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Home> Products > Pharmaceuticals and Biochemicals > Dermatological agents > CAS DataBase Listed 1 > CAS 106685-40-9
106685-40-9 structure

CAS 106685-40-9 Adapalene products price,suppliers

  • White Crystalline SolidChEBI: A naphthoic acid that is CD437 in which the phenolic hydroxy group has been converted to its methyl ether.Adapalene, a new class of drugs Naphthoic acid derivatives, was developed by France Galdeama Laboratories Company. It first entered into market in June 1996, under the trade name ''Differin'', mainly used for relieving inflammatory skin lesions, adjusting differentiation of hair follicles, gland epithelial cells, and also acne treatment.


    Solid


    Adapalene is a naphthoic acid that is CD437 in which the phenolic hydroxy group has been converted to its methyl ether. It has a role as a dermatologic drug, a non-steroidal anti-inflammatory drug and an EC 2.7.11.22 (cyclin-dependent kinase) inhibitor. It is a monocarboxylic acid, a member of adamantanes and a naphthoic acid. It derives from a CD437.|Acne vulgaris is a multifactorial disorder of the pilosebaceous unit involving increased sebum production, inflammation, and hyperproliferation/hyperkeratinization of the follicular infundibulum. It is also associated with Cutibacterium acnes (also known as Propionibacterium acnes). Adapalene is a third-generation topical retinoid used for the treatment of acne vulgaris. Adapalene has similar efficacy but a superior safety profile compared to tretinoin. [Tazarotene] is more efficacious than adapalene but is designated as pregnancy category X and hence is contraindicated in pregnant women. Adapalene can also be combined with benzoyl peroxide (BPO), which possesses bactericidal properties, and either adapalene alone, or adapalene BPO combination products, are commonly used to treat mild-to-severe acne. Differin?, produced by Galderma Labs, was first granted FDA approval on May 31st, 1996, as a 0.1% adapalene topical solution. Differin was later made available as 0.1% gel, cream, or lotion, or 0.3% gel products. On December 8th, 2008, Galderma Labs gained FDA approval for Epiduo?, a 0.1% adapalene, 2.5% BPO combination gel.|Adapalene is a Retinoid.|Adapalene is a topical retinoid-like compound, chemically similar to vitamin A. Although the exact mechanism of action is unknown, adapalene binds to specific retinoic acid receptors in the nucleus, leading to specific gene expression. This agent stimulates skin growth through modulation of cellular differentiation, inflammatory processes and keratinization of follicular epithelial cells. Adapalene may increase dermal sensitivity to ultraviolet radiation. (NCI04)|A naphthalene derivative that has specificity for RETINOIC ACID RECEPTORS. It is used as a DERMATOLOGIC AGENT for the treatment of ACNE.

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  • Name: Adapalene
  • Molecular Weight: 412.52012
  • Formula: C28H28O3
  • Synonyms: 2-Naphthalenecarboxylic acid, 6-(4-methoxy-3-tricyclo[3.3.1.1]dec-1-ylphenyl)-; 6-(3-(Adamantan-1-yl)-4-methoxyphenyl)-2-naphthoic acid; 6-(4-methoxy-3-tricyclo[3.3.1.1]dec-1-ylphenyl)naphthalene-2-carboxylic acid; 6-(4-Methoxy-3-tricyclo[3.3.1.13,7]dec-1-ylphenyl)-2-naphthalenecarboxylic Acid; 6-[3-(1-ADAMANTYL)-4-METHOXYPHENYL]-2-NAPHTHALENE CARBOXYLIC ACID; 6-[3-(1-ADAMANTYL)-4-METHOXYPHENYL]-2-NAPHTHOIC ACID;
Properties Safety and Handling MSDS Synthesis Route Precursor and Product Computational chemical data
Identification
  • Cas NO.:106685-40-9
  • CID:60164
  • Name:
  • Adapalene (Related Reference)
  • EINECS:
  • 1308068-626-2
  • InChI:
  • InChI=1S/C28H28O3/c1-31-26-7-6-23(21-2-3-22-12-24(27(29)30)5-4-20(22)11-21)13-25(26)28-14-17-8-18(15-28)10-19(9-17)16-28/h2-7,11-13,17-19H,8-10,14-16H2,1H3,(H,29,30)
Safety Data
Properties
  • Molecular Weight:
  • 412.52012
  • Density:
  • 1.233
  • Boiling Point:
  • 606.3 °C at 760 mmHg
  • Melting Point:
  • 319-322 °C
  • Flash Point:
  • 205.9 °C
  • Storage Temperature:
  • 2-8°C
  • Refractive index:
  • 1.654
  • Solubility:
  • Practically insoluble in water;DMSO: >10mg/mL
  • More Properties>>
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Factory Supply Adapalene CAS 106685-40-9
Factory Supply Adapalene CAS 106685-40-9
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High Quality Pharmaceutical API Adapalene Powder CAS 106685-40-9
High Quality Pharmaceutical API Adapalene Powder CAS 106685-...
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WHXJ CAS 106685-40-9 Adapalene C28H28O3
WHXJ CAS 106685-40-9 Adapalene C28H28O3
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Adapalene White powder
Adapalene White powder
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  • Updatetime:May 30 2023 
AdapaleneCAS NO.: 106685-40-9
AdapaleneCAS NO.: 106685-40-9
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  • Description:Product Description Packaging & Delivery Packaging Detail: 1kg/bag Delivery
  • Updatetime:May 18 2023 
AdapaleneCAS NO.: 106685-40-9
AdapaleneCAS NO.: 106685-40-9
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  • Description:CAS: 106685-40-9
  • Updatetime:May 11 2023 
Adapalene 106685-40-9 API low price hot sell in stock
Adapalene 106685-40-9 API low price hot sell in stock
  • FOB Price:1 USD/kilogram 
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  • Appearance:white powder 
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  • Usage:Chemical drugs 
  • Brand:Hubei Jiutian 
  • Description:Adapalen;ADAPALENE;6-[3-(1-ADAMANTYL)-4-METHOXYPHENYL]-2-NAPHTHALENE CARBOXYLIC ACID;6-[3-(1-ADAMANTYL)-4-METHOXYPHENYL]-2-NAPHTHOIC ACID;6-[3-(1-adamantyl)-4-methoxy-phenyl]naphthalene-2-carboxylic acid;6-(4-Methoxy
  • Updatetime:Feb 03 2023 
Adapalene
Adapalene
  • FOB Price:10 USD/kilogram 
  • Min.Order:1 Kilogram 
  • Supply Ability:1 Metric Ton/Month 
  • Appearance:White Crystalline Solid 
  • Purity:99% 
  • Packaging:25KG/CARTON or 25kg/drum or as customers requirement 
  • Usage: Antiacne 
  • Brand:royal 
  • Description:Adapalene Basic information Product Name: Adapalene Synonyms: ADAPALENE;6-[3-(1-ADAMANTYL)-4-METHOXYPHENYL]-2-NAPHTHALENE CARBOXYLIC ACID;6-[3-(1-ADAMANTYL)-4-METHOXYPHENYL]-2-NAPHTHOIC ACID;
  • Updatetime:Mar 14 2023 
Adapalene CAS:106685-40-9 white powder
Adapalene CAS:106685-40-9 white powder
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  • Appearance:white powder 
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  • Packaging:<1kg,Aluminium foil paper packaging;1kg-25kg,Plastic sealed packaging and drums 
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  • Description:Adapalene Basic information
  • Updatetime:Apr 25 2023 
Factory Supply Adapalene
Factory Supply Adapalene
  • FOB Price:0.1 USD/kilogram 
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  • Appearance:solid or liquid ( refer to COA) 
  • Purity:99.90% 
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  • Usage:upon client's application 
  • Brand:Amitychem 
  • Description:Amitychem Corporation manufacture and supply Adapalene with with high quality, low price and bulk supply. We have been focusing on the research and production of concrete chemicals for 14+ years. Our product quality has ISO, SGS, CQC,FAMI-QS, etc. Cetificated....
  • Updatetime:Mar 01 2023 
Factory supply Adapalene Cas 106685-40-9 with high quality and best price
Factory supply Adapalene Cas 106685-40-9 with high quality a...
  • Min.Order:100 Gram 
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  • Appearance:White to off-white crystalline powder 
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  • Description:Factory supply Adapalene Cas 106685-40-9 with high quality and best price
  • Updatetime:May 29 2023 
Adapalene 106685-40-9
Adapalene 106685-40-9
  • FOB Price:65 USD/kg 
  • Min.Order:1 KG 
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  • Packaging:According to customers request. 
  • Brand:zhurong 
  • Description:Adapalene. Adapalene CAS number 106685-40-9 Molecular weight 412.520
  • Updatetime:May 22 2023 
Adapalene manufacture
Adapalene manufacture
  • Appearance:Detailed see specifications 
  • Purity:98.0% 
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  • Description:Superiority hangzhou zeerrui chemical co., ltd. located in lingang industrial areas, our plant covers an area of 6000 square meters.zeerrui dedicated to the development, production and marketing of chemicals. we have earned ourselves a good reputation at home ...
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Adapalene
Adapalene
  • Min.Order:1 Kilogram 
  • Purity:99% 
  • Usage:Intermediate 
  • Brand:Luyunjia 
  • Description:Name: Adapalene Synonyms: I810; A2549; s1276; CD271; NAP030; D01112; S-3513; CD 271; CD-271; Differi; 685A409; A801483; Q352348; AOB6389; AB13763; AC-1974; CS-1789; DB00210; KS-1196; AK-72900; C28H28O3; Adaferin; GTPL5429; BCP02081; EBD19549; HY-B0091; SC-1732...
  • Updatetime:May 11 2023 
Adapalene
Adapalene
  • Purity:99% 
  • Description:Adapalene
  • Updatetime:Apr 23 2023 
Adapalene CAS. 106685-40-9
Adapalene CAS. 106685-40-9
  • FOB Price:29 USD/kg 
  • Min.Order:1 KG 
  • Supply Ability:3000 MT/Month 
  • Appearance:White to grayish white crystalline powder 
  • Purity:99% 
  • Packaging:customization 
  • Usage:a synthetic retinoic acid and an agonist of retinoic acid receptor (RAR). 
  • Brand:YOUZE 
  • Description:Quick Details Classification: Pharmaceutical Intermediates Cas NO.:106685-40-9 Name: Adapalene Formula: C28H28O3 Boiling Point:
  • Updatetime:Nov 25 2022 
Adapalene
Adapalene
  • FOB Price:1 USD/kilogram 
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  • Appearance:a white or almost white crystalline powder 
  • Purity:99% 
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  • Brand:Adapalene 
  • Description:Product Description R&D, intermediates. Packing&Delivery
  • Updatetime:Nov 15 2022 
Factory Supply Adapalene CAS 106685-40-9
Factory Supply Adapalene CAS 106685-40-9
  • FOB Price:1 USD/kilogram 
  • Min.Order:1 Kilogram 
  • Supply Ability:10 Metric Ton/Month 
  • Appearance:Powder 
  • Purity:99.0%min 
  • Packaging:As requested 
  • Usage:Pharmaceutical intermediates whatsapp:+8617065658228 
  • Brand:BT 
  • Description:Product Details About Us We are a large factory, a professional export department, perfect after-sales service. There are professional technology research and development department, each product is after countless tests, after the success of processing produc...
  • Updatetime:Feb 28 2022 
Adapalene
Adapalene
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  • Appearance:White powder 
  • Purity:99% 
  • Packaging:25Kg/drum; 1kg/bag 
  • Usage:Pharmaceutical intermediate 
  • Brand:Tianhua 
  • Description:Product Name: Adapalene CAS: 106685-40-9 MF: C28H28O3 MW: 412.52 EINECS: 620-513-9 Melting point 319-3220C
  • Updatetime:Feb 01 2021 
Adapalene
Adapalene
  • FOB Price:1 USD/gram 
  • Min.Order:10 Gram 
  • Supply Ability:10 Metric Ton/Month 
  • Appearance:White Powder 
  • Purity:99.9% 
  • Packaging:Customized 
  • Usage:Pharmaceutical Intermediates 
  • Brand:Yijing 
  • Description:Adapalene Synonyms: ADAPALENE;6-[3-(1-ADAMANTYL)-4-METHOXYPHENYL]-2-NAPHTHALENE CARBOXYLIC ACID;6-[3-(1-ADAMANTYL)-4-METHOXYPHENYL]-2-NAPHTHOIC ACID;6-[3-(1-adamantyl)-4-methoxy-phenyl]naphthalene-2-carboxylic acid;Adapalen;6-(4-Methoxy-3-tricyclo[3.3.1.13,7]d...
  • Updatetime:Apr 25 2017 
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