- Cas NO.:144598-75-4
- Molecular Formula:C23H27FN4O3
- Melting Point:158-160°C
- Boiling Point:612.3 °C at 760 mmHg
- Refractive index:1.692
- Flash Point:324.1 °C
- Appearance:off white to light orange coloured solid
It is indicated for the acute and maintenance treatment of schizophrenia. The drug significantly reduces side-effects present in other anti-psychotic drugs formerly used to treat schizophrenia and bipolar disorder. In short-term studies paliperidone has been shown to be effective, demonstrating improvements in symptom scores, compared with placebo.
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It is used for the treatment of schizophrenia and schizoaffective disorder. In a 2013 study in a comparison of 15 antipsychotic drugs in effectiveness in treating schizophrenic symptoms, paliperidone was ranked fifth and demonstrated standard-high effectiveness. 10-14% more effective than haloperidol, quetiapine, and aripiprazole, 11% less effective than risperidone (4th), and 43% less effective than clozapine (1st).