|Organism||Test Type||Route||Reported Dose (Normalized Dose)||Effect||Source|
|man||TCLo||inhalation||44300ug/m3/8H (44.3mg/m3)||BEHAVIORAL: MUSCLE WEAKNESS
LIVER: OTHER CHANGES
|JOM, Journal of Occupational Medicine. Vol. 20, Pg. 532, 1978.|
|man||TDLo||intravenous||571uL/kg (0.571mL/kg)||PERIPHERAL NERVE AND SENSATION: PARESTHESIS
LUNGS, THORAX, OR RESPIRATION: DYSPNEA
SKIN AND APPENDAGES (SKIN): SWEATING: OTHER
|Southern Medical Journal. Vol. 90, Pg. 1033, 1997.|
|man||TDLo||multiple routes||86uL/kg (0.086mL/kg)||CARDIAC: PULSE RATE INCREASE WITHOUT FALL IN BP
LUNGS, THORAX, OR RESPIRATION: PULMONARY EMBOLI
SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"
|Journal of Toxicology, Clinical Toxicology. Vol. 38, Pg. 254, 2000.|
|man||TDLo||oral||43mg/kg (43mg/kg)||BEHAVIORAL: TREMOR
LIVER: "JAUNDICE, OTHER OR UNCLASSIFIED"
LIVER: OTHER CHANGES
|Journal of Toxicology, Clinical Toxicology. Vol. 31, Pg. 487, 1993.|
|man||TDLo||skin||129mg/kg/5H-C (129mg/kg)||SENSE ORGANS AND SPECIAL SENSES: TINNITUS: EAR
SKIN AND APPENDAGES (SKIN): "DERMATITIS, ALLERGIC: AFTER SYSTEMIC EXPOSURE"
|Dermatologica. Vol. 172, Pg. 48, 1986.|
|man||TDLo||subcutaneous||714uL/kg (0.714mL/kg)||SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"||Journal of Toxicology, Clinical Toxicology. Vol. 38, Pg. 441, 2000.|
|man||TDLo||subcutaneous||254mg/kg (254mg/kg)||SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"||Clinical Toxicology. Vol. 2, Pg. 243, 1969.|
|rabbit||LCLo||inhalation||29mg/m3/30H (29mg/m3)||?||AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 7, Pg. 19, 1953.|
|women||TCLo||inhalation||150ug/m3/46D (0.15mg/m3)||BEHAVIORAL: WAKEFULNESS
BEHAVIORAL: ANOREXIA (HUMAN
GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
|Archives of Environmental Health. Vol. 33, Pg. 186, 1978.|
Poison by inhalation. Human systemic effects by inhalation: wakefulness, muscle weakness, anorexia, headache, tinnitus, hypermotility, diarrhea, liver changes, dermatitis, fever. An experimental teratogen. Experimental reproductive effects. Questionable carcinogen with experimental tumorigenic data. Human mutation data reported. Used in dental applications, electronics, and chemical synthesis.
May explode on contact with 3-bromopropyne, alkynes + silver perchlorate, ethylene oxide, lithium, methylsilane + oxygen (explodes when shaken), peroxyformic acid, chlorine dioxide, tetracarbonylnickel + oxygen. May react with ammonia to form an explosive product. Mixtures with methyl azide are shock- and spark-sensitive explosives. The vapor ignites on contact with boron diiodophosphide. Reacts violently with acetylenic compounds (e.g., acetylene, sodium acetylide, 2-butyne-1,4-diol + acid), metals (e.g., aluminum, calcium, potassium, sodium, rubidium, exothermic formation of amalgams), Cl2, ClO2, CH3N3, Na2C2, nitromethane. Incompatible with methyl azide, oxidants. When heated to decomposition it emits toxic fumes of Hg.
Hazard Codes:? T?,N?,Xn?,C
Risk Statements:? 25-48/21/22-51/53-50/53-33-23-20/21/22-34-36/37/38-23/24/25
R25 :Toxic if swallowed.
R48/21/22:Harmful: danger of serious damage to health by prolonged exposure in contact with skin and if swallowed.
R51/53:Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
R50/53:Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.?
R33:Danger of cumulative effects.?
R23 :Toxic by inhalation.?
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.?
R36/37/38:Irritating to eyes, respiratory system and skin.
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed.
Safety Statements:? 7-45-60-61-36-36/37/39-26-36/37?
S7:Keep container tightly closed.?
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)?
S60:This material and its container must be disposed of as hazardous waste.?
S61:Avoid release to the environment. Refer to special instructions / safety data sheets.?
S36:Wear suitable protective clothing.?
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S36/37:Wear suitable protective clothing and gloves.
RIDADR:? UN 3289 6.1/PG 2
WGK Germany:? 3