vinblastine (cas 865-21-4) Molecular Structure

CAS No. 865-21-4 (vinblastine )

Molecular Formula: C46H58N4O9Molecular Weight: 810.9856

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    DetailDesc:Name: vinblastine Synonyms: Vincaleukoblastine; CAS Registry number: 865-21-4 EINECS:212-734-0 Molecular Formula: C46H58N4O9 Density: 1.37 g/cm 3 Appearance: POWDER Transport:1544

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    DetailDesc: VINBLASTINE Name: VINBLASTINE Synonym: Vincaleukoblastine;(+)-CATHRANTHINE CAS: 865-21-4 EINECS: 212-734-0 Assay: NLT98% M.F: C46H58N4O9 M.W: 810.97 MP: 211 - 216 oC Density: 1.37 g/cm3 Appearance: Application: For the treatment of malignant lymphoma Package: 1g/foil bag MOQ: 1g Price: 200USD/G

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    DetailDesc: Vinblastine 【 Synonyms 】 Vinblastine 【 CAS No. 】 865-21-4 【 Mol. Formula 】 C46H58N4O9 【 M ol. Weight 】 810.97 【 Botanical Source 】 Catharanthus roseus(L.)G Don 【 Loss on drying 】 ≤ 2.0% 【 Catalogue No. 】 C-002 【 Purity 】 >98% 99% by HPLC 【 Packaging 】 20m...

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  • Vinblastine // CAS NO.:865-21-4

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    DetailDesc: 1.Description Product name:Vinblastine Latin Name:Catharanthus roseus CAS: 865-21-4 molecular formula:C46H58N4O9 Active ingredients:Vinblastine Part used:Whole herb Assay:98% Appearance: White powder Test method:HPLC 2.Introduction Vinblastine is a vinca alkaloid and a chemical ...

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References of vinblastine cas 865-21-4

} Toxicity

1.    

dni-hmn:oth 200 µg/L

    26QZAP    Advances in Antimicrobial and Antineoplastic Chemotherapy, Progress in Research and Clinical Application. 2 (1972),377.
2.    

cyt-mus-ipr 900 µg/kg

    ENMUDM    Environmental Mutagenesis. 8 (1986),273.
3.    

ivn-man LDLo:2319 µg/kg/38W-I:CVS

    LANCAO    Lancet. 2 (1980),692.
4.    

ocu-hmn TDLo:14 µg/kg:EYE

    BJOPAL    British Journal of Ophthalmology. 62 (1978),97.
5.    

unr-man TDLo:80 µg/kg:BLD

    CCROBU    Cancer Chemotherapy Reports, Part 1. 50 (1966),219.
6.    

ipr-rat LD50:1 mg/kg

    VINIT*    Vsesoyuznyi Institut Nauchnoi i Tekhnicheskoi Informatsii (VINITI). All-Union Institute of Scientific and Technical Information. (Moscow, USSR) #3713-83 .

Safety

Human poison by intravenous route. Experimental poison by intraperitoneal route. Human systemic effects by intravenous and ocular routes: visual field changes, conjunctiva irritation and other eye effects, cardiomyopathy including infarction, and changes in bone marrow. Experimental teratogenic and reproductive effects. Questionable carcinogen with experimental tumorigenic data. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx. Used as an antineoplastic agent. See also VINCALEUKOBLASTINE SULFATE (1:1) (SALT).
RIDADR: 1544
HazardClass: 6.1(a)
PackingGroup: II