Related Searches: Basic Violet 3, basic violet, basic violet 1, basic violet 7, violet, View all

Basic Violet 3(CAS No. 548-62-9)

Basic Violet 3 C25H30ClN3 (cas 548-62-9) Molecular Structure

548-62-9 Structure

Identification and Related Records

【Name】
Basic Violet 3
【CAS Registry number】
548-62-9
【Synonyms】
Hexamethyl-p-rosaniline hydrochloride
NCI-C55969
Bismuth Violet
Genapax (TN)
PYOVERM
Methylrosanilinium chloride
Paper Blue R
Crystal Violet AON
Crystal Violet 6BO
[4-[bis(4-dimethylaminophenyl)methylidene]-1-cyclohexa-2,5-dienylidene]-dimethyl-azanium
Methyl Violet 6B (biological stain)
Violet CP
Crystal Violet 10B
Meroxylan-Wander
Crystal Violet Extra Pure APN
12416 Violet
Methylrosanilinium chloride (JP14)
Pyoktanin
Crystal Violet SS
Crystal Violet chloride
CI 42555
Crystal Violet FN
Crystal Violet BP
[4-[bis(4-dimethylaminophenyl)methylidene]-1-cyclohexa-2,5-dienylidene]-dimethyl-azanium chloride
Methyl Violet 10BO
Crystal Violet Extra Pure
Aizen Crystal Violet Extra Pure
Oxycolor
Crystal Violet chloride salt
C.I. 42555
Crystal Violet AO
Violet XXIII
Crystal Violet USP
Methyl Violet 6B
Crystal Violet HL2
Pararosaniline, N,N,N,N,N,N-hexamethyl-, chloride
Ammonium, [4-[bis[p-(dimethylamino)phenyl]methylene]-2, 5-cyclohexadien-1-ylidene]dimethyl-, chloride
Gentersal
Crystal Violet Pure DSC Brilliant
Crystal violet (C.I. 42555)
Gentian violet (USP)
Hexamethylpararosaniline chloride
Viocid
Methyl Violet 10BNS
Vermicid
Adergon
Methyl Violet 10BK
Avermin
Mitsui Crystal Violet
Axuris
KRISTALL-VIOLETT
Crystal Violet BPC
Methyl Violet 5BO
Atmonil
Plastoresin Violet 5BO
Oxyozyl
Crystal Violet Pure DSC
Aizen Crystal Violet
Badil
【EINECS(EC#)】
208-953-6
【Molecular Formula】
C25H30ClN3 (Products with the same molecular formula)
【Molecular Weight】
407.98
【Inchi】
InChI=1/C25H30N3.ClH/c1-26(2)22-13-7-19(8-14-22)25(20-9-15-23(16-10-20)27(3)4)21-11-17-24(18-12-21)28(5)6;/h7-18H,1-6H3;1H/q+1;/p-1
【Canonical SMILES】
CN(C)C1=CC=C(C=C1)C(=C2C=CC(=[N+](C)C)C=C2)C3=CC=C(C=C3)N(C)C.[Cl-]
【MOL File】
548-62-9.mol

Chemical and Physical Properties

【Appearance】
dark green powder or crystals
【Density】
1.19 g/cm3 (20 C)
【Melting Point】
215℃
【Flash Point】
40°C
【Water】
16 g/L (25℃)
【Solubilities】
16 g/L (25 oC)
【Color/Form】
Dark green powder or greenish, glistening pieces with metallic luster
Green powder
【Stability】
Stable. Incompatible with strong oxidizing agents, strong acids. Light-sensitive. Combustible.
【HS Code】
32041300
【Storage temp】
Store at RT.
【Spectral properties】
UV max of 590 nm in water
【Computed Properties】
Molecular Weight:407.9788 [g/mol]
Molecular Formula:C25H30ClN3
H-Bond Donor:0
H-Bond Acceptor:3
Rotatable Bond Count:4
Exact Mass:407.212826
MonoIsotopic Mass:407.212826
Topological Polar Surface Area:9.5
Heavy Atom Count:29
Formal Charge:0
Complexity:542
Isotope Atom Count:0
Defined Atom Stereocenter Count:0
Undefined Atom Stereocenter Count:0
Defined Bond Stereocenter Count:0
Undefined Bond Stereocenter Count:0
Covalently-Bonded Unit Count:2

Safety and Handling

【Hazard Codes】
T:Toxic
【Risk Statements】
R22;R41;R45;R50/53
【Safety Statements 】
S45;S53;S60;S61
【HazardClass】
9
【Safety】

Safety Information of Aniline violet (CAS NO.548-62-9):
Hazard Codes:Xn? ,N? ,T? ,C
Risk Statements: 52/53-50-45-41-22-40-34-10-36/37/38-23/25?
R52/53:Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment.?
R50: Very toxic to aquatic organisms.?
R45: May cause cancer.?
R41: Risk of serious damage to the eyes.?
R22: Harmful if swallowed.?
R40: Limited evidence of a carcinogenic effect.?
R34: Causes burns.?
R10: Flammable.?
R36/37/38: Irritating to eyes, respiratory system and skin.?
R23/25: Toxic by inhalation and if swallowed.
Safety Statements: 61-60-53-45-46-36/37/39-26-16-22?
S61: Avoid release to the environment. Refer to special instructions / safety data sheets.?
S60: This material and its container must be disposed of as hazardous waste.?
S53: Avoid exposure - obtain special instructions before use.?
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)?
S46: If swallowed, seek medical advice immediately and show this container or label.?
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S16: Keep away from sources of ignition.?
S22: Do not breathe dust.
RIDADR:UN 3077 9/PG 3
WGK Germany:3
RTECS:BO9000000
HazardClass:9
PackingGroup:III
HS Code:32041300
Poison by ingestion, intravenous, and intraperitoneal routes. An experimental teratogen. Other experimental reproductive effects. A human skin irritant. Human mutation data reported. Questionable carcinogen with experimental carcinogenic data. When heated to decomposition it emits very toxic fumes of NOx and Cl?.

【PackingGroup 】
III
【Skin, Eye, and Respiratory Irritations】
A human skin irritant.
【Cleanup Methods】
IN WATER & BUFFERED WATER SAMPLES CRYSTAL VIOLET WAS DECOMP & DECOLORIZED BY PHOTOLYSIS & RADIOLYSIS.
1.5 G OF WATER-INSOLUBLE POLY-N-VINYLPYRROLIDONE ADSORBENT WAS ADDED TO 15 ML WASTE WATER (ABSORBANCE 28.4) CONTAINING CRYSTAL VIOLET AT 20 DEG, AND AFTER AGITATING THE WASTE WATER WAS SETTLED FOR 2 HR AND CENTRIFUGED TO REMOVE PPTD MATERIALS.
【Transport】
UN 3077
【Formulations/Preparations】
Commercial product, which is usually admixed with pentamethylpararosaniline chloride and tetramethylpararosaniline chloride, contains not less than 96% gentian violet.
GENTIAN VIOLET TOPICAL SOLN, USP, CONTAINS 1% OF THE DRUG IN 10% ETHANOL, & GENTIAN VIOLET CREAM, USP, CONTAINS 1.35% IN AN ABSORBABLE BASE.
【Exposure Standards and Regulations】
The Approved Drug Products with Therapeutic Equivalence Evaluations List identifies currently marketed prescription drug products, incl gentian violet, approved on the basis of safety and effectiveness by FDA under sections 505 of the Federal Food, Drug, and Cosmetic Act.
【Protective Equipment and Clothing】
A human skin irritant.
【Specification】

Synonyms of Aniline violet (CAS NO.548-62-9):?4-(Bis(p-(dimethylamino)phenyl)methylene)-2,5-cyclohexadien-1-ylidene)dimethylammonium chloride ; Adergon ; Aizen Crystal Violet Extra Pure ; Aniline Violet ; Atmonil ; Basic Violet 3 ; Bismuth Violet ; Blaues pyoktanin Brilliant Violet 5B ; Calcozine Violet 6BN ; Chlorure de methylrosanilinum ; Cloruro de metilrosanilina ; Crystal Violet ; Genapax ; Gentersal ; Gentian Violet ; Gentianaviolett ; Genticid ; Gentioletten ; Hectograph Violet SR ; Hexamethyl Violet ; Hexamethyl p-rosaniline hydrochloride ; Hidaco Brilliant Crystal Violet ; Kristall-violett ;
?Meroxyl ; Meroxylan-wander ; Methyl Violet 6B (biological stain) ; Methylrosanilinchlorid ; Methylrosanilinii chloridum ;
?Methylrosanilinum chloratum ; Methylviolett ; Metilrosanilinio cloruro ; Pyoverm ; Vermicid ; Vianin ; Violet zasadita 3 .
First Aid Measures of Aniline violet (548-62-9):
Ingestion:Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Skin:Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Eyes:Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Storage of Aniline violet (CAS NO.548-62-9):
Keep away from heat, sparks, and flame. Store in a cool, dry place. Keep containers tightly closed. Store protected from light.

【Octanol/Water Partition Coefficient】
log Kow = 0.51 [Tsai R et al; J Chromatogr 538: 119-23 (1991)] PubMed Abstract
【Report】

Reported in EPA TSCA Inventory.

【Disposal Methods】
SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.
Incineration: 1) Dissolve in such combustible solvent as alcohols, etc. Spray the soln into the furnace with afterburner and scrubber. 2) Pour into sodium bicarbonate or a mixture of sand and Na2CO3 /sodium carbonate/ (9:1). After mixing, transfer into a paper carton filled with packing paper. Burn in an open furnace, or more efficiently in the furnace with afterburner and scrubber.

Use and Manufacturing

【Use and Manufacturing】
Methods of Manufacturing

SEVERAL PROCESSES ARE AVAIL FOR THE PRODUCTION OF "ROSANILINES" WHICH REPRESENT A LARGE CLASS OF DYESTUFFS. THEY ARE GENERALLY MADE BY OXIDIZING A MIXTURE OF ANILINE & P-TOLUIDINE. OXIDIZING AGENT MOST COMMONLY USED IS ARSENIC ACID. NITROBENZENE IS ALSO EMPLOYED. BY USING METHYLATED ANILINES, EG, DI- OR MONOMETHYLANILINE, METHYLROSANILINES ARE PRODUCED. PURE HEXAMETHYLROSANILINE MAY BE MADE BY THE ACTION OF CARBONYL CHLORIDE (PHOSGENE) ON N,N-DIMETHYLANILINE.
Consumption Patterns

(1993) 459,000 kg
【Usage】

Acid base indicator, denaturant for alc, biological stain, dye for textiles, pigments.

Biomedical Effects and Toxicity

【Pharmacological Action】
- Substances used on humans and other animals that destroy harmful microorganisms or inhibit their activity. They are distinguished from DISINFECTANTS, which are used on inanimate objects.
【Therapeutic Uses】
Anti-Infective Agents, Local; Antinematodal Agents; Rosaniline Dyes
/Former/ ...MAY BE USED FOR INFECTED WOUNDS, MUCOUS MEMBRANES, & SEROUS SURFACES.
/Former/ ...ACTS AGAINST THE CAUSATIVE ORGANISM OF VINCENT'S ANGINA & AGAINST MANY STRAINS OF MONILIA, TORULA, EPIDERMOPHYTON, & TRICHOPHYTON. AMONG THE MANY CONDITIONS WHICH HAVE BEEN TREATED...VINCENT'S ANGINA, CYSTITIS & URETHRITIS, SUPPURATING JOINT INFECTIONS, ECZEMATOID DERMATITIS, FURUNCULOSIS, RECURRENT DERMATOMYCOSIS, MONILIAL PARONYCHIA, CHRONIC ULCERS, BED SORES, IMPETIGO, PRURITUS ANI, LEUKORRHEA & VAGINITIS, ETC. THE DRUG HAS BEEN LARGELY OUTMODED BY ANTIBIOTICS & SYSTEMIC ANTIBACTERIAL DRUGS, NOT SO MUCH BECAUSE OF ITS INEFFICACY BUT BECAUSE OT ITS COSMETIC EFFECTS & STAINING OF CLOTHING.
/Former/ THE DYE HAS BEEN EMPLOYED IN THE TREATMENT OF BURNS. THIS FORMS A PLIABLE ESCHAR & HELPS TO CONTROL INFECTION FROM GRAM-POS ORGANISMS. HOWEVER, IT IS LITTLE USED TODAY FOR THIS PURPOSE. GENTIAN VIOLET IS...AN EFFECTIVE ANTHELMINTIC USEFUL IN THE TREATMENT OF STRONGYLOIDES & OXYURIS INFESTATIONS.
GENTIAN VIOLET IS BACTERIOSTATIC & BACTERICIDAL TO GRAM-POS BACTERIA & TO MANY FUNGI. GRAM-NEG & ACID-FAST BACTERIA ARE VERY RESISTANT TO THE DRUG. ...ONCE WIDELY EMPLOYED IN THE CONTROL OF MANY TYPES OF INFECTIONS. IT HAS BEEN USED FOR SUPERFICIAL PYOGENIC INFECTIONS, IMPETIGO, VINCENT'S INFECTION, & CHRONIC & IRRITATIVE LESIONS & DERMATITIDES. IT IS STILL OCCASIONALLY EMPLOYED IN TREATMENT OF FUNGAL INFECTIONS. FOR DIRECT APPLICATION TO TISSUES, THE DYE IS USED IN CONCN OF 0.02% TO 1%. VAGINAL SUPPOSITORIES CONTAIN 17 MG, WHILE VAGINAL TABLETS CONTAIN 2 MG. FOR INSTILLATIONS IN CLOSED CAVITIES, THE CONCN IS REDUCED TO 0.01%.
Anti-infective (topical). Has been used as anthelmintic (Nematodes).
THERAP CAT (VET): Antimicrobial (topical)
【Biomedical Effects and Toxicity】
NINE MALE & 9 FEMALE HUBBARD ADULT BROILER BREEDERS WERE USED TO STUDY TISSUE RESIDUES OF GENTIAN VIOLET, EACH BIRD WAS GIVEN (14)C-GENTIAN VIOLET ORALLY. T/2 OF RADIOACTIVITY FROM (14)C-GENTIAN VIOLET IN BLOOD DIFFERED BETWEEN SEXES (1.43 HR & 1.68 HR FOR MALES & FEMALES, RESPECTIVELY). AT 8 HR AFTER ADMIN ONLY 1 BIRD HAD DETECTABLE AMT OR RADIOACTIVITY IN MUSCLE. DETECTABLE LEVELS OF RADIOACTIVITY WERE FOUND IN LIVER @ 120 HR AFTER DOSING & IN KIDNEY @ 432 HR AFTER DOSING. ALL EGGS COLLECTED DURING 1ST 144 HR CONTAINED VERY LOW BUT DETECTABLE LEVELS OF RADIOACTIVITY.

Environmental Fate and Exposure Potential

【Environmental Fate/Exposure Summary】
TERRESTRIAL FATE: Based on a classification scheme(1), an estimated Koc value of 4X10+6(SRC), determined from a structure estimation method(2), indicates that hexamethyl-p-rosaniline chloride is expected to immobile in soil(SRC). Hexamethyl-p-rosaniline chloride is a cationic salt(5) and cations generally adsorb to organic carbon and clay more strongly than their neutral counterparts(6). Volatilization of hexamethyl-p-rosaniline chloride from moist soil surfaces is not expected to be an important fate process(SRC) given an estimated Henry's Law constant of 3.1X10-16 atm-cu m/mole(SRC), using a fragment constant estimation method(3). Hexamethyl-p-rosaniline chloride is not expected to volatilize from dry soil surfaces(SRC) based upon an estimated vapor pressure of 1.9X10-14 mm Hg(SRC), determined from a fragment constant method(4).
AQUATIC FATE: Based on a classification scheme(1), an estimated Koc value of 4X10+6(SRC), determined from a structure estimation method(2), indicates that hexamethyl-p-rosaniline chloride is expected to adsorb to suspended solids and sediment(SRC). Volatilization from water surfaces is not expected(3) based upon an estimated Henry's Law constant of 3.1X10-16 atm-cu m/mole(SRC), developed using a fragment constant estimation method(4). Hexamethyl-p-rosaniline chloride is a cationic salt(5) and cations generally adsorb to organic carbon and clay more strongly than their neutral counterparts(6). According to a classification scheme(7), an estimated BCF of 3.2(SRC), from an estimated log Kow of 0.5(8) and a regression-derived equation(9), suggests the potential for bioconcentration in aquatic organisms is low(SRC). Hexamethyl-p-rosaniline chloride had measurable transformation rates (0.002 to 0.012/hour) in 42 batch culture die-away tests using water samples obtained from four North Georgia sites - a river, two sites in a large lake, and a eutrophic pond(10); these transformation rates correspond to a half-life range of 2.4 to 14.4 days(SRC). The photoreaction of hexamethyl-p-rosaniline chloride in water is reported to give p-dimethylamino phenol, 4,4'-bis dimethylamino benzophenone, the leuco and demethylated derivative of hexamethyl-p-rosaniline chloride(11).
ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), hexamethyl-p-rosaniline chloride, which has an estimated vapor pressure of 1.9X10-14 mm Hg at 25 deg C(SRC), determined from a fragment constant method(2), is expected to exist solely in the particulate phase in the ambient atmosphere. Particulate-phase hexamethyl-p-rosaniline chloride may be removed from the air by wet and dry deposition(SRC). Hexamethyl-p-rosaniline chloride has a UV max of 590 nm(3) indicating a potential for direct photolysis in the environment(SRC).

Supplier Location

Top Suppliers

Diamond member Hangzhou Dayangchem Co., Ltd.
Country:ChinaChina
Business Type:Manufacturer
Telephone:86-571-88938639
Diamond member Hubei XinRunde Chemical Co., Ltd
Country:ChinaChina
Business Type:Manufacturer
Telephone:86-188-74586545
Diamond member Wuhan Fortuna Chemical Co., Ltd.
Country:ChinaChina
Business Type:Manufacturer
Telephone:0086-27-59207850
Diamond member MOSINTER GROUP LIMITED
Country:ChinaChina
Business Type:Manufacturer
Telephone:86-574-89212210
Diamond member Hangzhou J&H Chemical Co., Ltd
Country:ChinaChina
Business Type:Manufacturer
Telephone:86-571-87396430
Wuhan Dahua Weiye Pharmaceutical Co.,Ltd
Country:ChinaChina
Business Type:Manufacturer
Telephone:86-27-59262863
Hubei Yuancheng Saichuang Technology Co., Ltd
Country:ChinaChina
Business Type:Manufacturer
Telephone:86-27-68886732
Jinan Haohua Industry Co., Ltd.
Country:ChinaChina
Business Type:Manufacturer
Telephone:0086-531-58773055
Wuhan Senwayer Century chemical Co.,Ltd
Country:ChinaChina
Business Type:Manufacturer
Telephone:86-27-59009407
Tianjin Incentive Technology Co., Ltd
Country:ChinaChina
Business Type:Trading Company
Telephone:86-22-82826443

Quick Search

Cas    Name

Related products

Basic Violet 11:1

3,6-Bis(diethylamino)-9-(2-(methoxycarbonyl)phenyl)xanthylium tetrachlorozincate;

Basic Violet 14

Benzenamine,4-[(4-aminophenyl)(4-imino-2,5-cyclohexadien-1-ylidene)methyl]-2-methyl-,monohydrochloride (9CI); C.I. Basic Violet 14, monohydrochloride ...

C.I. Basic Violet 35

BasacrylViolet FL; Basic Violet 35

C.I. Basic Violet 27

AizenCathilon Red 7BNH; Basic Violet 27

C.I. Basic violet 15

C.I. Basic violet 15

C.I. Basic violet 37

C.I. Basic violet 37

Basic Violet 8

C.I. Basic Violet 8

C.I. Basic Violet 1,molybdatesilicate

Molybdatesilicate,salt with C.I. Basic Violet 1 (9CI); Benzenamine, 4-[(4-aminophenyl)(4-imino-2,5-cyclohexadien-1-ylidene)methyl]-,N-Me derivs., moly...

C.I. Basic Violet 20(9CI)

AstrazonViolet FRR; Basic Violet 20