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Home> CAS DataBase Listed 6 > CAS 633-65-8
Identification of 633-65-8
  • Name:
  • Berberine hydrochloride (Related Reference)
  • EINECS:
  • 211-195-9
  • Synonyms:
  • NSC 646666; Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium,5,6-dihydro-9,10-dimethoxy-, chloride (9CI); Berberine, chloride (6CI,7CI); Berbinium, 7,8,13,13a-tetradehydro-9,10-dimethoxy-2,3-(methylenedioxy)-,chloride (8CI); Berberinium chloride;
  • InChI:
  • InChI=1/C20H18NO4.ClH/c1-22-17-4-3-12-7-16-14-9-19-18(24-11-25-19)8-13(14)5-6-21(16)10-15(12)20(17)23-2;/h3-4,7-10H,5-6,11H2,1-2H3;1H/q+1;/p-1
  • This structure is also available as a 2d Mol file
Safety Data of 633-65-8 Properties of 633-65-8
  • Appearance:
  • yellow crystalline powder
  • Molecular Weight:
  • 371.82
  • Density:
  • 1.654g/cm3
  • Melting Point:
  • 200℃
  • Storage Temperature:
  • Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Store protected from light.
  • Solubility:
  • Water Solubility : SOLUBLE IN COLD WATER
  • Stability:
  • Stable under normal temperatures and pressures.
  • Usage:
  • An ingredient in some commercial eyewash products.

  • More>>

CAS No. 633-65-8 (Berberine hydrochloride )

  • CAS No:633-65-8
  • Molecular Weight: 371.82
  • Molecular Formula: C20H18NO4.Cl
Properties Safety and Handling MSDS NMR Spectrum Synthesis Route Precursor and Product
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Precursor and Product
References of Berberine hydrochloride cas 633-65-8

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 37mg/kg (37mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: EXCITEMENT

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Journal of Pharmacology and Experimental Therapeutics. Vol. 104, Pg. 253, 1952.
mouse LD50 oral > 29586mg/kg (29586mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) Kiso to Rinsho. Clinical Report. Vol. 8, Pg. 654, 1974.
mouse LD50 unreported 30mg/kg (30mg/kg) ? Pharmaceutical Chemistry Journal Vol. 22, Pg. 856, 1988.
rat LD50 intravenous 60mg/kg (60mg/kg) ? Zhongguo Yaoxue Zazhi. Chinese Pharmacuetical Journal. Vol. 25, Pg. 335, 1990.
rat LD50 oral > 15gm/kg (15000mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) Kiso to Rinsho. Clinical Report. Vol. 8, Pg. 654, 1974.

Safety

Safety Information of Berberine hydrochloride (CAS NO.633-65-8):
Hazard Codes: XnHarmful
Risk Statements: 20/21/22-36/37/38??
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.?
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 24/25-36-26
S24/25:Avoid contact with skin and eyes.?
S36:Wear suitable protective clothing.?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
RIDADR: 1544
WGK Germany: 2
RTECS: DR9866400
F: 3-10
HazardClass: 6.1(b)
PackingGroup: III

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