Benzotriazole (BT) is an anticorrosive agent well known for its use in aircraft deicing and antifreeze fluids but also used in dishwasher detergents.
|Organism||Test Type||Route||Reported Dose (Normalized Dose)||Effect||Source|
|guinea pig||LD50||oral||500mg/kg (500mg/kg)||AUTONOMIC NERVOUS SYSTEM: OTHER (DIRECT) PARASYMPATHOMIMETIC
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
LUNGS, THORAX, OR RESPIRATION: CYANOSIS
|Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 46(11), Pg. 70, 1981.|
|mouse||LD50||intraperitoneal||400mg/kg (400mg/kg)||?||Farmakologiya i Toksikologiya Vol. 41, Pg. 708, 1978.
Link to PubMed
|mouse||LD50||intravenous||238mg/kg (238mg/kg)||?||Journal of Pharmacology and Experimental Therapeutics. Vol. 105, Pg. 486, 1952.
Link to PubMed
|mouse||LD50||oral||615mg/kg (615mg/kg)||?||National Technical Information Service. Vol. AD-A067-313,|
|rabbit||LDLo||skin||450mg/kg (450mg/kg)||?||National Technical Information Service. Vol. OTS0520182,|
|rat||LC50||inhalation||1910mg/m3/3H (1910mg/m3)||LUNGS, THORAX, OR RESPIRATION: STRUCTURAL OR FUNCTIONAL CHANGE IN TRACHEA OR BRONCHI
LUNGS, THORAX, OR RESPIRATION: DYSPNEA
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
|National Technical Information Service. Vol. OTS0520637,|
|rat||LD50||oral||560mg/kg (560mg/kg)||?||National Technical Information Service. Vol. OTS0516797,|
|rat||LD50||skin||> 1gm/kg (1000mg/kg)||?||National Technical Information Service. Vol. OTS0516745,|
? 1H-Benzotriazole (CAS NO.95-14-7) hasn't been listed as a carcinogen by NTP, IARC, ACGIH, or CA Prop 65. And the toxicological properties have not been fully investigated. You can see actual entry in RTECS for complete information.
Risk Statements: 20/22-36-52/53-5-36/37/38-20/21/22-11
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.?
R20/22:Harmful by inhalation and if swallowed.?
R36/37/38:Irritating to eyes, respiratory system and skin.?
R36:Irritating to eyes.?
R52/53:Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Safety Statements: 26-36/37-61-45-36/37/39-28A?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S28:After contact with skin, wash immediately with plenty of soap-suds.
S36/37:Wear suitable protective clothing and gloves.?
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.?
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)?
S61:Avoid release to the environment. Refer to special instructions / safety data sheets.