Norandrostenedione(CAS No. 734-32-7)

Norandrostenedione C18H24O2 (cas 734-32-7) Molecular Structure

734-32-7 Structure

Identification and Related Records

【Name】
Norandrostenedione
【CAS Registry number】
734-32-7
【Synonyms】
(+)-19-Norandrost-4-en-3,17-dione
(+)-19-Norandrost-4-ene-3,17-dione
(+)-Estr-4-ene-3,17-dione
19-Nor-4-androstenedione
19-Norandrost-4-ene-3,17-dione
3,17-Dioxo-19-norandrost-4-ene
NSC 12164
Nordione
d-19-Norandrost-4-ene-3,17-dione
【EINECS(EC#)】
211-995-8
【Molecular Formula】
C18H24O2 (Products with the same molecular formula)
【Molecular Weight】
272.38
【Inchi】
InChI=1/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h10,13-16H,2-9H2,1H3/t13-,14+,15+,16-,18-/m0/s1
【MOL File】
734-32-7.mol

Chemical and Physical Properties

【Density】
1.13 g/cm3
【Melting Point】
169-172°C
【Boiling Point】
433.4 °C at 760 mmHg
【Refractive Index】
1.556
【Flash Point】
433.4 °C at 760 mmHg
【Storage temp】
Refrigerator

Safety and Handling

【Hazard Codes】
F, C
【Risk Statements】
R11
【Safety Statements 】
16-26-36/37/39-45
【Safety】
Hazard Codes:F,C
Risk Statements:11-34
11:Highly Flammable
34:Causes burns
Safety Statements:16-26-36/37/39-45
16:Keep away from sources of ignition - No smoking
26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36/37/39:Wear suitable protective clothing, gloves and eye/face protection
45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
WGK Germany:3
【Specification】

The IUPAC name of Estr-4-ene-3,17-dione is (8R,9S,10R,13S,14S)-13-methyl-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthrene-3,17-dione . With the CAS registry number 734-32-7, it is also named as 19-Norandrostenedione ; NSC 12164 ; delta4-Estrene-3,17-dione . The product's categories are steroids, miscellaneous biochemicals, intermediates & fine chemicals and pharmaceuticals.

The Estr-4-ene-3,17-dione is used as Norethindrone intermediate. It was available without prescription in United States until 2005. It was marketed as a prohormone in United States, but it is now classified as a Schedule III drug. Estr-4-ene-3,17-dione is readily metabolized to nandrolone after oral administration, but its potency to transactivate the androgen receptor dependent reporter gene expression is 10 times lower as compared to dihydrotestosterone (DHT).

This product is highly flammable. It can cause burns. Keep away from sources of ignition. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. If you want to contact this product, you must wear suitable protective clothing, gloves and eye/face protection. In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)

The other characteristics of this product can be summarized as: (1)ACD/LogP: 2.42 ; (2)# of Rule of 5 Violations: 0 ; (3)ACD/LogD (pH 5.5): 2.42 ; (4)ACD/LogD (pH 7.4): 2.42 ; (5)ACD/BCF (pH 5.5): 40.49 ; (6)ACD/BCF (pH 7.4): 40.49 ; (7)ACD/KOC (pH 5.5): 492.24 ; (8)ACD/KOC (pH 7.4): 492.24 ; (9)#H bond acceptors: 2 ; (10)Index of Refraction: 1.555 ; (11)Molar Refractivity: 77.05 cm3 ; (12)Molar Volume: 239.8 cm3 ; (13)Polarizability: 30.54×10-24 cm3 ; (14)Surface Tension: 43.3 dyne/cm ; (15)Enthalpy of Vaporization: 68.94 kJ/mol ; (16)Vapour Pressure: 1.03E-07 mmHg at 25°C ; (17)Tautomer Count: 16 ; (18)Exact Mass: 272.17763 ; (19)MonoIsotopic Mass: 272.17763 ; (20)Topological Polar Surface Area: 34.1 ; (21)Heavy Atom Count: 20.

People can use the following data to convert to the molecule structure. SMILES: O=C4/C=C3/CC[C@@H]2[C@H](CC[C@@]1(C(=O)CC[C@H]12)C)[C@H]3CC4; InChI: InChI=1/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h10,13-16H,2-9H2,1H3/t13-,14+,15+,16-,18-/m0/s1.

The Estr-4-ene-3,17-dione has many suppliers, such as Emerald-Shanghai Incorporation, Techwin Bio.& Pharm.Technology Limited, Xianju Green Leaf Pharmaceutical Factory and Yangzhou Lianhuan Pharmaceutical Co., Ltd..

Use and Manufacturing

【Usage】
Norethindrone intermediate

Biomedical Effects and Toxicity

【Therapeutic Uses】
Norethindrone intermediate

Supplier Location

Top Suppliers

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Raw materials

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