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Home> CAS DataBase Listed 1 > CAS 19387-91-8
Identification of 19387-91-8
  • Name:
  • 1H-Imidazole,1-[2-(ethylsulfonyl)ethyl]-2-methyl-5-nitro- (Related Reference)
  • EINECS:
  • 243-014-4
  • Synonyms:
  • Imidazole,1-[2-(ethylsulfonyl)ethyl]-2-methyl-5-nitro- (8CI); 1-(Ethylsulfonylethyl)-2-methyl-5-nitroimidazole; Bioshik; CP 12574; Fasigin; Fasigyn; Glongyn; Pletil; Simplotan; Sorquetan; Tini 300;
  • InChI:
  • InChI=1S/C8H13N3O4S/c1-3-16(14,15)5-4-10-7(2)9-6-8(10)11(12)13/h6H,3-5H2,1-2H3
  • This structure is also available as a 2d Mol file
Safety Data of 19387-91-8 Properties of 19387-91-8
  • Appearance:
  • almost white or pale yellow, crystalline powder
  • Molecular Weight:
  • 247.27152
  • Density:
  • 1.43 g/cm3
  • Boiling Point:
  • 528.4oC at 760 mmHg
  • Melting Point:
  • 125oCto 128oC
  • Flash Point:
  • 273.4oC
  • Storage Temperature:
  • Keep tightly closed.
  • Refractive index:
  • 1.599
  • Solubility:
  • practically insoluble in water, soluble in acetone and in methylene chloride, sparingly soluble in methanol.
  • Stability:
  • Stable. Incompatible with strong oxidizing agents.
  • Usage:
  • Used to treat protozoal infections, such as amebiasis, giardiasis, and trichomoniasis.

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CAS No. 19387-91-8 (1H-Imidazole,1-[2-(ethylsulfonyl)ethyl]-2-methyl-5-nitro- )

  • CAS No:19387-91-8
  • Molecular Weight: 247.27152
  • Molecular Formula: C8H13N3O4S
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References of 1H-Imidazole,1-[2-(ethylsulfonyl)ethyl]-2-methyl-5-nitro- cas 19387-91-8

Toxicity

1. ???

mmo-sat 50?μg/plate

??? MUREAV ?? Mutation Research. 77 (1980),301.
2. ???

mnt-mus-ipr 50?mg/kg

??? AIVMBU ?? Archivos de Investigacion Medica. 15 (1984),311.
3. ???

orl-rat LD50:2710?mg/kg

??? IYKEDH ?? Iyakuhin Kenkyu. Study of Medical Supplies. 11 (1980),811.
4. ???

ipr-rat LD50:2720?mg/kg

??? IYKEDH ?? Iyakuhin Kenkyu. Study of Medical Supplies. 11 (1980),811.
5. ???

scu-rat LD50:3000?mg/kg

??? IYKEDH ?? Iyakuhin Kenkyu. Study of Medical Supplies. 11 (1980),811.
6. ???

orl-mus LD50:3200?mg/kg

??? JMCMAR ?? Journal of Medicinal Chemistry. 21 (1978),781.
7. ???

ipr-mus LD50:2730?mg/kg

??? IYKEDH ?? Iyakuhin Kenkyu. Study of Medical Supplies. 11 (1980),811.
8. ???

scu-mus LD50:3940?mg/kg

??? IYKEDH ?? Iyakuhin Kenkyu. Study of Medical Supplies. 11 (1980),811.

Safety

Moderately toxic by ingestion, intraperitoneal, and subcutaneous routes. An experimental teratogen. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits very toxic fumes of NOx and SOx.
Hazard Codes:Harmful Xn
Risk Statements: 20/21/22-40?
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.?
R40:Limited evidence of a carcinogenic effect.
Safety Statements 26-36?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S36:Wear suitable protective clothing.
WGK Germany: 3
RTECS: NI6255000

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