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Pioglitazone hydrochloride(CAS No. 112529-15-4)

Pioglitazone hydrochloride C19H21ClN2O3S (cas 112529-15-4) Molecular Structure

112529-15-4 Structure

Identification and Related Records

【Name】
Pioglitazone hydrochloride
【Iupac name】
5-[[4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl]methyl]-1,3-thiazolidine-2,
4-dione hydrochloride
【CAS Registry number】
112529-15-4
【Synonyms】
(+-)-5-(p-(2-(5-Ethyl-2-pyridyl)ethoxy)benzyl)-2,4-thiazolidinedione monohydrochloride
Actos
2,4-Thiazolidinedione,5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-, monohydrochloride (9CI)
2,4-Thiazolidinedione, 5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-,monohydrochloride, (?à)-
5-[4-[2-(5-Ethyl-2-pyridyl)ethoxy]benzyl]thiazolidine-2,4-dionehydrochloride
Pioglitazone HCl
【Molecular Formula】
C19H21ClN2O3S (Products with the same molecular formula)
【Molecular Weight】
392.89964
【Inchi】
InChI=1S/C19H20N2O3S.ClH/c1-2-13-3-6-15(20-12-13)9-10-24-16-7-4-14(5-8-16)11-17-18(22)21-19(23)25-17;/h3-8,12,17H,2,9-11H2,1H3,(H,21,22,23);1H
【InChIKey】
GHUUBYQTCDQWRA-UHFFFAOYSA-N
【Canonical SMILES】
CCC1=CN=C(C=C1)CCOC2=CC=C(C=C2)CC3C(=O)NC(=O)S3.Cl
【MOL File】
112529-15-4.mol

Chemical and Physical Properties

【Appearance】
white crystals or crystalline powder
【Density】
1.26 g/cm3
【Melting Point】
193-194 oC
【Boiling Point】
575.4 oC at 760 mmHg
【Vapour】
0mmHg at 25°C
【Flash Point】
301.8 oC
【Water】
It is soluble in N,N-dimethylformamide, slightly soluble in anhydrous ethanol, very slightly soluble in acetone and acetonitrile, practically insoluble in water, and insoluble in ether
【Solubilities】
It is soluble in N,N-dimethylformamide, slightly soluble in anhydrous ethanol, very slightly soluble in acetone and acetonitrile, practically insoluble in water, and insoluble in ether
【Computed Properties】
Molecular Weight:392.89964 [g/mol]
Molecular Formula:C19H21ClN2O3S
H-Bond Donor:2
H-Bond Acceptor:5
Rotatable Bond Count:7
Tautomer Count:10
Exact Mass:392.096141
MonoIsotopic Mass:392.096141
Topological Polar Surface Area:93.6
Heavy Atom Count:26
Formal Charge:0
Complexity:466
Isotope Atom Count:0
Defined Atom Stereocenter Count:0
Undefined Atom Stereocenter Count:1
Defined Bond Stereocenter Count:0
Undefined Bond Stereocenter Count:0
Covalently-Bonded Unit Count:2

Safety and Handling

【Hazard Codes】
Xi:Irritant
【Risk Statements】
R36/38
【Safety Statements 】
22-24/25
【HazardClass】
IRRITANT
【Safety】

Hazard Codes:?IrritantXi
Risk Statements: 36/38?
R36/38: Irritating to eyes and skin.
Safety Statements of Pioglitazone HCl (CAS NO.112529-15-4): 22-24/25?
S22: Do not breathe dust.?
S24/25: Avoid contact with skin and eyes.

【Specification】

? Pioglitazone HCl (CAS NO.112529-15-4), its Synonyms are 2,4-Thiazolidinedione, 5-((4-(2-(5-ethyl-2-pyridinyl)ethoxy)phenyl)methyl)-, monohydrochloride, (+-)- ; (+-)-5-(p-(2-(5-Ethyl-2-pyridyl)ethoxy)benzyl)-2,4-thiazolidinedione monohydrochloride ; Pioglitazone hydrochloride ; Actos . It is colourless prisms.

Use and Manufacturing

【Usage】

Used as an antidiabetic

Biomedical Effects and Toxicity

【Pharmacological Action】
- Substances which lower blood glucose levels.

Supplier Location

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Telephone:0086-27-59207850
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