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Home> CAS DataBase Listed 9 > CAS 97240-79-4
Identification of 97240-79-4
  • Name:
  • Topiramate (Related Reference)
  • Synonyms:
  • McN-4853; Epitomax; 2,3:4,5-bis-o-(1-methylethylidene)-beta-d-fructopyranos sulfamate; a-D-Fructopyranose,2,3:4,5-bis-O-(1-methylethylidene)-,sulfamate; Tipiramato [Spanish]; Topamax; Topiramate [USAN:BAN:INN]; 2,3:4,5-Bis-O-(1-methylethylidene)-beta-D-fructopyranose sulfamate; beta-D-Fructopyranose, 2,3:4,5-bis-O-(1-methylethylidene)-, sulfamate; Topiramate; Topamax; RWJ-17021-000; 2,3:4,5-Di-O-isopropylidene-beta-D-fructopyranose sulfamate; Topiramate (JAN/USAN); Tipiramate [French]; Topamax (TN);
  • This structure is also available as a 2d Mol file
Safety Data of 97240-79-4 Properties of 97240-79-4
  • Appearance:
  • white to off-white crystalline powder
  • Molecular Weight:
  • 339.36
  • Density:
  • 1.336 g/cm3
  • Boiling Point:
  • 438.7 °C at 760 mmHg
  • Melting Point:
  • 125℃
  • Flash Point:
  • 219.1 °C
  • Storage Temperature:
  • 2-8°C
  • Refractive index:
  • 1.497
  • Solubility:
  • DMSO Solubility : ~44 mg/mL
  • Biological Activity:
  • Anticonvulsant. Antagonizes GluR5 kainate receptors (IC 50 = 0.46 μ M), acts as a positive allosteric modulator of GABA A receptor-mediated currents, inhibits Na v channels (IC 50 = 48.9 μ M) and inhibits L-type Ca 2+ channels. Also inhibits carbonic anhydrase (CA) (K i values are 0.1 and 0.2 μ M at rat CA II and CA IV respectively), which lowers intracellular neuronal pH.
  • Stability:
  • Stable if stored as directed.
  • Usage:
  • Used as an anticonvulsant

  • More>>

CAS No. 97240-79-4 (Topiramate )

  • CAS No:97240-79-4
  • Molecular Weight: 339.36
  • Molecular Formula: C12H21NO8S
Properties Safety and Handling MSDS NMR Spectrum Synthesis Route Precursor and Product
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Precursor and Product
References of Topiramate cas 97240-79-4

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
rat LD50 intraperitoneal > 1500mg/kg (1500mg/kg) ? Drugs of the Future. Vol. 14, Pg. 342, 1989.

Safety

Safety Information of Topiramate (CAS NO. 97240-79-4):
Hazard Codes: Xi?Irritant
Risk Statements: 36/37/38
R36/37/38:Irritating to eyes, respiratory system and skin
Safety Statements: 26-36
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36:Wear suitable protective clothing
WGK Germany: 3
RTECS: LS7083000