|Organism||Test Type||Route||Reported Dose (Normalized Dose)||Effect||Source|
|mammal (species unspecified)||LD50||subcutaneous||296mg/kg (296mg/kg)||?||"Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 25, 1982.|
|mouse||LD50||intraperitoneal||8500ug/kg (8.5mg/kg)||PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE
BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)
LUNGS, THORAX, OR RESPIRATION: CYANOSIS
|Biochemical Pharmacology. Vol. 12, Pg. 885, 1963.|
|mouse||LD50||oral||25mg/kg (25mg/kg)||BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
SKIN AND APPENDAGES (SKIN): HAIR: OTHER
|National Technical Information Service. Vol. OTS0571885,|
|mouse||LD50||subcutaneous||93800ug/kg (93.8mg/kg)||?||Zeitschrift fuer die Gesamte Innere Medizin und Ihre Grenzgebiete. Vol. 2, Pg. 333, 1947.|
|rat||LD50||intraperitoneal||30mg/kg (30mg/kg)||?||Pharmaceutical Bulletin. Vol. 3, Pg. 337, 1955.|
|rat||LD50||intravenous||25mg/kg (25mg/kg)||?||Federation Proceedings, Federation of American Societies for Experimental Biology. Vol. 8, Pg. 348, 1949.|
|rat||LD50||oral||130mg/kg (130mg/kg)||?||Federation Proceedings, Federation of American Societies for Experimental Biology. Vol. 8, Pg. 348, 1949.|
|rat||LD50||unreported||5600ug/kg (5.6mg/kg)||BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD||Russian Pharmacology and Toxicology Vol. 41, Pg. 146, 1978.|
Safety Information of?Quinone (CAS NO.106-51-4):
Hazard Codes:T ,N ,Xn , F
23/25:Toxic by inhalation and if swallowed?
36/37/38:Irritating to eyes, respiratory system and skin?
50:Very Toxic to aquatic organisms?
20/21/22:Harmful by inhalation, in contact with skin and if swallowed
26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice??
28:After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer)
45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)?
61:Avoid release to the environment. Refer to special instructions safety data sheet?
23:Do not breathe gas/fumes/vapor/spray (appropriate wording to be specified by the manufacturer)
16:Keep away from sources of ignition - No smoking???
RIDADR:UN 2587 6.1/PG 2
Poison by ingestion, subcutaneous, intraperitoneal, and intravenous routes. Questionable carcinogen with experimental tumorigenic data by skin contact. Human mutation data reported. Quinone has a characteristic, irritating odor. Causes severe damage to the skin and mucous membranes by contact with it in the solid state, in solution, or in the form of condensed vapors. Locally, it causes discoloration, severe irritation, erythema, swelling, and the formation of papules and vesicles, whereas prolonged contact may lead to necrosis. When the eyes become involved, it causes dangerous disturbances of vision. The moist material self-heats and decomposes exothermically above 60°C. When heated to decomposition it emits acrid smoke and fumes.