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Home> Products > Pharmaceuticals and Biochemicals > Central Nervous System Agents > CAS DataBase Listed 1 > CAS 119356-77-3
119356-77-3 structure

CAS 119356-77-3 Dapoxetine products price,suppliers

  • Premature ejaculation (PE) is the most common male sexual dysfunction. Dapoxetine hydrochloride,marketed as Priligy and Westoxetin, is a class of PE treatment drugs known as selective serotonin reuptake inhibitors (SSRI) , was the first drug originally approved for the on-demand treatment of men 18–64 years old with PE. Dapoxetine works by inhibiting the serotonin transporter, increasing serotonin's action at the post synaptic cleft, and as a result promoting ejaculatory delay.


    Dapoxetine is a member of naphthalenes.|Dapoxetine is a selective serotonin reuptake inhibitor, for the treatment of premature ejaculation. In a phase II proof-of-concept study conducted by PPD, dapoxetine demonstrated a statistically significant increase in ejaculatory latency when compared to placebo. Alza submitted a NDA to the FDA for dapoxetine for the treatment of premature ejaculation in December 2004. In October 2005, the company received a FDA Non-Approvable letter from the FDA, at which time they planned to work with regulators to address outstanding questions.

  • + show more
  • Name: Dapoxetine
  • Molecular Weight: 305.421
  • Formula: C21H23NO
  • Synonyms: (+)-N,N-Dimethyl-a-(2-(1-naphthalenyloxy)ethyl)benzenemethanamine; (1S)-N,N-Dimethyl-3-(1-naphthyloxy)-1-phenyl-1-propanamine; (1s)-n,n-dimethyl-3-(1-naphthyloxy)-1-phenylpropan-1-amine; (1S)-N,N-dimethyl-3-(naphthalen-1-yloxy)-1-phenylpropan-1-amine; (1S)-N,N-dimethyl-3-naphthalen-1-yloxy-1-phenylpropan-1-amine; (S)-(+)-Dapoxetine;
Properties Safety and Handling MSDS NMR Spectrum Computational chemical data
Identification
  • Cas NO.:119356-77-3
  • CID:71353
  • Name:
  • Dapoxetine (Related Reference)
  • EINECS:
  • 1308068-626-2
  • InChI:
  • InChI=1S/C21H23NO/c1-22(2)20(18-10-4-3-5-11-18)15-16-23-21-14-8-12-17-9-6-7-13-19(17)21/h3-14,20H,15-16H2,1-2H3/t20-/m0/s1
Safety Data
Properties
  • Molecular Weight:
  • 305.421
  • Density:
  • 1.081
  • Boiling Point:
  • 454.4°Cat760mmHg
  • Flash Point:
  • 132.6°C
  • Refractive index:
  • 1.607
  • More Properties>>
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  • Description:Density 1.1±0.1 g/cm3 Boiling point 454.4±38.0 °C at 760 mmHg Molecular formula C21H23NO Molecular weight 305.413 Flash point 132.6±29.1 °C Precise mass 305.177979 PSA 12.47000 LogP 5.13 Appearance White to off-white crystalline powder Vapor pressure 0.0±1.1 m...
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  • Description:Dapoxetine aliase:Priligy; Dapoxetina;Dapoxetinum;(1S)-N,N-dimethyl-3-naphthalen-1-yloxy-1-phenylpropan-1-amine; CAS NO.:119356-77-3 molecular formula:C21H23NO molecular weight:305.41300 accurate mass:305.17800
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  • Description:Product Description Density 1.1±0.1 g/cm3 Boiling Point 454.4±38.0 °C at 760 mmHg Molecular Formula C21H23NO Molecular Weight 305.413 Flash Point 132.6±29.1 °C Exact Mass 305.177979 PSA 12.47000 LogP
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