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Home> CAS DataBase Listed 7 > CAS 70-18-8
Identification of 70-18-8
  • Name:
  • Glutathione (Related Reference)
  • EINECS:
  • 200-725-4
  • Synonyms:
  • Glutathione(8CI); Glycine, N-(N-L-g-glutamyl-L-cysteinyl)-; Copren; Glutathion; Glutathione-SH; Glutide; Glutinal; Isethion; L-Glutathione; N-(N-L-g-Glutamyl-L-cysteinyl)glycine; Tathione; g-Glutamylcysteinylglycine; g-L-Glutamyl-L-cysteinylglycine; Glycine, L-g-glutamyl-L-cysteinyl-; GSH;
  • InChI:
  • InChI=1/C10H17N3O6S/c11-5(10(18)19)1-2-7(14)13-6(4-20)9(17)12-3-8(15)16/h5-6,20H,1-4,11H2,(H,12,17)(H,13,14)(H,15,16)(H,18,19)/t5-,6-/m0/s1
  • This structure is also available as a 2d Mol file
Safety Data of 70-18-8 Properties of 70-18-8
  • Appearance:
  • White Powder
  • Molecular Weight:
  • 307.32
  • Density:
  • 1.441 g/cm3
  • Boiling Point:
  • 410.1 ℃
  • Melting Point:
  • 182-192℃
  • Flash Point:
  • 754.5 ℃ at 760 mmHg
  • Alpha:
  • -16.5 ° (C=2, H2O)
  • Storage Temperature:
  • 2-8°C
  • Refractive index:
  • 1.571
  • Solubility:
  • Soluble
  • Stability:
  • Stable. Incompatible with strong oxidizing agents.
  • Usage:
  • Glutathione may decrease the concentrations of inflammatory cytokines (IL-6, IL-18), neutrophils in lung tissue and increase the level of serum Ca2+ and be useful for the treatment of ANP. Glutathione production is regulated via distinct pathways in stressed and non-stressed cortical neurons
  • More>>

CAS No. 70-18-8 (Glutathione )

  • CAS No:70-18-8
  • Molecular Weight: 307.32
  • Molecular Formula: C10H17N3O6S
Properties Safety and Handling MSDS NMR Spectrum Synthesis Route Precursor and Product
L-Glutathione reduced
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Precursor and Product
References of Glutathione cas 70-18-8

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intramuscular 4gm/kg (4000mg/kg) "Modern Pharmaceuticals of Japan, III," Tokyo, Japan Pharmaceutical, Medical and Dental Suppl Exporters' Assoc., 1968Vol. -, Pg. 97, 1968.
mouse LD50 intraperitoneal 4020mg/kg (4020mg/kg) "Modern Pharmaceuticals of Japan, IV," Tokyo, Japan Pharmaceutical, Medical and Dental Supply Exporters' Assoc., 1972Vol. -, Pg. 93, 1972.
mouse LD50 intravenous 2238mg/kg (2238mg/kg) Japanese Journal of Antibiotics. Vol. 38, Pg. 137, 1985.
mouse LD50 oral 5gm/kg (5000mg/kg) "Modern Pharmaceuticals of Japan, IV," Tokyo, Japan Pharmaceutical, Medical and Dental Supply Exporters' Assoc., 1972Vol. -, Pg. 93, 1972.
mouse LD50 subcutaneous 5gm/kg (5000mg/kg) "Modern Pharmaceuticals of Japan, IV," Tokyo, Japan Pharmaceutical, Medical and Dental Supply Exporters' Assoc., 1972Vol. -, Pg. 93, 1972.
rabbit LD50 intravenous > 2gm/kg (2000mg/kg) Biochemical Journal. Vol. 41, Pg. 325, 1947

Safety

Moderately toxic by intravenous route. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits very toxic fumes of SOx and NOx.
Hazard Codes:Xi
Risk Statements: 68-36/37/38
R68: Possible risk of irreversible effects.
R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements: 24/25-36/37/39-27-26
S24/25: Avoid contact with skin and eyes.
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.
S27: Take off immediately all contaminated clothing.
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany: 2
RTECS: MC0556000

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