2-fluoro-9-(5-O-phosphono-beta-D-arabinofuranosyl)- .

Biomedical Effects and Toxicity

【Pharmacological Action】
- Antimetabolites that are useful in cancer chemotherapy.
- Agents that suppress immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-CELLS or by inhibiting the activation of HELPER CELLS. While immunosuppression has been brought about in the past primarily to prevent rejection of transplanted organs, new applications involving mediation of the effects of INTERLEUKINS and other CYTOKINES are emerging.

Supplier Location

Top Suppliers

Diamond member Hangzhou Kaipeng Biotechnology Co., Ltd.
Country:ChinaChina
Business Type:Manufacturer
Telephone:86-571-89939007
Diamond member Jinlan Pharm-Drugs Technology Co., Limited
Country:ChinaChina
Business Type:Manufacturer
Telephone:86-571-85829152
Diamond member Hubei XinRunde Chemical Co., Ltd
Country:ChinaChina
Business Type:Manufacturer
Telephone:86-188-74586545
Diamond member Nanjing Bangnuo Biotechnology Co., Ltd.
Country:ChinaChina
Business Type:Manufacturer
Telephone:86-25-52178272
Diamond member Shanghai Do Chemical Co.,Ltd
Country:ChinaChina
Business Type:Manufacturer
Telephone:86-21-33758180
Diamond member Hangzhou Dayangchem Co., Ltd.
Country:ChinaChina
Business Type:Manufacturer
Telephone:86-571-88938639
Diamond member Wuhan Fortuna Chemical Co., Ltd.
Country:ChinaChina
Business Type:Manufacturer
Telephone:0086-27-59207850
Diamond member AOPHARM
Country:ChinaChina
Business Type:Manufacturer
Telephone:86-311-66600578
Diamond member Nanjing Chemlin Chemical Co., Ltd.
Country:ChinaChina
Business Type:Manufacturer
Telephone:86-25-83697070
Diamond member Hangzhou J&H Chemical Co., Ltd
Country:ChinaChina
Business Type:Manufacturer
Telephone:86-571-87396430

Quick Search

Cas    Name

Related products

Fludarabine Phosphate iMpurity B

Fludarabine Phosphate iMpurity B

Phosphate

O-Phosphate;Orthophosphate;Phosphate ions;

PHOSPHATE

Isooctanol, reaction products with phosphorus oxide (p2o5) and polyethylene glycol monotridecyl ether

Histamine phosphate

Histamine acid phosphate;1H-Imidazole-4-ethanamine,compounds,phosphate (1:2);Histamine Diphosphate;Histamine bisphosphate monohydrate;

Triethyl phosphate

Ethyl phosphate; Triethyl Phosphate (TEP); Triethylphosphatecolorlessliq; Phosphoric acid triethyl ester; TEP; Flame retardant-TEP; BHGUARD-TEP

Dibutyl Phosphate

Phosphoricaciddibutylester; PHOSPHORIC ACID DIBUTYL ESTER

Triphenyl phosphate

triphenyl phosphate free of phenol; Triphenyl Phosphate (TPPa); Triphenyl phosphate white xtl; Phosphoric acid triphenyl ester; TPP

Pyridoxine phosphate

Pyridoxol, 5-(dihydrogen phosphate)(6CI,7CI,8CI); Pyridoxine 5-phosphate; Pyridoxine 5'-phosphate;3,4-Pyridinedimethanol,5-hydroxy-6-methyl-, 3-(dihyd...

Trioleyl phosphate

9-Octadecen-1-ol, phosphate (3:1), (Z,Z,Z)-; Hostaphat KO 300