Erythromycin ethylsuccinate (cas 1264-62-6) Molecular Structure

CAS No. 1264-62-6 (Erythromycin ethylsuccinate )

Molecular Formula: C43H75NO16Molecular Weight: 862.0527

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References of Erythromycin ethylsuccinate cas 1264-62-6

} Toxicity

CHEMICAL IDENTIFICATION

RTECS NUMBER :
WM9800000
CHEMICAL NAME :
Succinic acid, monoethyl ester, monoester with erythromycin
CAS REGISTRY NUMBER :
1264-62-6
BEILSTEIN REFERENCE NO. :
0077638
LAST UPDATED :
199612
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C43-H75-N-O16
MOLECULAR WEIGHT :
862.19
WISWESSER LINE NOTATION :
T-14-VO GVTJ C2 DQ D1 EQ F1 H1 JQ J1 L1 N1 KO- BT6OTJ CQ DN1&1 F1& MO- FT6OTJ B1 CQ DO1 D1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Human - child
DOSE/DURATION :
420 mg/kg/7D-I
TOXIC EFFECTS :
Gastrointestinal - nausea or vomiting Liver - other changes
REFERENCE :
CMAJAX Canadian Medical Association Journal. (Canadian Medical Assoc., POB 8650, Ottawa, ON K1G 0G8, Canada) V.1- 1911- Volume(issue)/page/year: 129,411,1983
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Human - man
DOSE/DURATION :
5714 ug/kg
TOXIC EFFECTS :
Behavioral - ataxia
REFERENCE :
AJEMEN American Journal of Emergency Medicine. (WB Saunders, Philadelphia, PA) V.1- 1983- Volume(issue)/page/year: 10,616,1992
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
4167 mg/kg
TOXIC EFFECTS :
Gastrointestinal - hypermotility, diarrhea
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 9,445,1966
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>10 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,126,1982 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M0949 No. of Facilities: 113 (estimated) No. of Industries: 2 No. of Occupations: 7 No. of Employees: 3065 (estimated) No. of Female Employees: 1433 (estimated)

Safety

Safety Information of Erythromycin ethylsuccinate (CAS NO.1264-62-6):
Hazard Codes: XnHarmful,XiIrritant
Risk Statements: 42/43-36/37/38??
Safety Statements: 36-26
WGK Germany: 2
RTECS: WM9800000
Hazardous Substances Data: 1264-62-6(Hazardous Substances Data)??