Epichlorohydrin (cas 106-89-8) Molecular Structure

CAS No. 106-89-8 (Epichlorohydrin )

Molecular Formula: C3H5ClOMolecular Weight: 92.52

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    DetailDesc: epichlorohydrin Name: Epichlorohydrin Synonyms:1-Chloro-2,3-epoxypropane;2-(Chloromethyl)oxirane; 3-Chloro-1,2-epoxypropane CAS NO: 106-89-8 EINECS: 203-439-8 Molecular Structure: Molecular Formula: C3H5ClO Molecular Weight: 92.52 Appearance: colorless oily liquid with chloroform odor stimulus Density: 1.183 Melting point: -57 ºC Bo...

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References of Epichlorohydrin cas 106-89-8

} Toxicity

1. ???

skn-rbt 10?mg/24H open

??? JIHTAB ?? Journal of Industrial Hygiene and Toxicology. 30 (1948),63.
2. ???

eye-rbt 100?mg/24H MOD

??? 85JCAE ?? Prehled Prumyslove Toxikologie; Organicke Latky Marhold, J.,Prague, Czechoslovakia.:?Avicenum,1986,769.
3. ???

dni-hmn:hla 2700 μmol/L

??? MUREAV ?? Mutation Research. 92 (1982),427.
4. ???

sce-hmn:lym 10?nmol/L

??? CARYAB ?? Caryologia. 34 (1981),261.
5. ???

spm-mus-ihl 5?mg/m3

??? MUREAV ?? Mutation Research. 85 (1981),287.
6. ???

orl-mus TDLo:1200?mg/kg (female 6-15D post):TER

??? JTEHD6 ?? Journal of Toxicology and Environmental Health. 9 (1982),87.
7. ???

ihl-rat TCLo:50?ppm/6H (male 50D pre):REP

??? TXAPA9 ?? Toxicology and Applied Pharmacology. 68 (1983),415.
8. ???

orl-rat TDLo:60?g/kg/81W-I:CAR

??? GANNA2 ?? Gann. Japanese Journal of Cancer Research. 71 (1980),922.
9. ???

ihl-rat TCLo:100?ppm/6H/30D-C:CAR

??? JJIND8 ?? JNCI, Journal of the National Cancer Institute. 65 (1980),751.
10. ???

ipr-mus TDLo:2400?mg/kg/8W-I:NEO

??? TXAPA9 ?? Toxicology and Applied Pharmacology. 82 (1986),19.

?

Safety

Confirmed carcinogen with experimental carcinogenic data. Poison by ingestion, skin contact, intravenous, and intraperitoneal routes. Moderately toxic by inhalation. An experimental teratogen. Other experimental reproductive effects. Human systemic effects by inhalation: respiratory, nose, and eyes. Human mutation data reported. A skin and eye irritant. A sensitizer. Flammable liquid when exposed to heat or flame. Explosive reaction with aniline. Reaction with trichloroethylene forms the explosive dichloroacetylene. Ignition on contact with potassium tert-butoxide. Violent reaction with sulfuric acid or isopropylamine. Exothermic polymerization on contact with strong acids, caustic alkalies, aluminum, aluminum chloride, iron(III) chloride, or zinc. When heated to decomposition it emits toxic fumes of Cl?.
Hazard Codes?: T?Toxic
Risk Statements? :45-10-23/24/25-34-43?
R45:May cause cancer.?
R10:Flammable.?
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed.?
R43:May cause sensitization by skin contact.
Safety Statements? :53-45?
S53:Avoid exposure - obtain special instructions before use.?
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR:? UN 2023 6.1/PG 2
WGK Germany:? 3