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Home> Products > Pharmaceuticals and Biochemicals > Immune Function Agents > CAS DataBase Listed 1 > CAS 154598-52-4
154598-52-4 structure

CAS 154598-52-4 Efavirenz | Products & Prices & Suppliers

  • White to Slightly Pink Crystalline PowderChEBI: 1,4-Dihydro-2H-3,1-benzoxazin-2-one substituted at the 4 position by cyclopropylethynyl and trifluoromethyl groups (S configuration) and at the 6 position by chlorine. A non-nucleoside reverse transcriptase inhibitor wit activity against HIV, it is used with other antiretrovirals for combination therapy of HIV infection.Efavirenz D5 was launched as Sustiva in the US for the treatment of infection by HIV, the virus causing AIDS, in combination wi
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  • Name: Efavirenz
  • Molecular Weight: 315.676
  • Formula: C14H9ClF3NO2
  • Synonyms: (4S)-6-Chloro-4-(cyclopropylethynyl)-4-(trifluoromethyl)-1,4-dihydro-2H-3,1-benzoxazin-2-one; (4S)-6-Chloro-4-(cyclopropylethynyl)-4-(trifluoromethyl)-4H-3,1-benzoxazin-2-ol; (S)-6-chloro-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-2H-3,1-benzoxazin-2-one; 2H-3,1-Benzoxazin-2-one, 6-chloro-4-(2-cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-, (4S)-; 4H-3,1-Benzoxazin-2-ol, 6-chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-, (4S)-; DMP 266;
Properties Safety and Handling MSDS Synthesis Route Precursor and Product Computational chemical data
Identification
Safety Data
  • [Risk Codes]
  • [Safety Statements]
Properties
  • Molecular Weight:
  • 315.676
  • Density:
  • 1.53
  • Boiling Point:
  • 340.6 °C at 760 mmHg
  • Melting Point:
  • 139-141°C
  • Flash Point:
  • 159.8 °C
  • Alpha:
  • D20 -84.7° (c = 0.005 g/ml in CH3Cl); D25 -94.1° (c = 0.300 in methanol)
  • Storage Temperature:
  • <0°C
  • Refractive index:
  • 1.58
  • Solubility:
  • In water, 0.093 mg/L @ 25 deg C /Estimated/
  • More Properties>>
Question & Answer
Upstream Product Downtream information
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High Purity Intermediates China Supply 99% Purity CAS 154598-52-4 Efavirenz
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Efavirenz CAS 154598-52-4
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  • Description:Efavirenz CAS 154598-52-4 Product Description Product Name: Efavirenz Synonyms: (S)-6-Chloro-4-(cyclopropylethynyl)-4-(trifluoromethyl)-1H-benzo[d][1,3]oxazin-2(4H)-one CAS No. 154598-52-4
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  • Description:CAS 154598-52-4 Efavirenz Efavirenz is a potent inhibitor of the wild-type HIV-1 reverse transcriptase with a Ki of 2.93 nM and exhibits an IC95 of 1.5 nM for the inhibition of HIV-1 replicative spread in cell culture.
  • Updatetime:Sep 27 2023 
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Efavirenz cas154598-52-4
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High purity low price Efavirenz CAS 154598-52-4
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  • Brand:Amitychem 
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Efavirenz
Efavirenz
  • FOB Price: USD/kilogram 
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  • Description:Name : efavirenz Synonyms : (4S)-6-chloro-4-(2-cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)- 2H-3,1-Benzoxazin-2-one;(-)-Efavirenz; Stocrin; Sustiva CAS Registry Number : 154598-52-4
  • Updatetime:Jul 07 2023 
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  • Description:Quick Details Common Name Efavirenz CAS Number 154598-52-4 Molecular Weight 315.675 Density 1.5±0.1 g/cm3 Boiling Point
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Efavirenz
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Hot sell High Quality Efavirenz (CAS 	154598-52-4)
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