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Home> CAS DataBase Listed 4 > CAS 434-05-9
Identification of 434-05-9
  • Name:
  • Androst-1-en-3-one,17-(acetyloxy)-1-methyl-, (5a,17b)- (Related Reference)
  • EINECS:
  • 207-097-0
  • Synonyms:
  • 5a-Androst-1-en-3-one, 17b-hydroxy-1-methyl-, acetate(6CI,8CI); 1-Methyl-17b-hydroxy-5a-androst-1-en-3-oneacetate; 1-Methyl-17b-hydroxy-5a-androst-1-en-3-one-17b-acetate; 1-Methyl-5a-androst-1-en-17b-ol-3-one acetate; 17b-Hydroxy-1-methyl-5a-androst-1-en-3-one acetate; Methenolone 17-acetate; Methenolone acetate; NSC 74226; Nibal; Primobolan; Primobolan Tablets; Primobolone; Primonabol; SH 567; SH567a; SQ 16496
  • InChI:
  • InChI=1/C22H32O3/c1-13-11-16(24)12-15-5-6-17-18-7-8-20(25-14(2)23)21(18,3)10-9-19(17)22(13,15)4/h11,15,17-20H,5-10,12H2,1-4H3/t15-,17-,18-,19-,20-,21-,22-/m0/s1
  • This structure is also available as a 2d Mol file
Safety Data of 434-05-9
Properties of 434-05-9
  • Molecular Weight:
  • 344.54
  • Density:
  • 1.1g/cm3
  • Boiling Point:
  • 441.2°Cat760mmHg
  • Flash Point:
  • 189.9°C
  • Refractive index:
  • 1.536
  • More>>

CAS No. 434-05-9 (Androst-1-en-3-one,17-(acetyloxy)-1-methyl-, (5a,17b)- )

  • CAS No:434-05-9
  • Molecular Weight: 344.54
  • Molecular Formula: C22H32O3
Properties Safety and Handling MSDS NMR Spectrum Synthesis Route Precursor and Product
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Precursor and Product
precursor:
1099-80-5
product :
References of Androst-1-en-3-one,17-(acetyloxy)-1-methyl-, (5a,17b)- cas 434-05-9

Toxicity

CHEMICAL IDENTIFICATION

RTECS NUMBER :
BV8408500
CHEMICAL NAME :
5-alpha-Androst-1-en-3-one, 17-beta-hydroxy-1-methyl-, acetate
CAS REGISTRY NUMBER :
434-05-9
LAST UPDATED :
199309
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C22-H32-O3
MOLECULAR WEIGHT :
344.54
WISWESSER LINE NOTATION :
L E5 B666 OV LUTJ A1 E1 FOV1 K1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
4 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,835,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
4 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,835,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,835,1982 ** REPRODUCTIVE DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
200 mg/kg
SEX/DURATION :
male 10 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Paternal Effects - prostate, seminal vesicle, Cowper's gland, accessory glands
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 14,330,1964
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
60 mg/kg
SEX/DURATION :
female 17-20 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - urogenital system
REFERENCE :
AVBIB9 Advances in the Biosciences. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1967- Volume(issue)/page/year: 13,71,1974

Safety

Moderately toxic by ingestion and intraperitoneal routes. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits acrid smoke and irritating fumes.

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