2,2,2-Trifluoroethanol (cas 75-89-8) Molecular Structure

CAS No. 75-89-8 (2,2,2-Trifluoroethanol )

Molecular Formula: C2H3F3OMolecular Weight: 100.04

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    DetailDesc:Name: 2,2,2-Trifluoroethanol (Related Reference) EINECS: 200-913-6 Molecular Formula: C2H3F3O CAS Registry Number: 75-89-8 Synonyms: TFE; Trifluoroethanol; Trifluroroethyl alchohol InChI: InChI=1/C2H3F3O/c3-2(4,5)1-6/h6H,1H2 HS Code: 29055910

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References of 2,2,2-Trifluoroethanol cas 75-89-8

} Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LDLo intravenous 400mg/kg (400mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: DYSPNEA

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
Toxicology and Applied Pharmacology. Vol. 15, Pg. 83, 1969.
mouse LC50 inhalation 2900mg/m3 (2900mg/m3) BRAIN AND COVERINGS: "CHANGES IN CIRCULATION (HEMORRHAGE, THROMBOSIS, ETC.)"

BEHAVIORAL: GENERAL ANESTHETIC

LUNGS, THORAX, OR RESPIRATION: STRUCTURAL OR FUNCTIONAL CHANGE IN TRACHEA OR BRONCHI
Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 13(10), Pg. 29, 1969.
mouse LD50 intraperitoneal 158mg/kg (158mg/kg) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) Annales Medicinae Experimentalis et Biologiae Fenniae. Vol. 46, Pg. 242, 1968.
mouse LD50 intravenous 250mg/kg (250mg/kg) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) Annales Medicinae Experimentalis et Biologiae Fenniae. Vol. 46, Pg. 242, 1968.
mouse LD50 oral 366mg/kg (366mg/kg) BEHAVIORAL: TREMOR

LUNGS, THORAX, OR RESPIRATION: DYSPNEA

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS
Toxicology and Applied Pharmacology. Vol. 15, Pg. 83, 1969.
rabbit LD50 skin 390uL/kg (0.39mL/kg) SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE" National Technical Information Service. Vol. OTS0555986,
rat LC50 inhalation 470ppm/6H (470ppm) BEHAVIORAL: TREMOR

BEHAVIORAL: ATAXIA

SKIN AND APPENDAGES (SKIN): HAIR: OTHER
National Technical Information Service. Vol. OTS0555986,
rat LD50 intraperitoneal 210mg/kg (210mg/kg) ? Toxicology and Applied Pharmacology. Vol. 71, Pg. 84, 1983.
rat LD50 oral 240mg/kg (240mg/kg) ? "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 607, 1969.
rat LD50 skin 1680mg/kg (1680mg/kg) ? "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 607, 1969.

Safety

Poison by ingestion, intravenous, and intraperitoneal routes. Moderately toxic by inhalation and skin contact. Experimental reproductive effects. A severe skin and eye irritant. When heated to decomposition it emits toxic fumes of F?.
Hazard Codes:?Xn, T, F
Hazard Note: Flammable/Toxic
The Risk Statements information of?2,2,2-Trifluoroethanol (CAS NO.75-89-8):
10:? Flammable?
41:? Risk of serious damage to eyes?
62:? Possible risk of impaired fertility?
20/21/22:? Harmful by inhalation, in contact with skin and if swallowed?
37/38:? Irritating to respiratory system and skin?
36/37/38:? Irritating to eyes, respiratory system and skin?
The Safety Statements information of??2,2,2-Trifluoroethanol (CAS NO.75-89-8):
16:? Keep away from sources of ignition - No smoking?
26:? In case of contact with eyes, rinse immediately with plenty of water and seek medical advice?
36:? Wear suitable protective clothing?
39:? Wear eye/face protection?
45:? In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)?
36/37/39:? Wear suitable protective clothing, gloves and eye/face protection??
RIDADR: UN 1986 3/PG 3
WGK Germany: 1
RTECS: KM5250000
Hazard Note: Flammable/Toxic
HazardClass: 3
PackingGroup: III
HS Code: 29055910