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Home> Products > Pharmaceuticals and Biochemicals > Antineoplastic Agents > CAS DataBase Listed 1 > CAS 184475-35-2
184475-35-2 structure 3D

CAS 184475-35-2 alamethicin alpha products price,suppliers

  • Name: alamethicin alpha
  • Molecular Weight: 446.907
  • Formula: C17H17N5OS
  • Synonyms: (3-chloro-4-fluoro-phenyl)-[7-methoxy-6-(3-morpholin-4-yl-propoxy)-quinazolin-4-yl]-amine; (3-chloro-4-fluoro-phenyl)-[7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-yl]amine; (3-chloro-4-fluorophenyl)[7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-yl]amine; 15215-EP2269994A1; 15215-EP2272827A1; 15215-EP2272832A1;
  • Light-Yellow Crystalline PowderGefitinib was introduced in Japan as a daily oral monotherapy for the treatment ofinoperable or recurrent non-small cell lung cancers (NSCLC). This anilinoquinazolinederivative can be synthesized in 6 steps starting from 6,7-dimethoxyquinazolin-4(3H)-oneby successive monodemethylationlacetylation of the 6-hydroxy-group followed bychlorination and reaction with 3-chloro-4-fluoroaniline, finally deacetylation and alkylationwith 3-(4-morpholinyl)propylbromi
Properties Safety and Handling MSDS NMR Spectrum Synthesis Route Precursor and Product Computational chemical data
Identification Safety Data
  • [Safety Statements]
Properties
  • Appearance:
  • Light-Yellow Crystalline Powder
  • Molecular Weight:
  • 446.907
  • Boiling Point:
  • 399.8±42.0 °C(Predicted)
  • Melting Point:
  • 119-120
  • Storage Temperature:
  • Store at RT
  • Refractive index:
  • 1.621
  • More Properties>>
Question & Answer
  • How does gefitinib affect the EGFR(ecptor) and why is there relapse Gefitinib has been shown to be an effective tyrosine kinase inhibitor in a fraction (~ 10 " style="position: relative;" tabindex="0" id="MathJax-Element-2-Frame" class="MathJax" 10 10 %) of non-small cell lung cancer patients. These patients are characterized as having a mutation (usually a deletio...more+ Aug 03 2021
  • Gefitinib: Uses in non-small cell lung cancer (NSCLC) Imatinib mesylate is a novel tyrosine kinase inhibitor and a derivative of phenylpyrimidine. About 95% of patients with chronic myeloid leukemia (CML) are Philadelphia chromosome-positive, that is, the proto-oncogene ABL of chromosome 9 is ectopic to the oncogene of chromosome 22 called the breakpo...more+ Apr 01 2021
Upstream Product Downtream information
There are 474 suppliers who can provide alamethicin alpha with CAS No. 184475-35-2
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  • Description:gefitinib (Iressa, ZD-1839) is an EGFR inhibitor for Tyr1173, Tyr992, Tyr1173 and Tyr992 in the NR6wtEGFR and NR6W cells with IC50 of 37 nM, 37nM, 26 nM and 57 nM, respectively.
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  • Description:Name:Gefitinib Cas No.:184475-35-2 Molecular Formula:C22H24ClFN4O3 Formula Weight:446.91 Appearance: white powder Application: use of non small cell lung cancer(NSCLC)
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Legal Gefitinib Manuafcturer CAS 184475-35-2
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  • Appearance:Earthy yellow crystalline powder 
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  • Description:technical data: m. wt: 446.9 formula: c22h24clfn4o3 storage: store at rt purity: ≥98% (hplc) cas number: 184475-35-2
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  • Description:Name: Gefitinib Synonyms: N-(3-chloro-4-fluoro-phenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine;ZD1839;4-(3-Chloro-4-fluoroanilino)-7-methoxy-6-(3-morpholinopropoxy)quinazoline;Irressat;Gefitinib (JAN/USAN);4-Quinazolinamine, N-(3-chloro-4-fluor...
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  • Updatetime:Apr 25 2021 
N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine
N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholin-4-ylpro...
  • Purity:97.00% 
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Gefitinib Iressa 184475-35-2 Cancer Treatment Steroids for Antineoplastic
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Top quality of Gefitinib(CAS:184475-35-2)
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  • Description:Top quality of Gefitinib(CAS:184475-35-2) Synonyms:Irressat;Gefitinib (JAN/USAN);4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]- CAS:184475-35-2 Formula: C22H24ClFN4O3 Molecular Weight: 446.90 . Density:1.322 g/cm3 Meltin...
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  • Description:Gefitinib Synonyms: IRESSA;GEFITINIB;AKOS 91371;n-(3-chloro-4-fluoro-phenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine;N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine;ZD 1839;4-Quinazolinamine, N-(3-chloro-4-f...
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  • Description:COMPANY PROFILE 1.Cooperate with research institutions, we strictly control the process from raw material to finished product. • 2.The customer comes first, we provide reasonable pr
  • Updatetime:Nov 11 2020 
Gefitinib powder CAS NO.184475-35-2
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  • FOB Price:10 USD/Gram 
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  • Usage:Pharmaceutical intermediates 
  • Brand:GZ 
  • Description:Keywords Gefitinib Gefitinib gefitinib Quick Details ProName: Gefitinib powder CAS NO.184475-35-2 CasNo: 184475-35-2 Molecular Formula: C22H24ClFN4O3 Appearance: powder Application: Used in medical research DeliveryTime: within 3 days after received the paym
  • Updatetime:Dec 13 2018 
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