Products
  • Products
  • Cas lib
  • Buy offers
  • Encyclopedia
  • Msds lib
  • Synthesis
  • Reach Info
  • Suppliers
Home> CAS DataBase Listed 1 > CAS 17902-23-7
Identification of 17902-23-7
  • Name:
  • Ftorafur (Related Reference)
  • EINECS:
  • 241-846-2
  • Synonyms:
  • 5-Fluoro-1-(tetrahydro-2-furyl)uracil; 5-Fluoro-1-(tetrahydro-2-furfuryl)uracil; Tegafur; 5-fluoro-1-(tetrahydrofuran-2-yl)uracil; 1-Naphthol-3,8-Disulfonic Acid; Epsilone Acid; 5-fluoro-1-oxolan-2-yl-pyrimidine-2,4-dione
  • InChI:
  • InChI=1S/C8H9FN2O3/c9-5-4-11(6-2-1-3-14-6)8(13)10-7(5)12/h4,6H,1-3H2,(H,10,12,13)
  • This structure is also available as a 2d Mol file
Safety Data of 17902-23-7 Properties of 17902-23-7
  • Appearance:
  • White Crystalline Powder
  • Molecular Weight:
  • 200.167063
  • Density:
  • 1.45 g/cm3
  • Boiling Point:
  • oCat760mmHg
  • Melting Point:
  • 168-171℃
  • Flash Point:
  • oC
  • Storage Temperature:
  • 2-8°C
  • Refractive index:
  • 1.557
  • Solubility:
  • Soluble in hot water
  • Stability:
  • Stable under normal temperatures and pressures.
  • Usage:
  • Used as an antineoplastic

  • More>>

CAS No. 17902-23-7 (Ftorafur )

  • CAS No:17902-23-7
  • Molecular Weight: 200.167063
  • Molecular Formula: C8H9FN2O3
Properties Safety and Handling MSDS NMR Spectrum Synthesis Route Precursor and Product
Top quality Tegafur cas 17902-23-7
  • FOB Price:1 USD/Gram 
  • Cas No:17902-23-7 
  • Min.Order:10/Gram 
  • Purity:99% 
  • Supply Ability:5 Quarter/Metric Ton 
  • Formula:C8H9FN2O3 
  • Payment:T/T,Western Union,MoneyGram,bitcoin, 
  • Updatetime:Jun 15 2018 
Nanjing Bangnuo Biotechnology Co., Ltd 1YR Main Products
Rich stock in raw material is up to ten thousand kinds, including steroid series, peptide & sarms series,medical material, chemical material and ect
Contact Supplier
Ftorafur
  • FOB Price:1 USD/Kilogram 
  • Cas No:17902-23-7 
  • Min.Order:1/Kilogram 
  • Purity:95%, 99% 
  • Supply Ability:20 Year/Metric Ton 
  • Formula:C8H9FN2O3 
  • Payment:T/T, L/C 
  • Updatetime:Jun 15 2018 
Tegafur
  • FOB Price:  
  • Cas No:17902-23-7 
  • Min.Order: 
  • Purity:99%min 
  • Supply Ability:Stable stock  
  • Formula:C8H9FN2O3 
  • Payment:T/T L/C D/P, 
  • Updatetime:Jun 15 2018 
Ftorafur white powder
  • FOB Price:1 USD/Gram 
  • Cas No:17902-23-7 
  • Min.Order:1/Gram 
  • Purity:99% 
  • Supply Ability:100 Day/Kilogram 
  • Formula:C8H9FN2O3 
  • Payment:T/T,Western Union,MoneyGram, 
  • Updatetime:Jun 14 2018 
Hubei XinRunde Chemical Co., Ltd 2YRS Main Products
Pharmaceutical Intermediate; Pharmaceutical Raw Materials; Raw Steroid Powders; Raw Hormone Powders; etc
Contact Supplier
Tegafur
  • FOB Price:  
  • Cas No:17902-23-7 
  • Min.Order: 
  • Purity:99% 
  • Supply Ability:  
  • Formula:C8H9FN2O3 
  • Payment: 
  • Updatetime:Jun 07 2018 
AOPHARM 7YRS Main Products
Pharmaceutical Intermediate, API, Botanical Extract
Contact Supplier
Tegafur
  • FOB Price:  
  • Cas No:17902-23-7 
  • Min.Order: 
  • Purity:97% 
  • Supply Ability:  
  • Formula:C8H9FN2O3 
  • Payment: 
  • Updatetime:May 23 2018 
Tegafur
  • FOB Price:100 USD/Kilogram 
  • Cas No:17902-23-7 
  • Min.Order:1/Kilogram 
  • Purity:99% 
  • Supply Ability:100 Month/Kilogram 
  • Formula:C8H9FN2O3 
  • Payment:T/T 
  • Updatetime:Mar 13 2018 
Jinlan Pharm-Drugs Technology Co., Limited 5YRS Main Products
Veterinary products,Nutrition products,Agrochemicals,Active pharmaceutical Ingredients,Custom systhesis,Contract manufacturing
Contact Supplier
Tegafur
  • FOB Price:  
  • Cas No:17902-23-7 
  • Min.Order: 
  • Purity:99%min 
  • Supply Ability:  
  • Formula:C8H9FN2O3 
  • Payment: 
  • Updatetime:Sep 06 2017 
Hangzhou J&H Chemical Co., Ltd 4YRS Main Products
3,5-Dibromoanisole,5-Fluoro-2-nitroanisole,Doxorubicin hydrochloride,Diethyl 4-oxoheptanedioate,1,5-Diphenylpenta-1,4-dien-3-one,3,5-Dimethoxy-4-hydroxycinnamic acid
Contact Supplier
Ftorafur
  • FOB Price:  
  • Cas No:17902-23-7 
  • Min.Order: 
  • Supply Ability:  
  • Formula:C8H9FN2O3 
  • Payment: 
  • Updatetime:Feb 24 2018 
Nanjing Bangnuo Biotechnology Co., Ltd. Main Products
Testosterone, Boldenone, Nandrolone, Trenbolone, DECA, Anavar, GHRP-6, MT-2, HGH176-191, SARMs, GBL, Phenacetin, BB, BA etc.
Contact Supplier
Tegafur
  • FOB Price:  
  • Cas No:17902-23-7 
  • Min.Order: 
  • Purity:99% 
  • Supply Ability:80  
  • Formula:C8H9FN2O3 
  • Payment:L/C,T/T,Western Union, 
  • Updatetime:Feb 06 2018 
MOSINTER GROUP LIMITED Main Products
Additives for Gasoline and diesel, Pharmaceutical Products, Fire retardant products
Contact Supplier
Ftorafur
  • FOB Price:750 USD/Kilogram 
  • Cas No:17902-23-7 
  • Min.Order:1/Kilogram 
  • Purity:99% 
  • Supply Ability:1000 Quarter/Kilogram 
  • Formula:C8H9FN2O3 
  • Payment:L/C,T/T,Western Union, 
  • Updatetime:Jun 14 2017 
Jinan Jianfeng Chemical Co., Ltd Main Products
pharmaceutical chemicals and intermediates. including Anticancer,Antifungal,Anesthesia,,such as Bortezomib, apixaban, lidocaine, nifuratel, pregablin, Propofol,Sorafenib tosylate,
Contact Supplier
Tegafur 17902-23-7
  • FOB Price:100 USD/Gram 
  • Cas No:17902-23-7 
  • Min.Order: 
  • Purity:99% 
  • Supply Ability:mass stock  
  • Formula:C8H9FN2O3 
  • Payment:L/C,T/T,Western Union,MoneyGran, 
  • Updatetime:Feb 04 2017 
Shenzhen Simeiquan Biotechnology Co.Ltd Main Products
food additives ,flavor and fragrance,Pharmaceutical intermediates.steroid.special for anbolic steroid hormone powder Muscle Building Steroids,Oral Anabolic Steroids,Injectable Anabolic Steroids
Contact Supplier
Hot sell High Qualit Tegafur (CAS 17902-23-7 )
  • FOB Price:1 USD/Kilogram 
  • Cas No:17902-23-7 
  • Min.Order:10/Kilogram 
  • Purity:99% 
  • Supply Ability:50000 Year/Kilogram 
  • Formula:C8H9FN2O3 
  • Payment:L/C,D/A,D/P,T/T,Western Union, 
  • Updatetime:Sep 29 2016 
Wuhan Dahua Weiye Pharmaceutical Co.,Ltd Main Products
Pharmaceutical, pharmaceutical intermediat,hormone powders
Contact Supplier
Tegafur
  • FOB Price:  
  • Cas No:17902-23-7 
  • Min.Order: 
  • Supply Ability:  
  • Formula:C8H9FN2O3 
  • Payment: 
  • Updatetime:Sep 22 2016 
Shanghai Hope Chem Co., Ltd. Main Products
Shanghai Hope Chem Co., Ltd. was founded in 2014 with registered capital of RMB 2 million Yuan.
Contact Supplier
Ftorafur
  • FOB Price:1 USD/Gram 
  • Cas No:17902-23-7 
  • Min.Order:10/Gram 
  • Purity:99.9% 
  • Supply Ability:10 Month/Metric Ton 
  • Formula:C8H9FN2O3 
  • Payment:T/T,Western Union,MoneyGram, 
  • Updatetime:Sep 21 2016 
Hubei Yuancheng Saichuang Technology Co., Ltd Main Products
Anabolic Steroid Hormone Powder, Muscle Building Steroids, Oral Anabolic Steroids, Injectable Anabolic Steroids, Pharmaceutical Raw Materials, Food Additives, Flavor&,Fragrance
Contact Supplier
5-Fluoro-1-(tetrahydro-2-furyl)uracil
  • FOB Price:  
  • Cas No:17902-23-7 
  • Min.Order:1/Kilogram 
  • Purity:99 
  • Supply Ability:100 Year/Metric Ton 
  • Formula:C8H9FN2O3 
  • Payment:LC 
  • Updatetime:Jul 28 2016 
Jinan Haohua Industry Co., Ltd. Main Products
Chlorodimethylsilane;1,1,3,3-tetramethyldisiloxane
Contact Supplier
Tegafur
  • FOB Price:10 USD/Kilogram 
  • Cas No:17902-23-7 
  • Min.Order:10/Gram 
  • Purity:99% 
  • Supply Ability:20 Month/Metric Ton 
  • Formula:C8H9FN2O3 
  • Payment:T/T,L/C,Western union,Moneygram 
  • Updatetime:Jul 12 2016 
Wuhan Senwayer Century chemical Co.,Ltd Main Products
API,intermediate, Agrochemical,Amino Acids
Contact Supplier
Tegafur
  • FOB Price:  
  • Cas No:17902-23-7 
  • Min.Order:1/Gram 
  • Purity:98.00% 
  • Supply Ability:  
  • Formula:C8H9FN2O3 
  • Payment:T/T 
  • Updatetime:May 13 2016 
Tegafur
  • FOB Price:1 USD/Kilogram 
  • Cas No:17902-23-7 
  • Min.Order:1/Kilogram 
  • Purity:98% 
  • Supply Ability:1 Year/Kilogram 
  • Formula:C8H9FN2O3 
  • Payment:T/T, 
  • Updatetime:Nov 20 2015 
Suzhou Yacoo Chemical Reagent Corporation Main Products
Biobuffer Electronic Chemical Pharmaceutical Intermediate Diagnostic Reagent
Contact Supplier
Ftorafur
  • FOB Price:  
  • Cas No:17902-23-7 
  • Min.Order: 
  • Supply Ability:  
  • Formula:C8H9FN2O3 
  • Payment: 
  • Updatetime:Nov 02 2015 
Zhejiang Haiqiang Chemical Co.,Ltd. Main Products
API Intermediate Plant extracts Pigments and dyes Food and feed additives Reagent Customization synthesisOther products
Contact Supplier
Precursor and Product
References of Ftorafur cas 17902-23-7

Toxicity

CHEMICAL IDENTIFICATION

RTECS NUMBER :
YR0450000
CHEMICAL NAME :
Uracil, 5-fluoro-1-(tetrahydro-2-furyl)-
CAS REGISTRY NUMBER :
17902-23-7
BEILSTEIN REFERENCE NO. :
0525766
LAST UPDATED :
199706
DATA ITEMS CITED :
43
MOLECULAR FORMULA :
C8-H9-F-N2-O3
MOLECULAR WEIGHT :
200.19
WISWESSER LINE NOTATION :
T6NVMVJ EF A- BT5OTJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Human - man
DOSE/DURATION :
197 mg/kg/23D-I
TOXIC EFFECTS :
Brain and Coverings - encephalitis Behavioral - muscle contraction or spasticity Behavioral - antipsychotic
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Human
DOSE/DURATION :
640 mg/kg/8D
TOXIC EFFECTS :
Behavioral - hallucinations, distorted perceptions Vascular - BP lowering not characterized in autonomic section Gastrointestinal - nausea or vomiting
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Human
DOSE/DURATION :
23 mg/kg
TOXIC EFFECTS :
Behavioral - hallucinations, distorted perceptions
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
930 mg/kg
TOXIC EFFECTS :
Gastrointestinal - ulceration or bleeding from stomach Nutritional and Gross Metabolic - weight loss or decreased weight gain
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
700 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - other changes
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
600 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Gastrointestinal - ulceration or bleeding from stomach Nutritional and Gross Metabolic - weight loss or decreased weight gain
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
685 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
775 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
493 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
760 mg/kg
TOXIC EFFECTS :
Gastrointestinal - hypermotility, diarrhea Gastrointestinal - nausea or vomiting
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
800 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
34 mg/kg
TOXIC EFFECTS :
Behavioral - tremor Vascular - other changes Gastrointestinal - nausea or vomiting
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - cat
DOSE/DURATION :
36 mg/kg
TOXIC EFFECTS :
Behavioral - tremor Gastrointestinal - nausea or vomiting
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
44 mg/kg
TOXIC EFFECTS :
Vascular - other changes
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
40 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
17640 mg/kg/12W-I
TOXIC EFFECTS :
Endocrine - changes in spleen weight Blood - changes in bone marrow (not otherwise specified) Related to Chronic Data - changes in testicular weight
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
14040 mg/kg/13W-I
TOXIC EFFECTS :
Endocrine - changes in thymus weight Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Related to Chronic Data - changes in testicular weight
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
700 mg/kg/40W-I
TOXIC EFFECTS :
Cardiac - changes in heart weight Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Nutritional and Gross Metabolic - weight loss or decreased weight gain
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
7 gm/kg/5W-I
TOXIC EFFECTS :
Blood - normocytic anemia Blood - changes in bone marrow (not otherwise specified) Blood - changes in leukocyte (WBC) count
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
20160 mg/kg/24W-I
TOXIC EFFECTS :
Blood - changes in bone marrow (not otherwise specified) Blood - changes in leukocyte (WBC) count Related to Chronic Data - changes in testicular weight
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
880 mg/kg/80D-I
TOXIC EFFECTS :
Endocrine - changes in adrenal weight Nutritional and Gross Metabolic - weight loss or decreased weight gain
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1170 mg/kg/9D-I
TOXIC EFFECTS :
Related to Chronic Data - death
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
1365 mg/kg/13W-I
TOXIC EFFECTS :
Behavioral - food intake (animal) Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
1820 mg/kg/26W-I
TOXIC EFFECTS :
Brain and Coverings - other degenerative changes Related to Chronic Data - death
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
350 mg/kg/5W-I
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - chronic pulmonary edema Liver - other changes Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis)
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Human - man
DOSE/DURATION :
11046 mg/kg/4.7Y-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Gastrointestinal - tumors
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
810 mg/kg
SEX/DURATION :
female 17-22 day(s) after conception lactating female 21 day(s) post-birth
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - urogenital system Reproductive - Effects on Newborn - behavioral
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
550 mg/kg
SEX/DURATION :
female 7-17 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - extra-embryonic structures (e.g., placenta, umbilical cord)
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intravenous
DOSE :
420 mg/kg
SEX/DURATION :
female 7-13 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Specific Developmental Abnormalities - musculoskeletal system
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intravenous
DOSE :
630 mg/kg
SEX/DURATION :
female 7-13 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intravenous
DOSE :
210 mg/kg
SEX/DURATION :
female 6-12 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Effects on Embryo or Fetus - fetal death Reproductive - Specific Developmental Abnormalities - musculoskeletal system
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intravenous
DOSE :
630 mg/kg
SEX/DURATION :
female 6-12 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)
TYPE OF TEST :
Specific locus test
TYPE OF TEST :
Micronucleus test
TYPE OF TEST :
Unscheduled DNA synthesis
TYPE OF TEST :
Unscheduled DNA synthesis
TYPE OF TEST :
Mutation test systems - not otherwise specified
TYPE OF TEST :
Mutation test systems - not otherwise specified
TYPE OF TEST :
Cytogenetic analysis

MUTATION DATA

TYPE OF TEST :
Cytogenetic analysis
TEST SYSTEM :
Rodent - hamster Fibroblast
DOSE/DURATION :
100 mg/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 88,241,1981