Hydroquinone (cas 123-31-9) Molecular Structure

CAS No. 123-31-9 (Hydroquinone )

Molecular Formula: C6H6O2Molecular Weight: 110.11

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References of Hydroquinone cas 123-31-9

} Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LD50 oral 50mg/kg (50mg/kg) ? National Technical Information Service. Vol. OTS0555537,
cat LDLo subcutaneous 50mg/kg (50mg/kg) BEHAVIORAL: TREMOR

BLOOD: METHEMOGLOBINEMIA-CARBOXYHEMOGLOBIN

VASCULAR: REGIONAL OR GENERAL ARTERIOLAR OR VENOUS DILATION
Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 72, Pg. 241, 1913.
dog LD50 oral 200mg/kg (200mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: EXCITEMENT

GASTROINTESTINAL: NAUSEA OR VOMITING
Federation Proceedings, Federation of American Societies for Experimental Biology. Vol. 8, Pg. 348, 1949.
dog LDLo intravenous 80mg/kg (80mg/kg) ? "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 1, Pg. 162, 1955.
dog LDLo subcutaneous 100mg/kg (100mg/kg) ? Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 183, Pg. 319, 1936.
frog LDLo parenteral 190mg/kg (190mg/kg) PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

CARDIAC: OTHER CHANGES
Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 166, Pg. 437, 1932.
frog LDLo subcutaneous 190mg/kg (190mg/kg) ? "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 1, Pg. 160, 1955.
guinea pig LD50 oral 550mg/kg (550mg/kg) BEHAVIORAL: TREMOR

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: EXCITEMENT
Federation Proceedings, Federation of American Societies for Experimental Biology. Vol. 8, Pg. 348, 1949.
guinea pig LDLo intraperitoneal 200mg/kg (200mg/kg) ? "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 1, Pg. 162, 1955.
guinea pig LDLo subcutaneous 300mg/kg (300mg/kg) ? "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 1, Pg. 162, 1955.
human LDLo oral 29mg/kg (29mg/kg) ? "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 321, 1969.
human TDLo oral 170mg/kg (170mg/kg) BEHAVIORAL: COMA

CARDIAC: PULSE RATE INCREASE WITHOUT FALL IN BP

LUNGS, THORAX, OR RESPIRATION: CYANOSIS
Annales de Medecine Legale. Criminologie, Police Scientifique et Toxicologie. Vol. 7, Pg. 79, 1927.
mammal (species unspecified) LD50 oral 480mg/kg (480mg/kg) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)

LUNGS, THORAX, OR RESPIRATION: DYSPNEA

BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)
Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. Vol. 15, Pg. 136, 1979.
mammal (species unspecified) LD50 skin 5970mg/kg (5970mg/kg) ? Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 45(10), Pg. 16, 1980.
mouse LD50 intraperitoneal 100mg/kg (100mg/kg) ? National Technical Information Service. Vol. AD414-344,
mouse LD50 oral 245mg/kg (245mg/kg) ? Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 38(8), Pg. 6, 1973.
mouse LD50 subcutaneous 182mg/kg (182mg/kg) ? Zeitschrift fuer die Gesamte Innere Medizin und Ihre Grenzgebiete. Vol. 2, Pg. 333, 1947.
mouse LD50 unreported 150mg/kg (150mg/kg) ? British Journal of Cancer. Vol. 6, Pg. 160, 1952.
pigeon LD50 oral 300mg/kg (300mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

GASTROINTESTINAL: NAUSEA OR VOMITING

BEHAVIORAL: EXCITEMENT
Federation Proceedings, Federation of American Societies for Experimental Biology. Vol. 8, Pg. 348, 1949.
rabbit LD50 intraperitoneal 125mg/kg (125mg/kg) ? Ecotoxicology and Environmental Safety. Vol. 19, Pg. 327, 1990.
rabbit LD50 oral 200mg/kg (200mg/kg) ? International Polymer Science and Technology. Vol. 3, Pg. 93, 1976.
rabbit LDLo intravenous 100mg/kg (100mg/kg) ? Agressologie. Revue Internationale de Physio-Biologie et de Pharmacologie Appliquees aux Effets de l'Agression. Vol. 3, Pg. 311, 1962.
rat LD50 intraperitoneal 170mg/kg (170mg/kg) ? Ecotoxicology and Environmental Safety. Vol. 19, Pg. 327, 1990.
?
rat LD50 intravenous 115mg/kg (115mg/kg) BEHAVIORAL: TREMOR

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: EXCITEMENT
Federation Proceedings, Federation of American Societies for Experimental Biology. Vol. 8, Pg. 348, 1949.
rat LD50 oral 302mg/kg (302mg/kg) ? National Technical Information Service. Vol. OTS0555537,
rat LD50 unreported 720mg/kg (720mg/kg) ? Gigiena Truda i Professional'naya Patologiya v Estonskoi SSR. Labor Hygiene and Occupational Pathology in the Estonian SSR. Vol. 8, Pg. 145, 1972.
rat LDLo subcutaneous 300mg/kg (300mg/kg) ? "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 1, Pg. 162, 1955.

Safety

Safety Information of Hydroquinone (CAS NO.123-31-9):
Hazard Codes: XnHarmful,NDangerous
Risk Statements: 22-40-41-43-50-68??
R22:Harmful if swallowed.?
R40:Limited evidence of a carcinogenic effect.?
R41:Risk of serious damage to the eyes.?
R50:Very toxic to aquatic organisms.?
R68:Possible risk of irreversible effects.
Safety Statements: 26-36/37/39-61
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.?
S61:Avoid release to the environment. Refer to special instructions / safety data sheets.
RIDADR: 2662
WGK Germany: 3
RTECS: MX3500000
HazardClass: 9
PackingGroup: III